anti-Glutamate Receptor, Metabotropic 1 (GRM1) Antikörper

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Zusätzlich bieten wir Ihnen Metabotropic Glutamate Receptor 1 Kits (14) und Metabotropic Glutamate Receptor 1 Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
GRM1 2911 Q13255
GRM1 14816 P97772
GRM1 24414 P23385
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Top anti-Metabotropic Glutamate Receptor 1 Antikörper auf antikoerper-online.de

Showing 10 out of 142 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB GRM1 Antibody (C-term) (ABIN657624) western blot analysis in CEM cell line lysates (35 µg/lane). This demonstrates the GRM1 antibody detected the GRM1 protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Maus Maus Unkonjugiert IF, WB Western blot analysis of mGluR1 on a rat cerebrum lysate. Lane 1: 1:2500, lane 2: 1:5000, lane 3: 1: 10,000 dilution of the mouse anti-mGluR1 antibody. Immunofluorescence staining of cortical neurons. 50 μg Anmelden zum Anzeigen 2 bis 4 Tage
146,73 €
Details
Human Kaninchen Unkonjugiert IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using GRM1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB GPRC1A Antibody (Y1111) (ABIN652203) western blot analysis in NCI-H460 cell line lysates (35 µg/lane).This demonstrates the GPRC1A antibody detected the GPRC1A protein (arrow). Metabotropic Glutamate Receptor 1 (GPRC1A) Antibody (C-term) (ABIN652203)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Ratte Kaninchen Unkonjugiert IHC (fro), WB 10 blots Anmelden zum Anzeigen 7 bis 9 Tage
517,00 €
Details
Human Kaninchen Unkonjugiert FACS, IP, IHC, WB Western blot analysis of rat brain lysate: 1. Anti-mGluR1 (extracellular) antibody, (1:200). 2. Anti-mGluR1 (extracellular) antibody, preincubated with the control peptide antigen. Western blot analysis of mouse brain lysate: 1. Anti-mGluR1 (extracellular) antibody, (1:200). 2. Anti-mGluR1 (extracellular) antibody, preincubated with the control peptide antigen. 50 μL Anmelden zum Anzeigen 14 bis 16 Tage
672,45 €
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC (p) Anti-GRM1 / MGLUR1 antibody  ABIN1048925 IHC staining of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
501,70 €
Details
Human Kaninchen Unkonjugiert IHC (fro), FACS, IHC (p), IP 250 μL Anmelden zum Anzeigen 8 bis 10 Tage
456,00 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with GRM1 antibody ABIN239868 at 20 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
501,70 €
Details
Human Maus Unkonjugiert FACS Surface staining of lysed and washed porcine peripheral blood with purified anti-CD16 (MEM-168) (detection by anti-mouse IgM FITC). Panel A - porcine PBMC stained with Isotype mouse IgM control (PFR-03) Panel B, C, D - three different porcine PMBC samples stained with anti-CD16 Cells in the granulocyte gate were used for analysis. 0.1 mg Anmelden zum Anzeigen 2 bis 4 Tage
198,00 €
Details

GRM1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Metabotropic Glutamate Receptor 1 Antikörper

  1. Human Monoclonal Metabotropic Glutamate Receptor 1 Primary Antibody für FACS, Func - ABIN807922 : Zhu, Hamann, Muñoz, Rubio, Mayer, Hernrreiter, Leff: Intracellular expression of Fc gamma RIII (CD16) and its mobilization by chemoattractants in human eosinophils. in Journal of immunology (Baltimore, Md. : 1950) 1998 (PubMed)
    Show all 7 Pubmed References

  2. Human Monoclonal Metabotropic Glutamate Receptor 1 Primary Antibody für FACS, Func - ABIN780366 : Choi, Wang, Peterson, Letvin, Reimann: Use of an anti-CD16 antibody for in vivo depletion of natural killer cells in rhesus macaques. in Immunology 2008 (PubMed)
    Show all 6 Pubmed References

  3. Human Monoclonal Metabotropic Glutamate Receptor 1 Primary Antibody für FACS, Func - ABIN1027684 : Metes, Ernst, Chambers, Sulica, Herberman, Morel: Expression of functional CD32 molecules on human NK cells is determined by an allelic polymorphism of the FcgammaRIIC gene. in Blood 1998 (PubMed)
    Show all 7 Pubmed References

