anti-Glucosaminyl (N-Acetyl) Transferase 1, Core 2 (GCNT1) Antikörper

GCNT1 is a member of the beta-1,6-N-acetylglucosaminyltransferase gene family. Zusätzlich bieten wir Ihnen GCNT1 Kits (13) und GCNT1 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
GCNT1 2650 Q02742
GCNT1 14537 Q09324
GCNT1 64043  
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Top anti-GCNT1 Antikörper auf antikoerper-online.de

Showing 10 out of 68 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC (p), WB The anti-GCNT1 Pab (ABIN389033) is used in Western blot to detect GCNT1 in mouse kidney tissue lysate. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
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Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of anti-GCNT1 Antibody (C-term) (ABIN389034) in CEM cell line lysates (35 µg/lane). GCNT1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert WB GCNT1 Antibody (Center)  western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the GCNT1 antibody detected the GCNT1 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Maus Unkonjugiert WB Western Blot analysis of GCNT1 expression in transfected 293T cell line by GCNT1 MaxPab polyclonal antibody.<br><br>Lane1:GCNT1 transfected lysate(47.08 KDa).<br>Lane2:Non-transfected lysate.<br> 50 μg Anmelden zum Anzeigen 11 bis 12 Tage
$430.00
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Immunohistochemistry: Glucosaminyl (N-acetyl) Transferase 1/GCNT1 Antibody [NBP1-86809] - Staining of human small intestine shows cytoplasmic and membranous positivity in glandular cells. Immunohistochemistry-Paraffin: Glucosaminyl (N-acetyl) Transferase 1/GCNT1 Antibody [NBP1-86809] - Staining of human duodenum shows strong cytoplasmic positivity in glandular cells. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$439.69
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$295.90
Details
Human Kaninchen Unkonjugiert IHC (p), WB Antibody is used in Western blot to detect GCNT1 in mouse kidney tissue lysate. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. BC = breast carcinoma; HC = hepatocarcinoma. 400 μL Anmelden zum Anzeigen 2 bis 3 Tage
$515.63
Details
Human Kaninchen Unkonjugiert WB Western blot analysis in T47D cell line lysates (35ug/lane). 400 μL Anmelden zum Anzeigen 2 bis 3 Tage
$515.63
Details

GCNT1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-GCNT1 Antikörper

  1. Human Polyclonal GCNT1 Primary Antibody für WB - ABIN515997 : Petrosyan, Cheng: Golgi fragmentation induced by heat shock or inhibition of heat shock proteins is mediated by non-muscle myosin IIA via its interaction with glycosyltransferases. in Cell stress & chaperones 2014 (PubMed)

Weitere Antikörper gegen GCNT1 Interaktionspartner

Human Glucosaminyl (N-Acetyl) Transferase 1, Core 2 (GCNT1) Interaktionspartner

  1. GCNT1 expression in prostate biopsy specimen is a significant and independent predictor of recurrence after radical prostatectomy, which can be used in pre-treatment decision making for the patient.

  2. GCNT1 expression in prostate cancer positively correlates with cancer progression and prostate-specific antigen recurrence.

  3. Results show that ST3Gal1 (zeige ST3GAL1 Antikörper) uses GM130 (zeige GOLGA2 Antikörper)-GRASP65 (zeige GORASP1 Antikörper) and giantin (zeige GOLGB1 Antikörper), whereas C2GnT-L uses only giantin (zeige GOLGB1 Antikörper) for Golgi targeting and defective giantin (zeige GOLGB1 Antikörper) dimerization in PC-3 (zeige PCSK1 Antikörper) and DU145 prostate cancer cells causes fragmentation of the Golgi and prevents its targeting.

  4. NMIIA is the master regulator of Golgi fragmentation induced by heat shock or inhibition/depletion of HSP70 (zeige HSP70 Antikörper)/90 through interaction with gylosyltransferases.

  5. GCNT1 is over-expressed in prostate cancer and is associated with higher levels of core 2 O-sLe(x) in PSA (zeige PLAG1 Antikörper), PAP (zeige REG3A Antikörper) and MUC1 (zeige MUC1 Antikörper) proteins.

  6. Immunohistochemical expression of core 2 beta1,6-N-acetylglucosaminyl transferase 1 (C2GnT1) in endometrioid-type endometrial carcinoma may be a novel potential prognostic factor.

  7. C2GnT-expressing prostate cancer cells evade NK cell immunity and survive longer in the host blood circulation, thereby resulting in the promotion of prostate cancer metastasis.

  8. GOLPH3 (zeige GOLPH3 Antikörper) can regulate cell-cell interaction by controlling Golgi retention of C2GnT1.

  9. Down-regulation of C2GnT1 is correlated with breast cancer

  10. The X-ray crystal structure (2.3 A resolution) of a mutant form of C2GnT-L (C217S) in complex with UDP was solved. C2GnT-L exists in an "open" conformation and a "closed" conformation.

