Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) ELISA Kits

Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. Zusätzlich bieten wir Ihnen Glycoprotein Ib (Platelet), alpha Polypeptide Antikörper (208) und Glycoprotein Ib (Platelet), alpha Polypeptide Proteine (21) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Ratte GP1BA GP1BA 691992  
GP1BA 14723 O35930
GP1BA 2811  
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Top Glycoprotein Ib (Platelet), alpha Polypeptide ELISA Kits auf antikoerper-online.de

Showing 4 out of 14 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.63 ng/mL 1.56-100 ng/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
839,64 €
Details
Maus 11.72 pg/mL 46.88-3000 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
772,39 €
Details
Hund 0.039 ng/mL 0.156-10 ng/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
874,71 €
Details
Human 6.6 pg/mL 15.6-1000 pg/mL   96 Tests Anmelden zum Anzeigen 6 bis 8 Tage
653,71 €
Details

Weitere ELISA Kits für Glycoprotein Ib (Platelet), alpha Polypeptide Interaktionspartner

Cow (Bovine) Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) Interaktionspartner

  1. both the gpIb-VWF (zeige VWF ELISA Kits) interaction and the integrin alpha(2 (zeige ITGA2 ELISA Kits))beta(1)-collagen interaction contribute to platelet adhesion under high shear stress; integrin alpha(II (zeige GSTA3 ELISA Kits))beta(1) makes a greater contribution to adhesion to type I collagen because less VWF (zeige VWF ELISA Kits) is bound

Mouse (Murine) Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) Interaktionspartner

  1. this study shows that atheroma formation is inhibited in GPIba-deficient mice on atherosclerosis-prone background

  2. allosteric inhibitor SbO4L targets the glycoprotein Ibalpha-binding and heparin-binding site of thrombin (zeige F2 ELISA Kits)

  3. Thrombin (zeige F2 ELISA Kits) cleavage of platelet PAR4 (zeige F2RL3 ELISA Kits) promotes leukocyte recruitment to sites of vascular injury. This process is negatively regulated by GPIbalpha.

  4. GPIbalpha-mediated interactions between platelets and endothelial cells, as well as leukocytes, support innate immune cell recruitment and promote arteriogenesis-establishing platelets as critical players in this process.

  5. Atherosclerosis reduction in mice lacking GPIbalpha may not result from the defective GPIbalpha-ligand binding, but more likely is a consequence of functional defects of GPIbalpha-/- platelets and reduced blood platelet counts.

  6. Data suggest that targeting platelet receptor glycoprotein Ibalpha (GPIbalpha)-von Willebrand factor VWF (zeige VWF ELISA Kits)-A1 binding interface may offer a therapeutic approach to reducing platelet-driven thrombosis.

  7. Following endothelial damage, platelet cross-linking during closure of the vessel lumen is mediated by GPIbalpha-VWF (zeige VWF ELISA Kits) interactions.

  8. Platelet IKKbeta (zeige IKBKB ELISA Kits) deficiency increases the formation of injury-induced arterial neointimal tissue via delayed glycoprotein Ibalpha shedding.

  9. these data demonstrate that coordinated expression of GPIbalpha and filamin (zeige FLNA ELISA Kits) is required for efficient trafficking of either protein to the cell surface, and for production of normal-sized platelets.

  10. Desialylation of platelet VWFR therefore triggers platelet clearance and primes GPIbalpha and GPV (zeige GP5 ELISA Kits) for MP-dependent cleavage.

Human Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) Interaktionspartner

  1. Meta-analysis found that glycoprotein Ia (zeige MMRN1 ELISA Kits) C807T T allele or the TT genotype, the Ser (zeige SIGLEC1 ELISA Kits)-allele of HPA-3 and B allele of glycoprotein Ibalpha variable number tandem repeat polymorphisms were associated with increased risk for ischemic stroke.

  2. Our results suggest that the -5CC genotype in Kozak sequence of GPIb-alpha may be associated with a higher risk of developing arterial ischemia of lower limbs in type 2 diabetes mellitus patients.

  3. Specific inhibition of GPIbalpha shedding in the stored platelets improves post-transfusion platelet recovery and hemostatic function, providing clear evidence for GPIbalpha shedding as a cause of platelet clearance.

  4. miR (zeige MLXIP ELISA Kits)-10a and miR10b regulate the expression of human platelet GP1BA and GP1bb (zeige GP1BB ELISA Kits) for normal megakaryopoiesis.

  5. Data indicate that binding of hemoblobin (Hb) to glycoprotein1balpha (GP1balpha) induced platelet activation plays a crucial role in thrombus formation on immobilized von Willebrand factor (VWF (zeige VWF ELISA Kits)) or type I collagen under shear stresses.

  6. allosteric inhibitor SbO4L targets the glycoprotein Ibalpha-binding and heparin-binding site of thrombin (zeige F2 ELISA Kits)

  7. Lateral dimerization of GPIbalpha induced by antibody binding is not sufficient to initiate GPIb-IX signaling and induce platelet clearance.

  8. GPIb alpha plays a critical role in the co-localization of thrombin (zeige F2 ELISA Kits) and factor XI and the resultant efficient activation of FXI (zeige F11 ELISA Kits)

  9. Hemoglobin interaction with GP1balpha induces platelet activation and apoptosis: a novel mechanism associated with intravascular hemolysis.

  10. Both GPIbalpha and PAR4 (zeige PAWR ELISA Kits) are required for thrombin (zeige F2 ELISA Kits)-induced reactive oxygen species formation

Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) Antigen-Profil

Beschreibung des Gens

Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease.

Genbezeichner und Symbole assoziert mit GP1BA

  • glycoprotein Ib (platelet), alpha polypeptide (Gp1ba) Antikörper
  • glycoprotein Ib (platelet), alpha polypeptide (GP1BA) Antikörper
  • glycoprotein 1b, alpha polypeptide (Gp1ba) Antikörper
  • BDPLT1 Antikörper
  • BDPLT3 Antikörper
  • BSS Antikörper
  • CD42B Antikörper
  • CD42b-alpha Antikörper
  • DBPLT3 Antikörper
  • GP1B Antikörper
  • GP1BA Antikörper
  • GPIbA Antikörper
  • GPIbalpha Antikörper
  • VWDP Antikörper

Bezeichner auf Proteinebene für GP1BA

glycoprotein 1b, alpha polypeptide , platelet glycoprotein Ib alpha chain , glycoprotein Ib (platelet), alpha polypeptide , platelet glycoprotein Ib alpha polypeptide , GP-Ib alpha , glycoprotein Ibalpha , antigen CD42b-alpha , platelet membrane glycoprotein 1b-alpha subunit , GPIb-alpha , GPIbA

GENE ID SPEZIES
691992 Rattus norvegicus
420059 Gallus gallus
468166 Pan troglodytes
504977 Bos taurus
14723 Mus musculus
2811 Homo sapiens
403638 Canis lupus familiaris
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