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anti-G Protein-Coupled Receptor 143 (GPR143) Antikörper

GPR143 encodes a protein that binds to heterotrimeric G proteins and is targeted to melanosomes in pigment cells. Zusätzlich bieten wir Ihnen G Protein-Coupled Receptor 143 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
GPR143 4935 P51810
GPR143 18241 P70259
GPR143 302619  
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Top anti-G Protein-Coupled Receptor 143 Antikörper auf antikoerper-online.de

Showing 10 out of 42 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IF, ELISA Immunofluorescence analysis of LOVO cells, using GPR143 Antibody. The ... 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
314,29 €
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Human Kaninchen Unkonjugiert IF, ELISA 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
565,71 €
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of GPR143 expression in A549 (A), NS-1 (B), PC12... 200 μL Anmelden zum Anzeigen 7 bis 8 Tage
464,29 €
Details
Human Kaninchen Unkonjugiert IHC (p) Anti-GPR143 antibody  ABIN1048724 IHC staining of human eye, retina. I... 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
501,70 €
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Human Kaninchen Unkonjugiert IF, ELISA 100 μg Anmelden zum Anzeigen 15 bis 21 Tage
419,39 €
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Human Kaninchen Unkonjugiert ELISA, WB 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
460,95 €
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Human Kaninchen Unkonjugiert ELISA, WB TheGPR143 Antibody is used in Western blot to detect GPR142 in HeLa ce... 0.1 mg Anmelden zum Anzeigen 6 bis 11 Tage
410,67 €
Details
Human Maus Unkonjugiert FACS, WB Western Blot analysis of GPR143 expression in transfected 293T cell li... FACS analysis of negative control 293 cells (Black) and GPR143 express... 50 μL Anmelden zum Anzeigen 8 bis 9 Tage
369,60 €
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Human Kaninchen Unkonjugiert WB   500 μg Anmelden zum Anzeigen 11 bis 14 Tage
583,17 €
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Human Kaninchen Unkonjugiert IHC, WB   500 μg Anmelden zum Anzeigen 7 bis 8 Tage
433,02 €
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GPR143 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Human , , , ,
,
Mouse (Murine) , , , ,

Rat (Rattus) , ,

Am meisten referenzierte anti-G Protein-Coupled Receptor 143 Antikörper

  1. Human Polyclonal GPR143 Primary Antibody für IHC, WB - ABIN350534 : Basrur, Yang, Kushimoto, Higashimoto, Yasumoto, Valencia, Muller, Vieira, Watabe, Shabanowitz, Hearing, Hunt, Appella: Proteomic analysis of early melanosomes: identification of novel melanosomal proteins. in Journal of proteome research 2003 (PubMed)
    Zeige alle 8 Referenzen für ABIN350534

  2. Human Polyclonal GPR143 Primary Antibody für IF, ELISA - ABIN1535711 : Ross, Grafham, Coffey, Scherer, McLay, Muzny, Platzer, Howell, Burrows, Bird, Frankish, Lovell, Howe, Ashurst, Fulton, Sudbrak, Wen, Jones, Hurles, Andrews, Scott, Searle, Ramser, Whittaker, Deadman et al.: The DNA sequence of the human X chromosome. ... in Nature 2005 (PubMed)

Weitere Antikörper gegen G Protein-Coupled Receptor 143 Interaktionspartner

Human G Protein-Coupled Receptor 143 (GPR143) Interaktionspartner

  1. Five mutations in GPR143 gene were detected in each of the five families, including a novel nonsense mutation of c.333G>A,two novel splicing mutations of c.360+1G>C and c.659-1G>A, a novel small deletion mutation of c.43_50dupGACGCAGC.

  2. intronic mutation that creates a cryptic splice-donor site in GPR143 of patients with ocular albinism

  3. The GPR143 gene analysis identified an identical point mutation in two Ocular albinism 1 patients and their mothers .

  4. Melanosome-autonomous regulation of size and number: the OA1 receptor sustains PMEL (zeige PMEL Antikörper) expression.

