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GPRC5A encodes a member of the type 3 G protein-coupling receptor family, characterized by the signature 7-transmembrane domain motif. Zusätzlich bieten wir Ihnen GPRC5A Kits (25) und GPRC5A Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 121 products:
Human Polyclonal GPRC5A Primary Antibody für ICC, IF - ABIN4315891
Jahny, Yang, Liu, Jahnke, Lademann, Knösel, Rümmele, Grützmann, Aust, Pilarsky, Denz: The G Protein-Coupled Receptor RAI3 Is an Independent Prognostic Factor for Pancreatic Cancer Survival and Regulates Proliferation via STAT3 Phosphorylation. in PLoS ONE 2017
GPRC5A is a potential oncogene (zeige RAB1A Antikörper) in pancreatic ductal adenocarcinoma cells that is upregulated by gemcitabine with help from HuR (zeige ELAVL1 Antikörper).
These results suggest RAI3 plays an important role in adipogenesis of hASCs and may have a potential use in the future application.
Study underscores genomic alterations that represent early events in the development of Kras mutant LUAD following Gprc5a loss and tobacco carcinogen exposure.
Data show that G protein-coupled receptor (zeige ADRA1A Antikörper), family C, group 5, member A (zeige CXCL14 Antikörper) protein (GPRC5A) regulates oxidative stress through vanin 1 (zeige VNN1 Antikörper) protein (VNN1 (zeige VNN1 Antikörper)).
Suppression of GPRC5a results in decreased cell growth, proliferation and migration in pancreatic cancer cell lines via a STAT3 (zeige STAT3 Antikörper) modulated pathway, independent from ERK (zeige EPHB2 Antikörper) activation
our results implicate GPRC5A as a tumor suppressor in breast cancer cells, and GPRC5A exerts its tumor-suppressive function by inhibiting EGFR (zeige EGFR Antikörper) and its downstream pathway
elevated levels of GPRC5A played significant roles in gastric cancer progression
Results show how GPRC5A deficiency leads to dysregulated EGFR (zeige EGFR Antikörper) and STAT3 (zeige STAT3 Antikörper) signaling and lung tumorigenesis.
EGFR (zeige EGFR Antikörper) interacted with GPRC5A and phosphorylated it in two conserved double-tyrosine motifs, Y317/Y320 and Y347/ Y350, at the C-terminal tail of GPRC5A.
The interaction of miR (zeige MLXIP Antikörper)-103a-3p with each of the two 5' UTR (zeige UTS2R Antikörper) targets reduces the expression levels of both GPRC5A mRNA and GPRC5A protein in one normal epithelial and two pancreatic cancer cell lines.
Data show that G protein-coupled receptor (zeige GPR34 Antikörper), family C, group 5, member A (zeige CXCL14 Antikörper) protein (Gprc5a) deficiency exacerbates the silica-induced tissue damages and fibrogenic response in lungs.
Gprc5a deficiency leads to impaired induction of peripherally derived regulatory T-cells and increased experimental autoimmune encephalomyelitis severity.
Gprc5a deficiency confers susceptibility to endotoxin-induced pulmonary edema and injury, mainly through NF-kappaB (zeige NFKB1 Antikörper) signaling in bronchioalveolar epithelium of lung.
Gprc5a deletion enhances the transformed phenotype in normal and malignant lung epithelial cells by eliciting persistent Stat3 (zeige STAT3 Antikörper) signaling induced by autocrine leukemia inhibitory factor (zeige LIF Antikörper).
Loss of GPRC5A is associated with lung adenocarcinomas.
Gprc5a loss enhances NF-kappaB (zeige NFKB1 Antikörper) activation in lung epithelial cells
analysis of the Rai3 gene promoter revealed that the proximal region harbors most of the elements necessary for its regulation, including GC boxes and Sp1 (zeige SP1 Antikörper)-, AP1 (zeige JUN Antikörper)-, and AP2 (zeige TFAP2A Antikörper)-binding sites, and a retinoic acid response element
Data show that targeted inactivation of Raig1 did not cause significant developmental defects, and tha epithelial cell differentiation was normal and lung structure was intact.
This gene encodes a member of the type 3 G protein-coupling receptor family, characterized by the signature 7-transmembrane domain motif. The encoded protein may be involved in interaction between retinoid acid and G protein signalling pathways. Retinoic acid plays a critical role in development, cellular growth, and differentiation. This gene may play a role in embryonic development and epithelial cell differentiation.
G-protein coupled receptor family C group 5 member A
, orphan G-protein-coupling receptor PEIG-1
, retinoic acid induced 3
, retinoic acid responsive
, retinoic acid-induced gene 1 protein
, retinoic acid-induced protein 3