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GCM1 encodes a DNA-binding protein with a gcm-motif (glial cell missing motif). Zusätzlich bieten wir Ihnen GCM1 Antikörper (46) und GCM1 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.
chromosomal localization of the porcine GCM1 gene and the identification and characterization of a GCM1 associated microsatellite marker [GCM1]
results suggest that p45 NF-E2 (zeige NFE2 ELISA Kits) negatively regulates differentiation and apoptosis activation of human syncytiotrophoblast by modulating GCM1 acetylation and sumoylation.
Identify a novel cis (zeige CISH ELISA Kits)-acting sequence (-369 to -320) at the placental growth factor (zeige PGF ELISA Kits) promoter, which was critical for mediating the basal and DLX3 (zeige DLX3 ELISA Kits)/GCM1-dependent PGF (zeige PGF ELISA Kits) promoter activities.
Twist1 (zeige TWIST1 ELISA Kits) may promote trophoblast syncytialization by regulating the expression of GCM1.
GATA3 (zeige GATA3 ELISA Kits) knockdown elevated HtrA4 (zeige HTRA4 ELISA Kits) expression in BeWo and JEG-3 trophoblast cell lines and enhanced the invasion activities of both lines. This study uncovered a new GATA3 (zeige GATA3 ELISA Kits) function in placenta as a negative regulator of GCM1 activity and trophoblastic invasion.
GLI2 (zeige GLI2 ELISA Kits) stabilized glial cell missing-a, a pivotal transcriptional factor for trophoblastic syncytialization.
Gcm1 and Fzd5 function in an evolutionary conserved positive feedback loop that regulates trophoblast differentiation and sites of chorionic branching morphogenesis.
Results suggest that caspase-14 (zeige CASP14 ELISA Kits) may interact with GCM1 to participate in syncytiotrophoblast differentiation during placental development.
study reveals a novel function for RACK1 (zeige GNB2L1 ELISA Kits) to regulate GCM1 activity and placental cell migration and invasion
GCM1-directed villous trophoblast differentiation is repressed by DREAM
c-Myc (zeige MYC ELISA Kits)-regulated members of the miR-17~92 and miR (zeige MLXIP ELISA Kits)-106a~363 clusters inhibit trophoblast differentiation by repressing GCM1 and CYP19A1 (zeige CYP19A1 ELISA Kits).
Data show that the GCM1/syncytin-B pathway is significantly downregulated in the placenta of BCL9L (zeige BCL9L ELISA Kits)-deficient mice and that the fusion and differentiation of ST-II cells are blocked.
as in mice, fetoplacental vascularity increased when GCM1 protein expression decreased (R(2)=-0.45; P<0.05).
Gcm1 (glial cells missing 1) are involved in the epigenetic regulation of Hes5 (zeige HES5 ELISA Kits) transcription by DNA demethylation independently of DNA replication.
studies identify a novel function of p45NF-E2 (zeige NFE2 ELISA Kits) during placental development: in trophoblast cells, p45NF-E2 (zeige NFE2 ELISA Kits) represses Gcm1 and syncytiotrophoblast formation via acetylation
Gcm1 expression defines three stages of chorio-allantoic interaction during placental development
Brief ectopic expression of Gcm1 in mouse embryonic tail bud induces failure of the neural tube to close (spina bifida) and multiple neural tubes (diastematomyelia).
GCM domain as a new type of Zn-coordinating, sequence-specific DNA-binding domain.
mGCMa expression is primarily postnatal, arguing for a role in organ function rather than organ development
the shaping of the maternal blood spaces within the labyrinth was dependent on chorioallantoic morphogenesis and therefore disrupted in Gcm1 mutants
This gene encodes a DNA-binding protein with a gcm-motif (glial cell missing motif). The encoded protein is a homolog of the Drosophila glial cells missing gene (gcm). This protein binds to the GCM-motif (A/G)CCCGCAT, a novel sequence among known targets of DNA-binding proteins. The N-terminal DNA-binding domain confers the unique DNA-binding activity of this protein.
glial cells missing homolog 1 (Drosophila)
, chorion-specific transcription factor GCMa
, glial cells missing-like protein 1
, glial cells missing homolog a
, chorion-specific transcription factor GCMa-like
, GCM motif protein 1
, Gcm 1
, Gcm a
, glial cell deficient