anti-G Protein Pathway Suppressor 2 (GPS2) Antikörper

GPS2 encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. Zusätzlich bieten wir Ihnen GPS2 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
GPS2 2874 Q13227
GPS2 56310  
GPS2 497941  
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Top anti-GPS2 Antikörper auf antikoerper-online.de

Showing 10 out of 74 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Maus Unkonjugiert EIA, WB 0.1 mL Anmelden zum Anzeigen 6 bis 8 Tage
$412.50
Details
Human Maus Unkonjugiert ELISA, FACS, WB Western Blot: GPS2 Antibody (1E2) [NBP1-22958] - Cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human GPS2 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Lane 1. : HeLa cell lysate Lane 2. : A431 cell lysate 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$381.94
Details
Human Kaninchen Unkonjugiert IHC, WB Western blot analysis of extracts of PC-3 cells, using GPS2 antibody. 100 μL Anmelden zum Anzeigen 16 Days
$460.63
Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μL Anmelden zum Anzeigen 16 Days
$175.80
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from RAW264.7 cells, using GPS2 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Maus Unkonjugiert ELISA, WB Detection limit for recombinant GST tagged GPS2 is approximately 0.3ng/ml as a capture antibody. Western Blot analysis of GPS2 expression in transfected 293T cell line by GPS2 monoclonal antibody (M01), clone 3C4.<br><br>Lane 1: GPS2 transfected lysate (Predicted MW: 36.7 KDa).<br>Lane 2: Non-transfected lysate.<br> 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$430.00
Details
Human Maus Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$478.50
Details
Human Maus Unkonjugiert WB Detection limit for recombinant GST tagged GPS2 is approximately 0.3 ng/mL as a capture antibody. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$450.00
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Western Blot: GPS2 Antibody [NBP2-14970] - Sample (30 ug of whole cell lysate) A: A431 B: HeLa 10% SDS PAGE, antibody diluted at 1:500. Immunohistochemistry-Paraffin: GPS2 Antibody [NBP2-14970] - Paraffin-embedded Gastric ca, using antibody at 1:500 dilution. 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage
$447.56
Details

GPS2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-GPS2 Antikörper

  1. Human Monoclonal GPS2 Primary Antibody für ELISA, WB - ABIN561119 : Sanyal, Båvner, Haroniti, Nilsson, Lundåsen, Rehnmark, Witt, Einarsson, Talianidis, Gustafsson, Treuter: Involvement of corepressor complex subunit GPS2 in transcriptional pathways governing human bile acid biosynthesis. in Proceedings of the National Academy of Sciences of the United States of America 2007 (PubMed)

Weitere Antikörper gegen GPS2 Interaktionspartner

Human G Protein Pathway Suppressor 2 (GPS2) Interaktionspartner

  1. The study of adipose tissue from humans with and without obesity revealed correlations between reduced GPS2 expression in macrophages, elevated systemic and adipose tissue inflammation, and diabetic status.

  2. our studies identify GPS2 functions as a tumor suppressor in LPS (zeige IRF6 Antikörper) and its downregulation is correlated to prognosis of LPS (zeige IRF6 Antikörper).

  3. Posttranslational modification of GPS2 by SUMOylation may serve as a key factor that regulates the function of GPS2 in vivo.

  4. regulation of GPS2 by posttranslational modifications provides an effective strategy for modulating its molecular function within the nuclear compartment.

  5. Chromosomal translocation in a pediatric undifferentiated spindle cell sarcoma have characterized this alteration to show rearrangement of the MLL4 (zeige MLL2 Antikörper) and GPS2 genes, resulting in fusion gene MLL4 (zeige MLL2 Antikörper)-GPS2, the expression of which promotes independent growth.

  6. GPS2 is required for the association of viral NS5A with VAP-A (zeige VAPA Antikörper) and hepatitis C virus replication.

  7. expression of the transcriptional corepressor complex subunits GPS2 and SMRT was significantly reduced in obese adipose tissue, inversely correlated to inflammatory status

  8. Results show for the first time that GPS-2 is differentially methylated at a site that lacks known methylation motifs and that the methylation state is detected by the immune system

  9. metabolically important coregulator GPS2 functions as a hitherto unrecognized transrepression mediator of interactions between SUMOylated nuclear receptors and the N-CoR (zeige NCOR1 Antikörper) corepressor complex

  10. Results show that the N-CoR (zeige NCOR1 Antikörper)-HDAC3 (zeige HDAC3 Antikörper) complex inhibits JNK (zeige MAPK8 Antikörper) activation through the associated GPS2 subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP-1 (zeige FOSB Antikörper) function.

Mouse (Murine) G Protein Pathway Suppressor 2 (GPS2) Interaktionspartner

  1. In macrophage-specific Gps2-knockout mice, inappropriate co-repressor complex function caused enhancer activation, pro-inflammatory gene expression and hypersensitivity toward metabolic-stress signals. By contrast, transplantation of GPS2-overexpressing bone marrow into two mouse models of obesity (ob/ob and diet-induced obesity) reduced inflammation and improved insulin (zeige INS Antikörper) sensitivity.

  2. GPS2 is required for restricting the activation of TLR and BCR (zeige BCR Antikörper) signaling pathways and the AKT (zeige AKT1 Antikörper)/FOXO1 (zeige FOXO1 Antikörper) pathway in immune cells based on direct inhibition of Ubc13 (zeige UBE2N Antikörper) enzymatic activity

  3. GPS2 stabilizes KDM4A (zeige KDM4A Antikörper) on target promoters by inhibiting Ubc13 (zeige UBE2N Antikörper)/RNF8 (zeige RNF8 Antikörper) ubiquitination.

  4. GPS2 binds to active PPARgamma (zeige PPARG Antikörper), facilitates its repression by NCoR (zeige NCOR1 Antikörper), and is required for the optimal NCoR (zeige NCOR1 Antikörper) corepressor function for PPARgamma (zeige PPARG Antikörper).

  5. GPS2 as a molecular guardian required for precise control of inflammatory responses involved in immunity and homeostasis.

  6. metabolically important coregulator GPS2 functions as a hitherto unrecognized transrepression mediator of interactions between SUMOylated nuclear receptors and the N-CoR (zeige NCOR1 Antikörper) corepressor complex

GPS2 Antigen-Profil

Protein Überblick

This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.

Genbezeichner und Symbole assoziert mit GPS2

  • G protein pathway suppressor 2 (gps2) Antikörper
  • G protein pathway suppressor 2 (GPS2) Antikörper
  • G protein pathway suppressor 2 (Gps2) Antikörper
  • AI505953 Antikörper
  • AMF-1 Antikörper
  • GPS2 Antikörper
  • MGC63588 Antikörper
  • MGC68832 Antikörper
  • MGC133909 Antikörper
  • zgc:63588 Antikörper

Bezeichner auf Proteinebene für GPS2

G protein pathway suppressor 2 , G-protein pathway suppressor 2 , GPS-2

GENE ID SPEZIES
379878 Xenopus laevis
393948 Danio rerio
403370 Xenopus laevis
455229 Pan troglodytes
518494 Bos taurus
100135707 Xenopus (Silurana) tropicalis
100529005 Ictalurus punctatus
2874 Homo sapiens
56310 Mus musculus
497941 Rattus norvegicus
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