anti-Glutamate Receptor, Metabotropic 4 (GRM4) Antikörper

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Zusätzlich bieten wir Ihnen Metabotropic Glutamate Receptor 4 Kits (15) und Metabotropic Glutamate Receptor 4 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
GRM4 2914 Q14833
GRM4 268934 Q68EF4
GRM4 24417 P31423
Direkt bei antikoerper-online bestellen
  • +49 (0)241 95 163 153
  • +49 (0)241 95 163 155
  • Online bestellen
  • orders@antikoerper-online.de

Top anti-Metabotropic Glutamate Receptor 4 Antikörper auf antikoerper-online.de

Showing 10 out of 44 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Huhn Kaninchen Unkonjugiert IC, IF, IHC, WB Immunofluorescent analysis of mGLUR4 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of mGLUR4 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Anmelden zum Anzeigen 11 bis 13 Tage
464,29 €
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of rat (lanes 1 and 3) and mouse (lanes 2 and 4) brain membranes: 1, 2. Anti-mGluR4 (extracellular) antibody, (1:200). 3, 4. Anti-mGluR4 (extracellular) antibody, preincubated with the control peptide antigen. 50 μL Anmelden zum Anzeigen 14 bis 16 Tage
672,45 €
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB Western Blot (WB) analysis of specific cells using mGluR-4 Polyclonal Antibody. 100 μL Anmelden zum Anzeigen 13 Days
154,33 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti-MGLUR4 antibody IHC staining of human brain, cortex, neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1048935 dilution 19 ug/ml. Anti-MGLUR4 antibody IHC staining of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1048935 dilution 19 ug/ml. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
501,70 €
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC (p) Anti-GRM4 / MGLUR4 antibody  ABIN1048936 IHC staining of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
501,70 €
Details
Human Schaf Unkonjugiert CyTOF, FACS, IHC Detection of mGluR4 in HT1080 Human Cell Line by Flow Cytometry. mGluR4 in Human Endothelial Cells. mGluR4 was detected in immersion fixed paraffin-embedded sections of human brainstem (medulla) using Sheep Anti-Human mGluR4 Antigen Affinity-purified Polyclonal Antibody. Specific staining was localized to endothelial cells in vasculature. 100 μg Anmelden zum Anzeigen 3 bis 4 Tage
355,00 €
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot analysis of extracts from 293 cells, treated with Forskolin 40nM 30', using mGluR4 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using mGluR4 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB Immunohistochemistry-Paraffin: mGluR4 Antibody [NLS4713] - Analysis of anti-MGLUR4 antibody with human brain, cortex, neurons at dilution 19 ug/ml. Immunohistochemistry-Paraffin: mGluR4 Antibody  - Anti-MGLUR4 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 19 ug/ml. 0.05 mL Anmelden zum Anzeigen 5 bis 8 Tage
341,00 €
Details
Human Kaninchen Unkonjugiert IHC (p), ELISA, WB Anti-GRM4 / MGLUR4 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1101897 concentration 10 ug/ml. 50 μL Anmelden zum Anzeigen 11 bis 14 Tage
501,70 €
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC (p) Immunohistochemistry-Paraffin: mGluR4 Antibody  - Analysis of anti-GRM4 / MGLUR4 antibody with human brain, glioblastoma. Immunohistochemistry-Paraffin: mGluR4 Antibody  - Analysis of anti-GRM4 / MGLUR4 antibody with human brain, neurons and glia. 0.05 mL Anmelden zum Anzeigen 2 bis 4 Tage
341,00 €
Details

GRM4 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Human , , ,
,

Mouse (Murine) , ,


Rat (Rattus) , ,


Weitere Antikörper gegen Metabotropic Glutamate Receptor 4 Interaktionspartner

Human Glutamate Receptor, Metabotropic 4 (GRM4) Interaktionspartner

  1. Results suggest that variant rs2229901 of glutamate receptor 4 (zeige GRIA4 Antikörper) is associated with major depressive disorder risk. This variant probably impacts the interaction between GRM4 and miR (zeige MLXIP Antikörper)-1202.

