anti-FSHD Region Gene 1 (FRG1) Antikörper

FRG1 maps to a location 100 kb centromeric of the repeat units on chromosome 4q35 which are deleted in facioscapulohumeral muscular dystrophy (FSHD). Zusätzlich bieten wir Ihnen FSHD Region Gene 1 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
FRG1 361156  
FRG1 2483 Q14331
FRG1 14300 P97376
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Top anti-FSHD Region Gene 1 Antikörper auf antikoerper-online.de

Showing 10 out of 74 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-Frg1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Rat Liver 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of FRG1 Antibody (C-term) in ZR-75-1 cell line lysates (35ug/lane). This demonstrates the FRG1 antibody detected the FRG1 protein (arrow). 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Ziege Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$375.38
Details
Huhn Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert WB FRG1 Antibody (C-term)  western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the FRG1 antibody detected the FRG1 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Ziege Unkonjugiert ELISA Western Blot: FRG1 Antibody [NBP1-49864] (2ug/ml) staining of Jurkat nuclear lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$408.19
Details
Human Maus Unkonjugiert IF, WB Immunofluorescence of <u>purified</u> MaxPab antibody to FRG1 on HeLa cell. [antibody concentration 10 ug/ml] Western Blot analysis of FRG1 expression in transfected 293T cell line by FRG1 MaxPab polyclonal antibody.<br><br>Lane 1: FRG1 transfected lysate(28.38 KDa).<br>Lane 2: Non-transfected lysate.<br> 50 μL Anmelden zum Anzeigen 11 bis 12 Tage
$430.00
Details
Human Maus Unkonjugiert IF, IP, ELISA, WB FRG1 monoclonal antibody (M01), clone 4A5 Western Blot analysis of FRG1 expression in Hela S3 NE . Western Blot analysis of FRG1 expression in transfected 293T cell line by FRG1 monoclonal antibody (M01), clone 4A5.<br><br>Lane 1: FRG1 transfected lysate(29 KDa).<br>Lane 2: Non-transfected lysate.<br> 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$430.00
Details
Human Ziege Unkonjugiert ELISA, WB 0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$481.25
Details

FRG1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-FSHD Region Gene 1 Antikörper

  1. Human Polyclonal FRG1 Primary Antibody für ELISA - ABIN4272916 : Hanel, Wuebbles, Jones: Muscular dystrophy candidate gene FRG1 is critical for muscle development. in Developmental dynamics : an official publication of the American Association of Anatomists 2009 (PubMed)

  2. Human Polyclonal FRG1 Primary Antibody für IF, WB - ABIN515816 : Ferri, Huichalaf, Caccia, Gabellini: Direct interplay between two candidate genes in FSHD muscular dystrophy. in Human molecular genetics 2015 (PubMed)

  3. Human Monoclonal FRG1 Primary Antibody für IF, IP - ABIN560950 : Wallace, Garwick-Coppens, Tupler, Harper: RNA interference improves myopathic phenotypes in mice over-expressing FSHD region gene 1 (FRG1). in Molecular therapy : the journal of the American Society of Gene Therapy 2011 (PubMed)

Weitere Antikörper gegen FSHD Region Gene 1 Interaktionspartner

Human FSHD Region Gene 1 (FRG1) Interaktionspartner

  1. Our results demonstrate that FRG1 is a direct DUX4 transcriptional target uncovering a novel regulatory circuit contributing to Facioscapulohumeral muscular dystrophy.

  2. FRG1 mice overexpressing FHL1 (zeige FHL1 Antikörper) showed an improvement in the dystrophic phenotype

  3. This study suggests a novel role of FRG1 as epigenetic regulator of muscle differentiation and indicates that Suv4-20h1 (zeige SUV420H1 Antikörper) has a gene-specific function in myogenesis.

  4. depressed myoblast proliferation may contribute to the pathology of mice overexpressing FRG1 and may play a part in facioscapulohumeral muscular dystrophy

  5. These data provide the first biochemical activities (actin binding and RNA binding) for human FRG1 and the characterization of the endogenous human FRG1, together indicating that FRG1 is involved in multiple aspects of RNA biogenesis.

