anti-Glutathione S-Transferase alpha 4 (GSTA4) Antikörper

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. Zusätzlich bieten wir Ihnen Glutathione S-Transferase alpha 4 Kits (25) und Glutathione S-Transferase alpha 4 Proteine (20) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
GSTA4 300850 P14942
GSTA4 2941 O15217
GSTA4 14860 P24472
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Top anti-Glutathione S-Transferase alpha 4 Antikörper auf antikoerper-online.de

Showing 10 out of 81 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-GSTA4 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Jurkat cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$326.89
Details
Human Maus Unkonjugiert ELISA, WB Western Blot detection against Immunogen (32.16 KDa) . 50 μL Anmelden zum Anzeigen 11 bis 12 Tage
$298.57
Details
Human Kaninchen Unkonjugiert IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: 293T 12% SDS PAGE GST A4 antibody antibody diluted at 1:1000 IHC-P Image Immunohistochemical analysis of paraffin-embedded SW480 xenograft, using GSTA4, antibody at 1:100 dilution. 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB Western blot analysis of GSTA4 Antibody (N-term) (ABIN652919) in HepG2 cell line lysates (35 µg/lane). GSTA4 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with GSTA4 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Pferd Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Maus Unkonjugiert WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GSTA4 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-GSTA4. 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$423.50
Details
Human Kaninchen Unkonjugiert IHC (p), IHC, WB Western Blot: GSTA4 Antibody [NBP1-32229] - Sample (30 ug of whole cell lysate) A: 293T 12% SDS PAGE GST A4 antibody, antibody diluted at 1:1000. Immunohistochemistry-Paraffin: GSTA4 Antibody [NBP1-32229] - Paraffin-embedded SW480 xenograft, using antibody at 1:100 dilution. 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$447.56
Details

GSTA4 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Rat (Rattus)


Human , , ,
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Mouse (Murine)


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Am meisten referenzierte anti-Glutathione S-Transferase alpha 4 Antikörper

  1. Human Polyclonal GSTA4 Primary Antibody für ELISA, WB - ABIN561161 : Grimsrud, Picklo, Griffin, Bernlohr: Carbonylation of adipose proteins in obesity and insulin resistance: identification of adipocyte fatty acid-binding protein as a cellular target of 4-hydroxynonenal. in Molecular & cellular proteomics : MCP 2007 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal GSTA4 Primary Antibody für WB - ABIN516227 : Yang, Huycke, Herman, Wang: Glutathione S-transferase alpha 4 induction by activator protein 1 in colorectal cancer. in Oncogene 2016 (PubMed)

Weitere Antikörper gegen Glutathione S-Transferase alpha 4 Interaktionspartner

Human Glutathione S-Transferase alpha 4 (GSTA4) Interaktionspartner

  1. These findings demonstrate GSTA4 activation during 4-HNE (zeige ELANE Antikörper)-induced neoplastic transformation in colorectal carcinogenesis. GSTA4 is a potential surrogate biomarker for CRC (zeige CALR Antikörper) screening and should provide novel approaches for chemoprevention.

  2. Decreased gene expression of GSTA4 is associated with drug resistance in cervical cancer.

  3. Data indicate that steroidogenic factor 1 (SF-1 (zeige NR5A1 Antikörper)) and glutathione S-transferase A (GSTA (zeige GSTa2 Antikörper)) family genes (hGSTA1-hGSTA4) are involved in steroidogenesis.

  4. GSTA4 down-regulation and the concomitant increase in 4-hydroxynonenal adducts in muscle are indicative of susceptibility to infection in individuals with severe thermal injuries.

  5. Data show that mandatory overexpression of hGSTA4 by transient transfection in KYSE30 cells and attenuation of HNE (zeige ELANE Antikörper)-induced EGFR (zeige EGFR Antikörper) phosphorylation.

  6. analysis of four novel mutations that change the function of leukotriene C(4) synthase (zeige LTC4S Antikörper) and are associated with increased risk of venous thromboembolism and ischemic stroke

  7. Gsta4/GSTA4 is a novel susceptibility gene for NMSC that affects risk in both mice and humans.

  8. Results indicate that downregulation of GSTA4 in adipose tissue leads to increased protein carbonylation, ROS (zeige ROS1 Antikörper) production, and mitochondrial dysfunction and may contribute to the development of insulin (zeige INS Antikörper) resistance and type 2 diabetes.

  9. GSTA4-4 exploits the hydroxyl group of either 4R- or 4S-hydroxynonenal (HNE (zeige ELANE Antikörper)), while specifically binding HNE (zeige ELANE Antikörper) and glutathione (GSH) to maintain high catalytic efficiency linked with stereoselective product formation for both enantiomeric substrates.

  10. null mice had a significantly lower survival time than wild-type controls when chronically treated with relatively low doses of paraquat, a finding consistent with a role of glutathione transferase A4-4 in the defense against oxidative stress

Mouse (Murine) Glutathione S-Transferase alpha 4 (GSTA4) Interaktionspartner

  1. Data define a role for GSTA4-4 in buffering hepatic oxidative stress associated with chronic alcohol consumption and that this GST isoform plays an important role in protecting against carbonylation of mitochondrial proteins.