Mouse (Murine) Glucosaminyl (N-Acetyl) Transferase 1, Core 2 (GCNT1) Interaktionspartner

  1. we show that Gcnt1 transcription and subsequent P-lselectin ligand induction in Th1 cells is governed by binding of STAT4 and T-bet to a distal enhancer and further regulated by epigenetic marks such as H3K27me3.

  2. simultaneous deletion of the Core2 beta1,6-N-acetylglucosaminyltransferase (C2GnT) enzymes C2GnT1 and C2Gnt2 (zeige GCNT3 Antikörper) resulted in delayed expulsion of worms.

  3. striking differences between the requirement of FucT-VII (zeige FUT7 Antikörper) and C2GlcNAcT-I for Ligands for E-selectin (zeige SELE Antikörper) and P-selectin (zeige SELP Antikörper) expression in CD4 (zeige CD4 Antikörper)+ T cells.

  4. Core2 O-glycan structure is essential for expression of SI and DDP (zeige TIMM8A Antikörper)-IV during intestinal cell differentiation.

  5. Distinct functions for C2GlcNAcT-I in the differential elaboration of endothelial venule glycoproteins that set a threshold for the amount of L-selectin (zeige SELL Antikörper) needed for lymphocyte homing.

  6. data demonstrate that multiple C2GlcNAcT enzymes can contribute to P-selectin (zeige SELP Antikörper) ligand formation and may cooperate with C2GlcNAcT-I in the control of CD8 (zeige CD8A Antikörper) T cell trafficking

  7. IGnT deficient mice had reduced spontaneous locomotive activity, and the number of peripheral blood lymphocytes was also reduced and renal function decreased in the deficient mice

  8. Data report the x-ray crystal structures of murine core 2 O-glycan (Galbeta1-3[GlcNAcbeta1-6]GalNAc-O-Ser (zeige SIGLEC1 Antikörper)/Thr (zeige TRH Antikörper)) (C2GnT-L) in the absence and presence of the acceptor substrate Galbeta1-3GalNAc at 2.0 and 2.7A resolution, respectively.

  9. These results suggest that the core 2 GlcNAc extended glycan chains on megalin (zeige LRP2 Antikörper) can change the ligand-binding affinity and capacity.

  10. Pancreas carcinoma antigen, C2GnT, fused to invariant chain elicits T-cell response and tumor growth inhibition.

GCNT1 Antigen-Profil

Protein Überblick

This gene is a member of the beta-1,6-N-acetylglucosaminyltransferase gene family. It is essential to the formation of Gal beta 1-3(GlcNAc beta 1-6)GalNAc structures and the core 2 O-glycan branch. The gene coding this enzyme was originally mapped to 9q21, but was later localized to 9q13. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Genbezeichner und Symbole assoziert mit GCNT1

  • glucosaminyl (N-acetyl) transferase 1, core 2 L homeolog (gcnt1.L) Antikörper
  • glucosaminyl (N-acetyl) transferase 1, core 2 (GCNT1) Antikörper
  • glucosaminyl (N-acetyl) transferase 1, core 2 (Gcnt1) Antikörper
  • 5630400D21Rik Antikörper
  • B130048E03 Antikörper
  • C2 GlcNAcT Antikörper
  • C2GNT Antikörper
  • C2GNT-L Antikörper
  • C2GNT1 Antikörper
  • core 2 GlcNAc-T Antikörper
  • G6NT Antikörper
  • IGnT Antikörper
  • NACGT2 Antikörper
  • NAGCT2 Antikörper

Bezeichner auf Proteinebene für GCNT1

enzymatic glycosylation-regulating , glucosaminyl (N-acetyl) transferase 1, core 2 (beta-1,6-N-acetylglucosaminyltransferase) , Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase , glucosaminyl (N-acetyl) transferase 1, core 2 , glucosaminyl transferase 1, core 2 , beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase-like , beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N--acetylglucosaminyltransferase , beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase , beta-1,6-N-acetylglucosaminyltransferase , core 2 GnT , core 2 beta-1,6-N-acetylglucosaminyltransferase I , core 2 beta1,6 N-acetylglucosaminyltransferase-I , core 2 branching enzyme , core 2-branching enzyme , core2-GlcNAc-transferase , beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase (Core 2 branching enzyme) (Core2-GlcNAc-transferase) (C2GNT) , C2GNT , core 2 GNT , beta1,6 N-acetylglucosaminyltransferase

GENE ID SPEZIES
380501 Xenopus laevis
427260 Gallus gallus
704639 Macaca mulatta
100011966 Monodelphis domestica
100347030 Oryctolagus cuniculus
100397450 Callithrix jacchus
100453351 Pongo abelii
100481771 Ailuropoda melanoleuca
100590764 Nomascus leucogenys
2650 Homo sapiens
14537 Mus musculus
281778 Bos taurus
484158 Canis lupus familiaris
64043 Rattus norvegicus
101121316 Ovis aries
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