anti-F-Box and WD Repeat Domain Containing 8 (FBXW8) Antikörper

FBXW8 encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. Zusätzlich bieten wir Ihnen FBXW8 Kits (12) und FBXW8 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
FBXW8 26259 Q8N3Y1
FBXW8 304522  
FBXW8 231672 Q8BIA4
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Top anti-FBXW8 Antikörper auf antikoerper-online.de

Showing 10 out of 49 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-FBXW8 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB FBXW8 Antibody (Center) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. FBXW8 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FBXW8 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB FBXW8 Antibody (Center) (ABIN654676) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: FBXW8 Antibody [NBP1-84715] - Staining of human cell line A-431 shows positivity in vesicles. Immunohistochemistry-Paraffin: FBXW8 Antibody [NBP1-84715] - Staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells. 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
335,00 €
Details
Human Maus Unkonjugiert ELISA, WB FBXW8 polyclonal antibody (A01), Lot # UMI10060110QCS1 Western Blot analysis of FBXW8 expression in Hela NE Western Blot detection against Immunogen (37.11 KDa) . 50 μL Anmelden zum Anzeigen 7 bis 8 Tage
241,60 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
Details
Human Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
459,65 €
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB Western blot analysis in Hela cell line lysates (35ug/lane). Western blot analysis in mouse bladder tissue lysates (35ug/lane). 400 μL Anmelden zum Anzeigen 6 bis 8 Tage
538,22 €
Details
Human Kaninchen Unkonjugiert ELISA, FACS, IHC, WB   200 μL Anmelden zum Anzeigen 11 bis 14 Tage
941,11 €
Details

FBXW8 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-FBXW8 Antikörper

  1. Human Polyclonal FBXW8 Primary Antibody für ELISA, WB - ABIN565252 : Wei, Yang, Chuang, Yang, Kulp, Lu, Lai, Chen: A novel mechanism by which thiazolidinediones facilitate the proteasomal degradation of cyclin D1 in cancer cells. in The Journal of biological chemistry 2008 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal FBXW8 Primary Antibody für ICC, IF - ABIN4310808 : Halbach, Stehning, Damrath, Jendrach, Şen, Başak, Auburger: Both ubiquitin ligases FBXW8 and PARK2 are sequestrated into insolubility by ATXN2 PolyQ expansions, but only FBXW8 expression is dysregulated. in PLoS ONE 2015 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal FBXW8 Primary Antibody für FACS, IHC (p) - ABIN654676 : Wang, Chen, Lin, Li, Zhou, Liu, Logsdon, Jin, Abbruzzese, Tan, Wang: The CUL7/F-box and WD repeat domain containing 8 (CUL7/Fbxw8) ubiquitin ligase promotes degradation of hematopoietic progenitor kinase 1. in The Journal of biological chemistry 2014 (PubMed)

  4. Cow (Bovine) Polyclonal FBXW8 Primary Antibody für WB - ABIN2786275 : Tsutsumi, Kuwabara, Arai, Xiao, Decaprio: Disruption of the Fbxw8 gene results in pre- and postnatal growth retardation in mice. in Molecular and cellular biology 2008 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen FBXW8 Interaktionspartner

Human F-Box and WD Repeat Domain Containing 8 (FBXW8) Interaktionspartner

  1. FBXW8 and PARK2 (zeige PARK2 Antikörper) are sequestrated into insolubility by ATXN2 (zeige ATXN2 Antikörper) PolyQ expansions, but only FBXW8 expression is dysregulated

  2. findings will shed light the role to mechanism of miR (zeige MLXIP Antikörper)-218 in regulating JEG-3 cells proliferation via miR (zeige MLXIP Antikörper)-218/Fbxw8 axis, and miR (zeige MLXIP Antikörper)-218 may serve as a novel potential therapeutic target in human choriocarcinoma in the future

  3. CUL7 (zeige CUL7 Antikörper)/Fbxw8 ubiquitin ligase-mediated HPK1 (zeige MAP4K1 Antikörper) degradation revealed a direct link and novel role of CUL7 (zeige CUL7 Antikörper)/Fbxw8 ubiquitin ligase in the MAPK (zeige MAPK1 Antikörper) pathway, which plays a critical role in cell proliferation and differentiation.

  4. Dysregulation of Cul7 (zeige CUL7 Antikörper) and Fbxw8 expression might affect trophoblast turnover in intrauterine growth restriction.

  5. Growth factor-stimulated TBC1D3 (zeige TBC1D3 Antikörper) ubiquitination and degradation are regulated by its interaction with CUL7 (zeige CUL7 Antikörper)-Fbw8.

  6. Fbxw8 plays an essential role in the proliferation of human trophoblast cells, especially JEG-3 cells.

  7. FBXW8 plays an essential role in cancer cell proliferation throug (zeige CCND1 Antikörper)h proteolysis of cyclin D1. It may (zeige CDK1 Antikörper) present new opportunities to develop therapies targeting destruction of cyclin D1 or its regulator E3 ligase selectively.

  8. FBXW8-CUL7 (zeige CUL7 Antikörper) complex plays a significant role in growth control

Mouse (Murine) F-Box and WD Repeat Domain Containing 8 (FBXW8) Interaktionspartner

  1. FBXW8 and PARK2 (zeige PARK2 Antikörper) are sequestrated into insolubility by ATXN2 (zeige ATXN2 Antikörper) PolyQ expansions, but only FBXW8 expression is dysregulated

  2. mTORC2 (zeige CRTC2 Antikörper) negatively feeds back to IRS-1 (zeige IRS1 Antikörper) via control of Fbw8 stability and localization.

  3. our data support the concept that expanded ATXN2 (zeige ATXN2 Antikörper) undergoes progressive insolubility and affects PABPC1 (zeige PABPC1 Antikörper) by a toxic gain-of-function mechanism with tissue-specific effects, which may be partially alleviated by the induction of FBXW8.

  4. Depletion of FBXW8 caused a significant accumulation of cyclin D1 (zeige CCND1 Antikörper), as well as sequestration of CDK1 (zeige CDK1 Antikörper) in the cytoplasm. This resulted in a severe reduction of cell proliferation.

  5. Cul7 (zeige CUL7 Antikörper) forms a heterodimeric complex with Cul1 (zeige CUL1 Antikörper) in a manner dependent on Fbxw8.

  6. FBXW8-CUL7 (zeige CUL7 Antikörper) complex plays a significant role in growth control

FBXW8 Antigen-Profil

Protein Überblick

This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.

Genbezeichner und Symbole assoziert mit FBXW8

  • F-box and WD repeat domain containing 8 (FBXW8) Antikörper
  • F-box and WD repeat domain containing 8 (Fbxw8) Antikörper
  • F-box and WD-40 domain protein 8 (Fbxw8) Antikörper
  • 4930438M06Rik Antikörper
  • FBW6 Antikörper
  • FBW8 Antikörper
  • Fbx29 Antikörper
  • FBXO29 Antikörper
  • FBXW6 Antikörper

Bezeichner auf Proteinebene für FBXW8

F-box and WD-40 domain protein 8 , F-box and WD-40 domain-containing protein 8 , F-box only protein 29 , F-box/WD repeat-containing protein 8 , F-box protein FBX29

GENE ID SPEZIES
486288 Canis lupus familiaris
26259 Homo sapiens
787118 Bos taurus
304522 Rattus norvegicus
100728842 Cavia porcellus
101108081 Ovis aries
231672 Mus musculus
Ausgewählte Anbieter für anti-FBXW8 (FBXW8) Antikörper
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