  4. Mouse (Murine) Monoclonal Metabotropic Glutamate Receptor 1 Primary Antibody für IF, WB - ABIN968280 : Gomeza, Joly, Kuhn, Knöpfel, Bockaert, Pin: The second intracellular loop of metabotropic glutamate receptor 1 cooperates with the other intracellular domains to control coupling to G-proteins. in The Journal of biological chemistry 1996 (PubMed)
    Show all 5 Pubmed References

  5. Mouse (Murine) Monoclonal Metabotropic Glutamate Receptor 1 Primary Antibody für IF, WB - ABIN968281 : Kryl, Yacoubian, Haapasalo, Castren, Lo, Barker: Subcellular localization of full-length and truncated Trk receptor isoforms in polarized neurons and epithelial cells. in The Journal of neuroscience : the official journal of the Society for Neuroscience 1999 (PubMed)
    Show all 5 Pubmed References

  6. Human Monoclonal Metabotropic Glutamate Receptor 1 Primary Antibody für FACS, IP - ABIN93988 : Kahn, Moergelin, Shannon, Norrby-Teglund, Herwald, Olin, Bjoerck: Antibodies against a surface protein of Streptococcus pyogenes promote a pathological inflammatory response. in PLoS pathogens 2008 (PubMed)
    Show all 14 Pubmed References

  7. Human Monoclonal Metabotropic Glutamate Receptor 1 Primary Antibody für FACS, IP - ABIN93989 : Mathison, Christie, Davison: The tripeptide feG inhibits leukocyte adhesion. in Journal of inflammation (London, England) 2008 (PubMed)
    Show all 14 Pubmed References

  8. Human Monoclonal Metabotropic Glutamate Receptor 1 Primary Antibody für FACS, IP - ABIN93990 : Meknache, Joensson, Laurent, Guinnepain, Daueron: Human basophils express the glycosylphosphatidylinositol-anchored low-affinity IgG receptor FcgammaRIIIB (CD16B). in Journal of immunology (Baltimore, Md. : 1950) 2009 (PubMed)
    Show all 14 Pubmed References

  9. Human Monoclonal Metabotropic Glutamate Receptor 1 Primary Antibody für FACS - ABIN93997 : Drbal, Moertelmaier, Holzhauser, Muhammad, Fuertbauer, Howorka, Hinterberger, Stockinger, Schütz: Single-molecule microscopy reveals heterogeneous dynamics of lipid raft components upon TCR engagement. in International immunology 2007 (PubMed)
    Show all 4 Pubmed References

Weitere Antikörper gegen Metabotropic Glutamate Receptor 1 Interaktionspartner

Human Glutamate Receptor, Metabotropic 1 (GRM1) Interaktionspartner

  1. Missense Mutation in GRM1 gene is associated with Spinocerebellar Ataxia Type 44.

  2. our findings suggest that pharmacological manipulation of mglur1 should be explored as an exciting new approach for the treatment of a variety of human cerebellar ataxias.

  3. a missense variant was found in GRM1 gene, while in the second family, a frameshift alteration was identified in TRMT1 (zeige TRMT1 Antikörper), both of which were found to co-segregate with the intellectual disability.

  4. It has the intrinsic ability to form a heteromeric complex with adenosine A1 receptor (zeige ADORA1 Antikörper) and mutually modulate signaling.

  5. These data demonstrate that the approaches commonly used to study mGlu1 receptor function and signaling in other systems may be inappropriate for studying mGlu1 receptor-mediated melanoma cell viability.

  6. Our results are likely relevant to human breast cancer, highlighting a putative role of mGluR1 in the pathophysiology of breast cancer and the potential of mGluR1 as a novel therapeutic target.

  7. elevated glutamate (zeige GRIN1 Antikörper) secretion and mGluR1 expression play a role in Kaposi's sarcoma associated herpesvirus induced cell proliferation

  8. alpha-actinin-4 (zeige ACTN4 Antikörper) is a novel group 1 mGluR (zeige GRM8 Antikörper)-interacting partner that orchestrates spine dynamics and morphogenesis in neurons.

  9. Deleterious GRM1 mutations are associated with schizophrenia.

  10. These novel mutations may contribute to the disease by alterations in GRM1 gene splicing, receptor activation, and post-receptor downstream signaling.

