anti-Fanconi Anemia Group A Protein (FANCA) Antikörper

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). Zusätzlich bieten wir Ihnen Fanconi Anemia Group A Protein Proteine (4) und Fanconi Anemia Group A Protein Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
FANCA 2175 O15360
FANCA 14087 Q9JL70
FANCA 361435  
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Top anti-Fanconi Anemia Group A Protein Antikörper auf antikoerper-online.de

Showing 10 out of 113 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IF, IHC, ELISA, WB Western blot analysis of extracts from HeLa cells treated with IGF 100ng/ml 10' and HuvEc cells treated with EGF 200ng/ml 30', using FANCA (Phospho-Ser1149) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using FANCA (Phospho-Ser1149) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using FANCA (Ab-1149) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Schimpanse Kaninchen Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$450.34
Details
Human Kaninchen Unkonjugiert ELISA, WB   0.1 mg Anmelden zum Anzeigen 2 bis 6 Tage
$275.00
Details
Human Kaninchen Unkonjugiert WB Western Blot: FANCA Antibody [ABIN251002] - Detection of FANC A in transfected COS1 cell lysate using ABIN251002. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$345.00
Details
Human Kaninchen Unkonjugiert ELISA, ICC, IF, IHC, IHC (p), IP, WB Western Blot: FACA/FANCA Antibody [NBP1-03286] - Anti-FANCA Antibody - Western Blot. Western blot using affinity purified anti-FANCA antibody shows detection of a band at ~133 kD (arrowhead) corres-ponding to FANCA in HeLa whole cell lysates. The identity of the lower molecular weight bands is unknown but may represent breakdown products. Immunohistochemistry-Paraffin: FACA/FANCA Antibody [NBP1-03286] - Staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 0.05 mg Anmelden zum Anzeigen 10 bis 13 Tage
$556.31
Details
Human Kaninchen Unkonjugiert EIA, IHC (p) Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Uterus, Endometrium: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Anmelden zum Anzeigen 11 bis 13 Tage
$594.55
Details
Human Kaninchen Unkonjugiert ELISA, IF, IHC, WB 100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$500.50
Details

FANCA Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Fanconi Anemia Group A Protein Antikörper

  1. Polyclonal FANCA Primary Antibody für WB - ABIN540722 : Park, Ciccone, Beck, Hwang, Freie, Clapp, Lee: Oxidative stress/damage induces multimerization and interaction of Fanconi anemia proteins. in The Journal of biological chemistry 2004 (PubMed)

  2. Human Polyclonal FANCA Primary Antibody für ELISA, ICC - ABIN4309986 : Huard, Tremblay, Magron, Lévesque, Carreau: The Fanconi anemia pathway has a dual function in Dickkopf-1 transcriptional repression. in Proceedings of the National Academy of Sciences of the United States of America 2014 (PubMed)

Weitere Antikörper gegen Fanconi Anemia Group A Protein Interaktionspartner

Human Fanconi Anemia Group A Protein (FANCA) Interaktionspartner

  1. we show that although FANCA S1088F protein properly localizes to the nucleus, it alters FANC complex function, enhances sensitivity to DNA damaging agents, and sensitizes cells to PARP (zeige COL11A2 Antikörper) inhibitors in vitro and in vivo.

  2. FancA amplification and overexpression appear to be crucial for radiotherapeutic failure in head and neck squamous cell carcinomas.

  3. High resolution melting curve analysis was used to screen FANCA, and LinReg software version 1.7 was utilized for analysis of expression. RESULTS: In total, six sequence alterations were identified, which included two stop codons, two frames-shift mutations, one large deletion and one amino acid exchange. FANCA expression was downregulated in patients who had sequence alterations.

  4. Results identified homozygous mutations in FANCA and FANCP/SLX4 (zeige BTBD12 Antikörper) genes, both located on chromosome 16, were the affected recessive FA genes in three and one family respectively. Genotyping with short tandem repeat markers and SNP arrays revealed uniparental disomy of the entire mutation-carrying chromosome 16 in all four patients.