  2. although loss of GSTA4-4 led to enhanced susceptibility of cardiac mitochondria to radiation-induced loss of morphology, cardiac function was preserved in Gsta4-null mice

  3. These results indicate that 4-HNE (zeige ELANE Antikörper) significantly contributes to the mechanisms of tubule injury and fibrosis and that these effects can be inhibited by the enhanced expression of GSTA4-4.

  4. In the absence of GSTA4-4 to modulate both physiological and pathological 4-hydroxynonenal (HNE (zeige ELANE Antikörper)) levels, the adaptive NRF (zeige NKRF Antikörper)-E2-related (Nrf)2 (zeige NFE2L2 Antikörper) factor pathway may be primed to contribute to a preconditioned cardiac phenotype in the Gsta4-null mouse.

  5. The naturally occurring variation in Gsta4 expression in rats affects neurodegeneration after TBI. Further studies are needed to explore if genetic variability in Gsta4 can be associated to outcome also in human TBI.

  6. 2-APB (zeige RNPEP Antikörper) treatment restrained nasal lavage fluid LTC4, ECP (zeige ECP Antikörper), ovalbumin (zeige OVA Antikörper)-specific IgE, and IL-4 (zeige IL4 Antikörper) and their corresponding mRNAs in the previously mentioned tissues of treated mice in comparison with those of control ones.

  7. Gsta4/GSTA4 is a novel susceptibility gene for NMSC that affects risk in both mice and humans.

  8. Results indicate that downregulation of GSTA4 in adipose tissue leads to increased protein carbonylation, ROS (zeige ROS1 Antikörper) production, and mitochondrial dysfunction and may contribute to the development of insulin (zeige INS Antikörper) resistance and type 2 diabetes.

  9. mGsta4-null mice, in which 4-HNE (zeige ELANE Antikörper) detoxification is impaired, have an extended life span.

  10. in regenerating hepatocytes, several GST isoforms are induced and that cytokines TNFalpha (zeige TNF Antikörper) and IL-6 (zeige IL6 Antikörper) and survival factor EGF (zeige EGF Antikörper) positively regulate mGSTA4 via survival signaling pathways.

Glutathione S-Transferase alpha 4 (GSTA4) Antigen-Profil

Protein Überblick

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, which are located in a cluster on chromosome 6, are highly related and encode enzymes with glutathione peroxidase activity that function in the detoxification of lipid peroxidation products. Reactive electrophiles produced by oxidative metabolism have been linked to a number of degenerative diseases including Parkinson's disease, Alzheimer's disease, cataract formation, and atherosclerosis.

Genbezeichner und Symbole assoziert mit GSTA4

  • glutathione S-transferase alpha 4 (GSTA4) Antikörper
  • glutathione S-transferase alpha 4 (gsta4) Antikörper
  • glutathione S-transferase alpha 4 (Gsta4) Antikörper
  • glutathione S-transferase alpha 4 (LOC100341622) Antikörper
  • glutathione S-transferase mu 2 (Gstm2) Antikörper
  • glutathione S-transferase, alpha 3 (GSTA3) Antikörper
  • glutathione S-transferase, alpha 4 (Gsta4) Antikörper
  • GST5.7 Antikörper
  • GSTA4 Antikörper
  • GSTA4-4 Antikörper
  • GTA4 Antikörper
  • mGsta4 Antikörper
  • tGSTA4 Antikörper

Bezeichner auf Proteinebene für GSTA4

glutathione S-transferase A4 , glutathione S-transferase alpha class A4 , GST 8-8 , GST A4-4 , GST K , GST Yk , glutathione S-transferase Yk , glutathione S-transferase alpha-4 , glutathione transferase , GST class-alpha member 4 , S-(hydroxyalkyl)glutathione lyase A4 , glutathione S-alkyltransferase A4 , glutathione S-aralkyltransferase A4 , glutathione S-aryltransferase A4 , glutathione S-transferase A4-4 , glutathione transferase A4-4 , GST 4-4 , GST Yb2 , GSTM2-2 , Glutathione-S-transferase mu type 2 (Yb2) , Glutathione-S-transferase, mu type 2 (Yb2) , glutathione S-transferase M2 , glutathione S-transferase Mu 2 , glutathione S-transferase Yb-2 , glutathione S-transferase Yb2 subunit , GSTA4-4 , glutathione S-transferase 5.7

GENE ID SPEZIES
462771 Pan troglodytes
549430 Xenopus (Silurana) tropicalis
734548 Xenopus laevis
100379163 Meleagris gallopavo
300850 Rattus norvegicus
2941 Homo sapiens
474939 Canis lupus familiaris
533917 Bos taurus
100152951 Sus scrofa
100341622 Oryctolagus cuniculus
24424 Rattus norvegicus
768055 Bos taurus
14860 Mus musculus
Ausgewählte Anbieter für anti-Glutathione S-Transferase alpha 4 (GSTA4) Antikörper
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