GRB2-Associated Binding Protein 3 Proteine (GAB3)

GAB3 is a member of the GRB2-associated binding protein gene family. Zusätzlich bieten wir Ihnen GAB3 Antikörper (31) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
GAB3 139716 Q8WWW8
GAB3 210710 Q8BSM5
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Showing 6 out of 6 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
640,00 €
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HOST_Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 7 bis 8 Tage
235,20 €
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HOST_Escherichia coli (E. coli) Maus T7 tag,His tag   100 μg Anmelden zum Anzeigen 13 bis 17 Tage
713,33 €
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HOST_Escherichia coli (E. coli) Human Unkonjugiert   100 μg Anmelden zum Anzeigen 7 bis 14 Tage
818,45 €
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GAB3 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine) ,
,

Weitere Proteine zu GRB2-Associated Binding Protein 3 (GAB3) Interaktionspartnern

Human GRB2-Associated Binding Protein 3 (GAB3) Interaktionspartner

  1. we conclude that Gab3 overexpression in human glioma mediates Akt (zeige AKT1 Proteine) activation and cancer cell proliferation

  2. Together, our results suggest that Gab3 expression in CRC (zeige CALR Proteine) cells is important for Akt (zeige AKT1 Proteine)-Erk (zeige EPHB2 Proteine) activation and cell proliferation.

  3. The carboxy-terminal SH3 domain of the adapter prot (zeige GRAP2 Proteine)ein Mona interacts with the atypical proline-rich domain of Gab3 to mediate late signaling of the macrophage colony-stimulating factor receptor.

  4. Hematopoiesis in mice lacking Gab3 is not impaired, macrophages develop in normal numbers and exhibit normal function, and there is no major immune deficiency in T- and B-lymphocyte responses to protein antigens or during viral infection.

Mouse (Murine) GRB2-Associated Binding Protein 3 (GAB3) Interaktionspartner

  1. Induced expression and association of the Mona/Gads (zeige GRAP2 Proteine) adapter and Gab3 scaffolding protein during monocyte/macrophage differentiation. (Gab3 scaffolding protein)

  2. Gab3-deficient mice exhibit normal development and hematopoiesis and are immunocompetent

GAB3 Protein Überblick

Protein Überblick

This gene is a member of the GRB2-associated binding protein gene family. These proteins are scaffolding/docking proteins that are involved in several growth factor and cytokine signaling pathways, and they contain a pleckstrin homology domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. The protein encoded by this gene facilitates macrophage differentiation. Two transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit GAB3

  • GRB2-associated binding protein 3 (GAB3)
  • GRB2-associated binding protein 3 (gab3)
  • growth factor receptor bound protein 2-associated protein 3 (Gab3)
  • 5930433H21Rik Protein

Bezeichner auf Proteinebene für GAB3

GRB2-associated binding protein 3 , GRB2-associated-binding protein 3 , growth factor receptor bound protein 2-associated protein 3 , DOS/Gab family member 3 , GRB2-associated binder 3 , Gab3 scaffolding protein

GENE ID SPEZIES
428717 Gallus gallus
473837 Pan troglodytes
701859 Macaca mulatta
100063152 Equus caballus
100328766 Oryctolagus cuniculus
100453438 Pongo abelii
100474423 Ailuropoda melanoleuca
100554434 Anolis carolinensis
100603503 Nomascus leucogenys
139716 Homo sapiens
492262 Canis lupus familiaris
100518409 Sus scrofa
512009 Bos taurus
210710 Mus musculus
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