  5. Using human and murine cells defective in FANCD2 (zeige FANCD2 Antikörper) or FANCA and primary bone marrow cells derived from FANCD2 (zeige FANCD2 Antikörper) deficient mice, we show that the FA pathway removes R loops and that many DNA breaks accumulated in FA cells are R loop-dependent.

  6. FANCA safeguards interphase and mitosis during hematopoiesis

  7. The I939S point mutation prevented binding to the FAAP20 subunit of the FA core complex, caused SUMOylation at K921, RNF4 (zeige RNF4 Antikörper)-mediated polyubiquitination and degradation.

  8. A frameshifting mutation and a truncating mutation of FANCA are associated with Fanconi anemia (zeige PALB2 Antikörper).

  9. Proliferation is compromised in FANCA-deficient pluripotent embryonic stem cells.

  10. FANCA-modulated neddylation pathway involved in CXCR5 (zeige CXCR5 Antikörper) membrane targeting and cell mobility.

Mouse (Murine) Fanconi Anemia Group A Protein (FANCA) Interaktionspartner

  1. FANCA safeguards interphase and mitosis during hematopoiesis

  2. study indicates that Fanca expression during endomitosis is crucial for normal megakaryopoiesis and platelet production.

  3. Data show that Fanconi anemia complementation group A Fanca is required for the induction of transition mutations at A/T residues during somatic hypermutation (SHM (zeige CNTNAP1 Antikörper)) and immunoglobulin (Ig) class switch recombination (CSR (zeige SCARA3 Antikörper)).

  4. CD25 (zeige IL2RA Antikörper)(+)Foxp3 (zeige FOXP3 Antikörper)(+) Tregs of Fanca(-/-) or Fancd2 (zeige FANCD2 Antikörper)(-/-) mice were less efficient in suppressing the production of GVHD-associated inflammatory cytokines.

  5. null mutations in Fanca or Fancg (zeige FANCG Antikörper) are fully epistatic

  6. genetic diversity in FANCA, FANCC (zeige FANCC Antikörper) and FANCL (zeige FANCL Antikörper) does not support an association of these genes with cervical cancer susceptibility in the Swedish population.

  7. The results support a model where both FANCA and FANCC (zeige FANCC Antikörper) are part of a multi-protein nuclear FA complex with identical function in cellular responses to DNA damage and germ cell survival.

  8. To study the in vivo role of the FA group A gene (Fanca), gene-targeting techniques were used to generate Fanca(tm1Hsc) mice in which Fanca exons 1-6 were replaced by a beta (zeige SUCLA2 Antikörper)-galactosidase (zeige GLB1 Antikörper) reporter construct.

  9. GnRH (zeige GNRH1 Antikörper) induced a rapid, transient increase in Fanca mRNA.

  10. Fanca protein as an integral component in the early step of homologous repair of DNA double-strand brearks thereby minimizing the genomic instability.

Fanconi Anemia Group A Protein (FANCA) Antigen-Profil

Protein Überblick

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity\; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are the most common cause of Fanconi anemia.

Genbezeichner und Symbole assoziert mit FANCA

  • Fanconi anemia complementation group A (FANCA) Antikörper
  • Fanconi anemia, complementation group A (Fanca) Antikörper
  • AW208693 Antikörper
  • FA Antikörper
  • FA-H Antikörper
  • FA1 Antikörper
  • FAA Antikörper
  • FACA Antikörper
  • FAH Antikörper
  • FANCH Antikörper

Bezeichner auf Proteinebene für FANCA

Fanconi anemia group A protein , Fanconi anemia, complementation group H , Fanconi anemia, type 1 , Fanconi anemia group A protein homolog

GENE ID SPEZIES
2175 Homo sapiens
454393 Pan troglodytes
14087 Mus musculus
415854 Gallus gallus
361435 Rattus norvegicus
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