Mouse (Murine) Glutamate Receptor, Metabotropic 1 (GRM1) Interaktionspartner

  1. The results of our study showed that thalamic mGluR1-PLCbeta4 pathway was critical in controlling sleep architecture.

  2. This study confirmed the presence of mGluR1/5 complex by (i) reverse immunoprecipitation using an mGluR1 antibody to pulldown mGluR5 (zeige GRM5 Antikörper) from hippocampal tissue.

  3. results demonstrate that mGluR1 is crucial for the visual-experience-dependent maintenance of mature synaptic connectivity in the dorsal Lateral Geniculate Nuc.

  4. These results suggest that impairment of synaptic mGluR (zeige GRM8 Antikörper) cascades is one of the important contributing factors to cerebellar ataxia in early and middle stages of spinocerebellar ataxia type 1 (SCA1 (zeige ATXN1 Antikörper)) pathology, and that modulation of mGluR (zeige GRM8 Antikörper) signalling by baclofen or other clinical interventions may be therapeutic targets to treat SCA1 (zeige ATXN1 Antikörper)

  5. activation of mGluR1 expressed by OCCM (zeige LAMC3 Antikörper)-30 cells induces cell proliferation in a manner that is dependent on mitogen-activated protein kinase (zeige MAPK1 Antikörper) pathways.

  6. In a mouse model of human spino (zeige PPP1R9B Antikörper)-cerebellar ataxia type 1 (early SCA1 (zeige ATXN1 Antikörper), 12 weeks) we find prolonged parallel fiber mGluR1-dependent synaptic currents and calcium signaling

  7. Here we identify mGluR1 and mGluR5 (zeige GRM5 Antikörper) as key elements in the dynamic regulation of cholinergic synaptic inputs onto neurons of the TRN (zeige TNPO1 Antikörper). Our findings highlight potential mechanisms that regulate cholinergic signaling in the mammalian brain.

  8. data suggest that Lys (zeige LYZ Antikörper)(63)-linked polyubiquitination is involved in the ligand-mediated endocytosis of mGluR1.

  9. This study provides evidence that ASIC1a (zeige ACCN2 Antikörper) is involved in group I metabotropic glutamate (zeige GRIN1 Antikörper) (mGlu) receptor-induced increase in action potential firing.

  10. Homodimerization enhances both sensitivity and dynamic range of the ligand-binding domain of type 1 metabotropic glutamate (zeige GRIN1 Antikörper) receptor

Metabotropic Glutamate Receptor 1 (GRM1) Antigen-Profil

Protein Überblick

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. The canonical alpha isoform of the metabotropic glutamate receptor 1 gene is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. Alternative splicing results in multiple transcript variants encoding distinct isoforms\; some of which may have distinct functions.

Genbezeichner und Symbole assoziert mit GRM1

  • glutamate receptor, metabotropic 1 (GRM1) Antikörper
  • glutamate receptor, metabotropic 1a (grm1a) Antikörper
  • metabotropic glutamate receptor 1 (mGlutR1) Antikörper
  • glutamate receptor, metabotropic 1 (Grm1) Antikörper
  • 4930455H15Rik Antikörper
  • ENSMUSG00000075319 Antikörper
  • fj39d05 Antikörper
  • GB18621 Antikörper
  • Glura Antikörper
  • Gm10828 Antikörper
  • Gprc1a Antikörper
  • MGLU1 Antikörper
  • mGluR1 Antikörper
  • mGlutR Antikörper
  • nmf373 Antikörper
  • rcw Antikörper
  • SCAR13 Antikörper
  • si:ch211-51a19.1 Antikörper
  • wobl Antikörper
  • wu:fj39d05 Antikörper

Bezeichner auf Proteinebene für GRM1

metabotropic glutamate receptor 1 , metabotropic glutamate receptor A , G protein coupled receptor, family C, group 1, member A , G protein-coupled receptor, family C, group 1, member A , G protein coupled receptor family C group 1 member A , mGluR1

GENE ID SPEZIES
100060603 Equus caballus
463049 Pan troglodytes
555576 Danio rerio
406151 Apis mellifera
2911 Homo sapiens
100625610 Sus scrofa
14816 Mus musculus
24414 Rattus norvegicus
421614 Gallus gallus
484024 Canis lupus familiaris
540485 Bos taurus
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