Fyn-Related Kinase Proteine (FRK)

The protein encoded by FRK belongs to the TYR family of protein kinases. Zusätzlich bieten wir Ihnen FRK Antikörper (162) und FRK Kits (6) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Ratte FRK FRK 25468 P63142
FRK 2444 P42685
FRK 14302 Q922K9
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Top FRK Proteine auf antikoerper-online.de

Showing 9 out of 12 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Baculovirus infected Insect Cells Human Unkonjugiert 5 μg Anmelden zum Anzeigen 2 bis 3 Tage
$295.00
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$7,759.50
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$7,759.50
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$405.71
Details
Insektenzellen Human His-GST   100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$1,372.00
Details
Baculovirus infected Insect Cells Human GST tag   5 μg Anmelden zum Anzeigen 10 bis 12 Tage
$322.08
Details
Insektenzellen Human GST tag   10 μg Anmelden zum Anzeigen 3 bis 4 Tage
$310.00
Details
Escherichia coli (E. coli) Human T7 tag,His tag   100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$704.00
Details
Sf-9 cells Human Unkonjugiert   5 μg Anmelden zum Anzeigen 2 bis 3 Tage
$510.36
Details

FRK Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , ,
, , ,
Mouse (Murine)

Weitere Proteine zu Fyn-Related Kinase (FRK) Interaktionspartnern

Human Fyn-Related Kinase (FRK) Interaktionspartner

  1. our results present the first evidence that site-specific promoter methylation contributes to the repression of FRK more so in basal B breast cancers.

  2. Loss of FRK protein may be implicated into the tumorigenesis and cell motility/invasiveness of human cervical cancer.

  3. antagomir-1290 significantly inhibited the proliferation, clonogenicity, invasion, and migration of CD133(+) cells by targeting fyn (zeige FYN Proteine)-related Src (zeige SRC Proteine) family tyrosine kinase (zeige TXK Proteine).

  4. our results demonstrate a combined mechanism for the anti-proliferative effects of FRK by inhibiting cyclin D1 (zeige CCND1 Proteine) nucleus accumulation and pRb (zeige RB1 Proteine) phosphorylation in glioma cells.

  5. FRK over-expression promoted beta-catenin (zeige CTNNB1 Proteine) translocation to the plasma membrane, where it formed complex with N-cadherin (zeige CDH2 Proteine).

  6. exome sequencing identified recurrent somatic FRK mutations that induce constitutive kinase activity, STAT3 (zeige STAT3 Proteine) activation, and cell proliferation sensitive to Src (zeige SRC Proteine) inhibitors

  7. Data indicaate that the Rak/Frk SH2 and SH3 domains collaborate to increase the Rak-EGFR (zeige EGFR Proteine) interaction.

  8. The expression levels of FRK were significantly correlated with invasiveness in both Hep3B and HepG2 tumor cell lines.

  9. these results clearly indicate that FRK may play a protective role against the progression of glioma by suppressing cell migration and invasion

  10. Genetic variation near FRK/COL10A1 (zeige COL10A1 Proteine) and VEGFA (zeige VEGFA Proteine) are associated with advanced age-related macular degeneration.

Mouse (Murine) Fyn-Related Kinase (FRK) Interaktionspartner

  1. Characterization of mice deficient in the Src (zeige SRC Proteine) family nonreceptor tyrosine kinase (zeige TYRO3 Proteine) Frk/rak. Decreases in the circulating levels of T3 but not T4 are reminiscent of euthyroid sick syndrome, a stress-associated clinical condition

  2. The tyrosine kinases Brk/PTK6/Sik (zeige PTK6 Proteine), Srm (zeige SRM Proteine), Frk/Rak/Gtk/Iyk/Bsk (zeige EPHA5 Proteine), and Src42A/Dsrc41 have a low degree of sequence homology to other known kinases. The exon structure of these kinases, called the Brk (zeige PTK6 Proteine) family, is highly conserved and distinct.

  3. Experiments with Fyn (zeige FYN Proteine)-deficient mice indicate that Fyn (zeige FYN Proteine) genotype does not influence ethanol consumption, neither under basal conditions nor following a deprivation period or stress.

  4. These results show that FRK affects beta cell number during embryogenesis and early in life, but is probably redundant for beta cell number and function in adult animals under normal conditions.

FRK Protein Überblick

Protein Überblick

The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth.

Genbezeichner und Symbole assoziert mit Fyn-Related Kinase Proteine (FRK)

  • potassium voltage-gated channel subfamily A member 2 (Kcna2)
  • Fyn-related kinase (FRK)
  • fyn related Src family tyrosine kinase (FRK)
  • fyn related Src family tyrosine kinase (frk)
  • tyrosine-protein kinase FRK (LOC100540680)
  • fyn-related kinase (Frk)
  • fyn-related Src family tyrosine kinase (Frk)
  • BK2 Protein
  • BSK Protein
  • BSK/IYK Protein
  • C85044 Protein
  • FRK Protein
  • GTK Protein
  • NGK1 Protein
  • PTK5 Protein
  • RAK Protein

Bezeichner auf Proteinebene für Fyn-Related Kinase Proteine (FRK)

Potassium (K+) channel protein alpha 2, voltage dependent , RAK , RBK2 , RCK5 , potassium voltage gated channel shaker related subfamily member 2 , potassium voltage-gated channel subfamily A member 2 , voltage-gated potassium channel subunit Kv1.2 , hypothetical protein LOC583550 , fyn-related kinase , tyrosine-protein kinase FRK-like , PTK5 protein tyrosine kinase 5 , nuclear tyrosine protein kinase RAK , protein-tyrosine kinase 5 , tyrosine-protein kinase FRK , B-cell src-homology tyrosine kinase , beta-cell Src-homology tyrosine kinase , intestine tyrosine kinase , GASK , GTK , gastrointestinal-associated kinase , gastrointestinal-associated tyrosine kinase , src related tyrosine kinase

GENE ID SPEZIES
25468 Rattus norvegicus
583550 Strongylocentrotus purpuratus
481970 Canis lupus familiaris
462953 Pan troglodytes
716267 Macaca mulatta
100403046 Callithrix jacchus
100448548 Pongo abelii
100488362 Xenopus (Silurana) tropicalis
100540680 Meleagris gallopavo
100593495 Nomascus leucogenys
2444 Homo sapiens
421747 Gallus gallus
509227 Bos taurus
14302 Mus musculus
79209 Rattus norvegicus
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