Gap Junction Protein, alpha 3, 46kDa (GJA3) ELISA Kits

The protein encoded by GJA3 is a connexin and is a component of lens fiber gap junctions. Zusätzlich bieten wir Ihnen Gap Junction Protein, alpha 3, 46kDa Antikörper (57) und Gap Junction Protein, alpha 3, 46kDa Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Maus GJA3 GJA3 14611 Q64448
Anti-Ratte GJA3 GJA3 79217 P29414
Anti-Human GJA3 GJA3 2700 Q9Y6H8
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Weitere ELISA Kits für Gap Junction Protein, alpha 3, 46kDa Interaktionspartner

Xenopus laevis Gap Junction Protein, alpha 3, 46kDa (GJA3) Interaktionspartner

  1. Data suggest that, in gap junctions of Xenopus oocytes, Cx50 (connexin 50 (zeige GJA8 ELISA Kits)) but not Cx46 (connexin 46) is regulated by phosphatidylinositol 3-kinase (PIK3C2A (zeige PIK3C2A ELISA Kits)) signaling pathway.

Zebrafish Gap Junction Protein, alpha 3, 46kDa (GJA3) Interaktionspartner

  1. Cx48.5, Cx44.1, Cx43 (zeige GJA1 ELISA Kits) have roles in lens development

  2. Connexin 48.5 has a role in normal cardiovascular function and lens development in zebrafish embryos

Mouse (Murine) Gap Junction Protein, alpha 3, 46kDa (GJA3) Interaktionspartner

  1. that expression and phosphorylation of connexin 46 and connexin 45 (zeige GJC1 ELISA Kits) are complementary in seminiferous tubules

  2. The localization and sizes of Cx50 (zeige GJA8 ELISA Kits) gap junction plaques in DKO fibers were unaffected, suggesting that Cx46 and Cx50 (zeige GJA8 ELISA Kits) form homomeric channels

  3. Data indicate that connexin 46 (cx46) is essential for the maintenance of adequate levels of glutathione (GSH) in the lens nucleus.

  4. Cx46 was severely reduced in both heterozygous and homozygous Cx46fs380 lenses at 1 month of age, whereas immunoreactive connexin50 (Cx50 (zeige GJA8 ELISA Kits)) was moderately decreased.

  5. Results suggest that Cx46 hemichannels may contribute to the sodium leak conductance in lens fiber cells.

  6. Data show that Ca(V) 1.2 and 1.3 channels are expressed in lens, regulating phosphorylation of aquaporin-0 and myosin light chain and expression of connexins 50 and 46.

  7. These results provide further evidence that Cx43 (zeige GJA1 ELISA Kits) and Cx46 form both heterotypic and heteromeric channels when co-expressed.

  8. nonspecific restoration of communication by Cx46 maintained differentiation of lens cells

  9. Results indicates connexin 46 expressed alone are recruited into different lipid environments and interaction of connexins and MP26 (zeige MIP ELISA Kits) contributes to the overall organization of the fiber cells.

Human Gap Junction Protein, alpha 3, 46kDa (GJA3) Interaktionspartner

  1. novel mutation in GJA3 for autosomal dominant congenital cataract

  2. The study identified a missense mutation (c. 176C>T) in GJA3 gene associated with autosomal dominant congenital pulverulent cataract in a Chinese family.

  3. in vivo results indicated that down-regulation of GJA3 in lens epithelial cells was associated with age-related cataract genesis. Data from this study established the association of GJA3 down regulation with lens epithelial cells apoptosis and age-related cataract genesis

  4. the role of the charged residues at the end of TM-1 in voltage sensing in Cx26 (zeige GJB2 ELISA Kits), Cx46, and Cx50 (zeige GJA8 ELISA Kits).

  5. Taken together, in Jar (zeige MYO6 ELISA Kits) cells, placental connexins 43 and 46 are regulated during periods of low oxygen in opposite manners

  6. A novel missense GJA3 mutation that correlated with congenital cataract phenotype in a five-generation Chinese family.

  7. This study identified three mutations in three Chinese families with hereditary cataracts. Of the three mutations, two were novel (c.125 A > C in GJA3 and c.268 C > T in GJA3), one was previously reported (c.218 C > T in GJA8 (zeige GJA8 ELISA Kits)).

  8. Glioblastoma cancer stem cells (CSCs) express Cx46, while Cx43 is predominantly expressed in non-CSCs. During differentiation, Cx46 is reduced, while Cx43 is increased, and targeting Cx46 compromises CSC maintenance

  9. A novel missense mutation, c.428G>A (p.G143E), in the GJA3 gene, localized to the cytoplasmic loop, was suggested to be the genetic cause of congenital nuclear cataract, which further expands the gene mutation spectrum.

  10. A novel GJA3 mutation (p.N55D) has been found in a Chinese family with congenital cataracts.

Cow (Bovine) Gap Junction Protein, alpha 3, 46kDa (GJA3) Interaktionspartner

  1. AQP-0 (zeige MIP ELISA Kits) and connexins can be segregated in the membrane by protein-lipid interactions as modified by AQP-0 (zeige MIP ELISA Kits) homo-oligomerization

Gap Junction Protein, alpha 3, 46kDa (GJA3) Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a connexin and is a component of lens fiber gap junctions. Defects in this gene are a cause of zonular pulverulent cataract type 3 (CZP3).

Genbezeichner und Symbole assoziert mit GJA3

  • MGC69466 protein L homeolog (MGC69466.L) Antikörper
  • gap junction protein alpha 3 (gja3) Antikörper
  • gap junction protein alpha 3 (GJA3) Antikörper
  • gap junction protein, alpha 3 (gja3) Antikörper
  • gap junction protein, alpha 3 (Gja3) Antikörper
  • Cnx46 Antikörper
  • CTRCT14 Antikörper
  • Cx43 Antikörper
  • Cx44 Antikörper
  • CX46 Antikörper
  • cx48.5 Antikörper
  • CZP3 Antikörper
  • Gja-3 Antikörper
  • MGC53082 Antikörper

Bezeichner auf Proteinebene für GJA3

gap junction protein, alpha 3, 46kDa , connexin 46 , alpha3 connexin , gap junction protein, alpha 3, 46kDa (connexin 46) , gap junction alpha-3 protein-like , connexin 48.5 , dco , dococ , gap junction alpha-3 protein , gap junction membrane channel protein alpha 3 , unm s215 , unm s226 , alpha 3 connexin , connexin-46 , cx46 , connexin-44 , cx44 , connexin-56 , cx56

GENE ID SPEZIES
379171 Xenopus laevis
100135710 Xenopus (Silurana) tropicalis
100225310 Taeniopygia guttata
467218 Pan troglodytes
486052 Canis lupus familiaris
704432 Macaca mulatta
100441955 Pongo abelii
387533 Danio rerio
14611 Mus musculus
79217 Rattus norvegicus
2700 Homo sapiens
100140301 Bos taurus
428084 Gallus gallus
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