anti-GTP Binding Protein 3 (Mitochondrial) (GTPBP3) Antikörper

This locus encodes a GTP-binding protein. Zusätzlich bieten wir Ihnen GTPBP3 Proteine (5) und GTPBP3 Kits (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
GTPBP3 290633 Q5PQQ1
GTPBP3 70359 Q923K4
GTPBP3 84705 Q969Y2
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Top anti-GTPBP3 Antikörper auf antikoerper-online.de

Showing 10 out of 33 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB GTPBP3 Antibody (Center) (ABIN1881398) western blot analysis in NCI-H460 cell line lysates (35 µg/lane). This demonstrates the GTPBP3 antibody detected the GTPBP3 protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: GTPBP3 Antibody [NBP1-91974] - Staining of human colon shows strong cytoplasmic positivity in glandular cells. Western Blot: GTPBP3 Antibody [NBP1-91974] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Human cell line RT-4 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Western Blot: GTPBP3 Antibody [NBP2-16765] - A: IMR32 Immunohistochemistry-Paraffin: GTPBP3 Antibody [NBP2-16765] - Human brain. 0.1 mL Anmelden zum Anzeigen 3 bis 6 Tage
341,00 €
Details
Human Kaninchen Unkonjugiert IHC   0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
288,10 €
Details
Human Maus Unkonjugiert ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL Anmelden zum Anzeigen 7 bis 8 Tage
241,60 €
Details
Human Kaninchen Unkonjugiert WB Western blot analysis in NCI-H460 cell line lysates (35ug/lane). 400 μL Anmelden zum Anzeigen 6 bis 8 Tage
538,22 €
Details
Human Kaninchen Unkonjugiert ELISA, WB   200 μL Anmelden zum Anzeigen 11 bis 14 Tage
941,11 €
Details
Human Kaninchen PE ELISA, WB   200 μL Anmelden zum Anzeigen 11 bis 14 Tage
1.203,02 €
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Human Kaninchen Alkaline Phosphatase (AP) ELISA, WB   200 μL Anmelden zum Anzeigen 11 bis 14 Tage
1.203,02 €
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Human Kaninchen Biotin ELISA, WB   200 μL Anmelden zum Anzeigen 11 bis 14 Tage
1.203,02 €
Details

GTPBP3 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Rat (Rattus)


Mouse (Murine)


Human ,
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Am meisten referenzierte anti-GTPBP3 Antikörper

  1. Human Polyclonal GTPBP3 Primary Antibody für WB - ABIN1881398 : Villarroya, Prado, Esteve, Soriano, Aguado, Pérez-Martínez, Martínez-Ferrandis, Yim, Victor, Cebolla, Montaner, Knecht, Armengod: Characterization of human GTPBP3, a GTP-binding protein involved in mitochondrial tRNA modification. in Molecular and cellular biology 2008 (PubMed)
    Show all 5 Pubmed References

  2. Human Polyclonal GTPBP3 Primary Antibody für IHC - ABIN966243 : Li, Guan: A human mitochondrial GTP binding protein related to tRNA modification may modulate phenotypic expression of the deafness-associated mitochondrial 12S rRNA mutation. in Molecular and cellular biology 2002 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal GTPBP3 Primary Antibody für ICC, IF - ABIN4316447 : Kopajtich, Nicholls, Rorbach, Metodiev, Freisinger, Mandel, Vanlander, Ghezzi, Carrozzo, Taylor, Marquard, Murayama, Wieland, Schwarzmayr, Mayr, Pearce, Powell, Saada, Ohtake, Invernizzi, Lamantea et al.: Mutations in GTPBP3 cause a mitochondrial translation defect associated with hypertrophic cardiomyopathy, lactic acidosis, and encephalopathy. ... in American journal of human genetics 2014 (PubMed)

Weitere Antikörper gegen GTPBP3 Interaktionspartner

Zebrafish GTP Binding Protein 3 (Mitochondrial) (GTPBP3) Interaktionspartner

  1. defective expression of gtpbp3 related to tRNA modification alters the mitochondrial function and development of zebrafish

Mouse (Murine) GTP Binding Protein 3 (Mitochondrial) (GTPBP3) Interaktionspartner

  1. These observations suggest that the mouse Gtpbp3 is an evolutionarily conserved mitochondrial GTP-binding protein involved in the tRNA modification.

Human GTP Binding Protein 3 (Mitochondrial) (GTPBP3) Interaktionspartner

  1. GTPBP3 defective expression is associated with an mitochondrial-tRNA hypomodification status.GTPBP3 plays a role in the regulation of UCP2 (zeige UCP2 Antikörper) and MCP1 (zeige CCL2 Antikörper) proteins through AMPK (zeige PRKAA1 Antikörper) signaling.

  2. Results show that post-transcriptional expression of GTPBP3, MTO1 and TRMU (zeige TRMU Antikörper) genes is down-regulated, leading to mt-tRNA hypomodification and contributing to mitochondrial dysfunction in MELAS cybrids.

  3. Most individuals with GTPBP3 mutations developed neurological symptoms and MRI (zeige C7ORF49 Antikörper) involvement of thalamus, putamen, and brainstem resembling Leigh syndrome.

  4. GTPBP3 localizes in the mitochondria and is a deafness-associated homolog of yeast MSS1.

  5. Phenotype of non-syndromic deafness associated with the mitochondrial A1555G mutation is modulated by mitochondrial RNA modifying enzymes MTO1 and GTPBP3.

  6. Data show that the two most abundant GTPBP3 isoforms exhibit moderate affinity for guanine nucleotides like their bacterial homologue, MnmE, although they hydrolyze GTP (zeige AK3 Antikörper) at a 100-fold lower rate.

GTPBP3 Antigen-Profil

Protein Überblick

This locus encodes a GTP-binding protein. The encoded protein is localized to the mitochondria and may play a role in mitochondrial tRNA modification. Polymorphisms at this locus may be associated with severity of aminoglycoside-induced deafness, a disease associated with a mutation in the 12S rRNA. Alternatively spliced transcript variants encoding different isoforms have been described.

Genbezeichner und Symbole assoziert mit GTPBP3

  • GTP binding protein 3 (mitochondrial) (GTPBP3) Antikörper
  • GTP binding protein 3 (Gtpbp3) Antikörper
  • GTP binding protein 3 (gtpbp3) Antikörper
  • 2410009F13Rik Antikörper
  • AI607903 Antikörper
  • GTPBG3 Antikörper
  • GTPBP3 Antikörper
  • MSS1 Antikörper
  • MTGP1 Antikörper
  • THDF1 Antikörper
  • zgc:112394 Antikörper

Bezeichner auf Proteinebene für GTPBP3

GTP binding protein 3 (mitochondrial) , tRNA modification GTPase GTPBP3, mitochondrial , tRNA modification GTPase GTPBP3, mitochondrial-like , GTP-binding protein 3 , mitochondrial GTP-binding protein 1

GENE ID SPEZIES
484838 Canis lupus familiaris
539656 Bos taurus
100070158 Equus caballus
100392904 Callithrix jacchus
100474937 Ailuropoda melanoleuca
290633 Rattus norvegicus
553807 Danio rerio
70359 Mus musculus
84705 Homo sapiens
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