  2. Our data suggest that GRM4 gene polymorphism is closely related to the morbidity and metastasis of osteosarcoma in a Chinese population.

  3. The GRM4 gene polymorphism was associated with the susceptibility and metastasis of osteosarcoma in a Chinese Han population.

  4. The major depression subjects exhibited significantly higher expression level in the metabotropic receptor genes GRM4 in Locus coeruleus neurons.

  5. explored the relationship between the binding pockets of mGlu4-positive allosteric modulators with different chemical scaffolds and their functional properties

  6. Data show that mGlu2 (zeige GRM2 Antikörper) and mGlu4 subunits (but not mGlu2 (zeige GRM2 Antikörper) and mGlu1 (zeige GRM1 Antikörper)) can heteromerize.

  7. GRM4 sequence variants might confer low-risk effects to the etiology of idiopathic generalized epilepsies.

  8. residues shaping the binding pocket determine ligand selectivity for mGLUR4

  9. mGluR4 has a role in 5-FU resistance in colonic neoplasms

  10. Results suggest that overexpression of mGluR4 is associated with poor prognosis.

Mouse (Murine) Glutamate Receptor, Metabotropic 4 (GRM4) Interaktionspartner

  1. This immuno-electron microscopic studies suggest that pre-synaptic metabotropic glutamate receptor 4 (mGluR4) in striatal glutamatergic terminals is expressed almost exclusively in cortical boutons to subserve regulatory influences upon a large contingent of corticostriatal terminals that preferentially target putative "indirect" pathway striatal projection neurons in mice.

  2. Study assessed the actions of the first mGlur4-selective orthosteric agonist, LSP4-2022, in several tests reflecting positive, negative, and cognitive symptoms of schizophrenia; results suggest that the interplay between mGlu4 and GABAB receptors may become the basis for a novel therapy for schizophrenic patients with predomination of positive symptoms

  3. Results offer the first evidence that changes in the striatal expression of mGlu4 and mGlu5 (zeige GRM5 Antikörper) receptors occur in acute models of parkinsonisms

  4. Involvement of multiple taste receptors in umami taste: analysis of gustatory nerve responses in metabotropic glutamate receptor 4 knockout mice

  5. A functional hetero-complex is formed with mGluR2 (zeige GRM2 Antikörper) and mGluR4 in central nervous system.

  6. mGluR4-/- mice show increased long-term potentiation in hippocampal CA1 (zeige CA1 Antikörper) region and improved maze learning.

  7. data support a role for mGluR4 signaling in acquisition of fear learning and memory.

  8. The expression of mGluR4 is down-regulated in the cardiomyocyte differentiation of embryonic stem cells.

  9. These data indicate that effects of mGluR4 on sensorimotor function and measures of anxiety, but not cued fear conditioning, are critically modulated by sex and age.

  10. A role for mGlu4 was found whereby simultaneous activation with GABA(A) receptors acts to amplify glutamate (zeige GRIN1 Antikörper) release at parallel fiber-Purkinje cell synapses.

Metabotropic Glutamate Receptor 4 (GRM4) Antigen-Profil

Protein Überblick

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Several transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit GRM4

  • metabotropic glutamate receptor 4 (MGLUR4) Antikörper
  • glutamate receptor, metabotropic 4 (GRM4) Antikörper
  • glutamate receptor, metabotropic 4 (Grm4) Antikörper
  • Gprc1d Antikörper
  • mGlu4 Antikörper
  • mGluR4 Antikörper

Bezeichner auf Proteinebene für GRM4

metabotropic glutamate receptor 4 , G protein-coupled receptor GRM4 , G protein-coupled receptor, family C, group 1, member D , mGluR4

GENE ID SPEZIES
443291 Ovis aries
2914 Homo sapiens
268934 Mus musculus
24417 Rattus norvegicus
100152616 Sus scrofa
101119427 Ovis aries
Ausgewählte Anbieter für anti-Metabotropic Glutamate Receptor 4 (GRM4) Antikörper
Haben Sie etwas anderes gesucht?