F-Box Protein 4 (FBXO4) ELISA Kits

FBXO4 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. Zusätzlich bieten wir Ihnen F-Box Protein 4 Antikörper (90) und F-Box Protein 4 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
FBXO4 26272 Q9UKT5
FBXO4 106052 Q8CHQ0
FBXO4 310363  
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Top F-Box Protein 4 ELISA Kits auf antikoerper-online.de

Showing 10 out of 12 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.1 ng/mL 0.5-10 ng/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
Details
Ratte 0.1 ng/mL 0.5-10 ng/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
Details
Maus 0.1 ng/mL 0.5-10 ng/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
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Kaninchen
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
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Schwein
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
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Rind (Kuh)
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
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Ziege
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
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Meerschweinchen
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
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Hund
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
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Affe
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
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Weitere ELISA Kits für F-Box Protein 4 Interaktionspartner

Human F-Box Protein 4 (FBXO4) Interaktionspartner

  1. results define the impact of alternative splicing on Fbx4 function, and suggest that the attenuated cyclin D1 (zeige CCND1 ELISA Kits) degradation by these novel Fbx4 isoforms provides a new insight for aberrant cyclin D1 (zeige CCND1 ELISA Kits) expression in human cancers.

  2. The FBXO4 I377M mutant exhibits impaired cyclin D1 recruitment and ubiquitylation.

  3. 14-3-3varepsilon binds to Ser12-phosphorylated Fbx4 to mediate dimerization and function.

  4. Biochemical studies indicate that both the N-terminal domain and a loop connecting the linker and C-terminal domain of Fbx4 are critical for the dimerization and activation of the protein.

  5. results reveal an atypical small GTPase (zeige RACGAP1 ELISA Kits) domain within Fbx4 as a substrate-binding motif for SCF (zeige KITLG ELISA Kits)(Fbx4) and uncover a mechanism for selective ubiquitination and degradation of TRF1 (zeige TERF1 ELISA Kits) in telomere homeostasis control

  6. Fbx4 is a central regulator of Pin2/TRF1 (zeige TERF1 ELISA Kits) protein abundance and alterations in the stability of Pin2/TRF1 (zeige TERF1 ELISA Kits) can have a dramatic impact on telomere length

  7. SCF (zeige KITLG ELISA Kits)(FBX4-alphaB crystallin (zeige CRYAB ELISA Kits)) is an E3 ubiquitin ligase that promotes ubiquitin-dependent degradation of Thr286-phosphorylated cyclin D1 (zeige CCND1 ELISA Kits).

  8. Mutations in Fbx4 inhibit dimerization of the SCF (zeige KITLG ELISA Kits)(Fbx4) ligase and contribute to cyclin D1 (zeige CCND1 ELISA Kits) overexpression in human cancer.

Mouse (Murine) F-Box Protein 4 (FBXO4) Interaktionspartner

  1. Collectively, our data support a role for FBXO4 as a suppressor of esophageal tumorigenesis

  2. This study demonstrates that Fbxo4 deficiency induces Braf-driven melanoma and that this phenotype depends on cyclin D1 accumulation in mice, underscoring the importance of this ubiquitin ligase in tumor suppression.

  3. Fbx4 expression is essential for cell homeostasis in somatic cells. Fbx4 ablation predisposes mice to multiple tumor phenotypes, with concomitant cyclin D1 (zeige CCND1 ELISA Kits) deregulation and nuclear accumulation

  4. SCF (zeige KITLG ELISA Kits)(FBX4-alphaB crystallin (zeige CRYAB ELISA Kits)) is an E3 ubiquitin ligase that promotes ubiquitin-dependent degradation of Thr286-phosphorylated cyclin D1 (zeige CCND1 ELISA Kits).

  5. Lysine 269 is essential for cyclin D1 (zeige CCND1 ELISA Kits) ubiquitylation by the SCF (zeige KITLG ELISA Kits)(Fbx4/alphaB-crystallin (zeige CRYAB ELISA Kits)) ligase.

F-Box Protein 4 (FBXO4) Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants.

Genbezeichner und Symbole assoziert mit F-Box Protein 4 (FBXO4) ELISA Kits

  • F-box protein 4 (FBXO4) Antikörper
  • F-box protein 4 (Fbxo4) Antikörper
  • F-box protein 4 (fbxo4) Antikörper
  • F-box protein 4 L homeolog (fbxo4.L) Antikörper
  • 1700096C12Rik Antikörper
  • AI851261 Antikörper
  • AW494535 Antikörper
  • fbx4 Antikörper
  • FBXO4 Antikörper
  • si:dkey-46a10.2 Antikörper

Bezeichner auf Proteinebene für F-Box Protein 4 (FBXO4) ELISA Kits

F-box only protein 4 , F-box protein Fbx4 , F-box protein 4 , F-box only protein 4-like

GENE ID SPEZIES
26272 Homo sapiens
106052 Mus musculus
310363 Rattus norvegicus
431586 Gallus gallus
489220 Canis lupus familiaris
534852 Bos taurus
548694 Xenopus (Silurana) tropicalis
697007 Macaca mulatta
737372 Pan troglodytes
100158284 Xenopus laevis
100406305 Callithrix jacchus
100600195 Nomascus leucogenys
100194812 Salmo salar
101116349 Ovis aries
100735926 Cavia porcellus
100319387 Danio rerio
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