  5. OA1 is involved in melanoma cell migration and that OA1induced melanoma cell migration is mediated through the RAS/RAF (zeige RAF1 Antikörper)/MEK (zeige MAP2K1 Antikörper)/ERK (zeige EPHB2 Antikörper) signaling pathway.

  6. a novel splicing site mutation of the GPR143 gene was found in a Han Chinese congenital ocular albinism pedigree.

  7. Data report that p.Y269X mutation of GPR143 gene is responsible for the pathogenesis of familial ocular albinism.

  8. These results identify the Oa1 transducer Galphai3 (zeige GNAI3 Antikörper) as the first downstream component in the Oa1 signaling pathway.

  9. The ocular albinism type 1 (OA1) GPCR is ubiquitinated and its traffic requires endosomal sorting complex responsible for transport (ESCRT) function.

  10. TYR gene mutations have a more severe effect on pigmentation than mutations in OCA2 and the GPR143 gene. Nevertheless, mutations in these genes affect the development of visual function either directly or by interaction with other genes like MC1R.

Mouse (Murine) G Protein-Coupled Receptor 143 (GPR143) Interaktionspartner

  1. OA1 expression in both neuronal and non-neuronal tissues was examined by immunohistochemical analyses, results suggested that OA1 may modulate the monoaminergic functions in both peripheral and central nervous systems

  2. Melanosome-autonomous regulation of size and number: the OA1 receptor sustains PMEL (zeige PMEL Antikörper) expression.

  3. These results identify the Oa1 transducer Galphai3 (zeige GNAI3 Antikörper) as the first downstream component in the Oa1 signaling pathway.

  4. OA1 interacts with MART-1 (zeige RTL1 Antikörper) at early stages of melanogenesis to control melanosome identity and composition.

  5. Asparagine at amino acid 106 is essential for N-glycosylation of the Oa1 protein. Mutation at amino acid 106 that eliminated glycosylation did not affect the endo/lysosomal distribution of Oa1 protein in cells.

  6. the ocular albinism type 1 gene expression is controlled by microphthalmia transcription factor (Mitf (zeige MITF Antikörper))

  7. The findings indicate that Oa1 is involved in the regulation of melanosome maturation at two steps, Oa1 controls the abundance of melanosomes in RPE (zeige RPE Antikörper) cells and has a function in the maintenance of a correct melanosomal size.

  8. G alpha i3, like Oa1, plays important role in melanosome biogenesis. Common Oa1-G alpha i3 signaling pathway may ultimately affect axonal growth through optic chiasm.

  9. data point to defective regulation of organelle transport in pigment cells in absence of OA1; results enlighten novel function for OA1 in pigment cells & suggest ocular albinism type 1 may result from a different mechanism than previously thought

G Protein-Coupled Receptor 143 (GPR143) Antigen-Profil

Protein Überblick

This gene encodes a protein that binds to heterotrimeric G proteins and is targeted to melanosomes in pigment cells. This protein is thought to be involved in intracellular signal transduction mechanisms. Mutations in this gene cause ocular albinism type 1, also referred to as Nettleship-Falls type ocular albinism, a severe visual disorder. A related pseudogene has been identified on chromosome Y.

Genbezeichner und Symbole assoziert mit GPR143

  • G protein-coupled receptor 143 (GPR143) Antikörper
  • G protein-coupled receptor 143 (Gpr143) Antikörper
  • NYS6 Antikörper
  • Oa1 Antikörper
  • RGD1565799 Antikörper

Bezeichner auf Proteinebene für GPR143

G-protein coupled receptor 143 , ocular albinism type 1 protein , MOA1 , homolog of human ocular albinism 1 (Nettleship-Falls) , ocular albinism type 1 protein homolog

GENE ID SPEZIES
4935 Homo sapiens
18241 Mus musculus
302619 Rattus norvegicus
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