  6. in muscle FRG1 is a developmentally regulated sarcomeric protein suggesting FRG1 may perform a muscle-specific (zeige EIF3K Antikörper) function

  7. FRG1 transgenic mice develop a muscular dystrophy with features characteristic of the human disease; by contrast, FRG2 and ANT1 (zeige SLC25A4 Antikörper) transgenic mice seem normal

  8. differently from normal myoblasts, the 4qA/B marker interacted directly with the promoters of the FRG1 and ANT1 (zeige SLC25A4 Antikörper) genes in Facio-Scapulo-Humeral Dystrophy cells

  9. Data show that frg1 is expressed in and essential for the development of the tadpole musculature, and suggest that maintenance of normal FRG1 levels is critical for proper muscle development in frogs and humans.

  10. study compared chromatin structure & tridimensional interaction of the D4Z4 array and FRG1 gene promoter, and FRG1 expression, in control and FSHD cells

Mouse (Murine) FSHD Region Gene 1 (FRG1) Interaktionspartner

  1. FRG1 is involved in the morphogenesis of the tooth germ, as well as in the formation of enamel and dentin matrices and that FRG1 may play a role in the odontogenesis in the mouse following BMP4 (zeige BMP4 Antikörper) stimulation.

  2. Mouse Frg1 genomic area lacks DUX4 binding sites and DUX4 is unable to activate the endogenous mouse Frg1 gene providing a possible explanation for the lack of muscle phenotype in DUX4 transgenic mice.

  3. This study suggests a novel role of FRG1 as epigenetic regulator of muscle differentiation and indicates that Suv4-20h1 (zeige SUV420H1 Antikörper) has a gene-specific function in myogenesis.

  4. On the basis of these results, it was proposed that aberrant fTnT represents a biological marker of muscle phenotype severity and disease progression.

  5. our results suggest that a component of FSHD pathogenesis may arise by over-expression of FRG1, reducing Rbfox1 (zeige A2BP1 Antikörper) levels and leading to aberrant expression of an altered Calpain 3 (zeige CAPN3 Antikörper) protein through dysregulated splicing

FSHD Region Gene 1 (FRG1) Antigen-Profil

Protein Überblick

This gene maps to a location 100 kb centromeric of the repeat units on chromosome 4q35 which are deleted in facioscapulohumeral muscular dystrophy (FSHD). It is evolutionarily conserved and has related sequences on multiple human chromosomes but DNA sequence analysis did not reveal any homology to known genes. In vivo studies demonstrate the encoded protein is localized to the nucleolus.

Genbezeichner und Symbole assoziert mit FRG1

  • FSHD region gene 1-like (Frg1l) Antikörper
  • FSHD region gene 1 (FRG1) Antikörper
  • FSHD region gene 1 (frg1) Antikörper
  • FSHD region gene 1 (LOC100345738) Antikörper
  • FRG1 protein (frg1) Antikörper
  • FSHD region gene 1 (Frg1) Antikörper
  • frg1 Antikörper
  • FRG1A Antikörper
  • FSG1 Antikörper
  • MGC84293 Antikörper
  • MGC89908 Antikörper

Bezeichner auf Proteinebene für FRG1

FSHD region gene 1-like , FSHD region gene 1 , protein FRG1 , FSHD region gene 1 protein , facioscapulohumeral muscular dystrophy region gene-1

GENE ID SPEZIES
361156 Rattus norvegicus
422726 Gallus gallus
444679 Xenopus laevis
448726 Xenopus (Silurana) tropicalis
482899 Canis lupus familiaris
698743 Macaca mulatta
738279 Pan troglodytes
100345738 Oryctolagus cuniculus
445937 Takifugu rubripes
2483 Homo sapiens
14300 Mus musculus
689484 Rattus norvegicus
512533 Bos taurus
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