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The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. Zusätzlich bieten wir Ihnen Exportin 7 Antikörper (39) und und viele weitere Produktgruppen zu diesem Protein an.
Knockdown of exportins 4, 5, and 7 altered thyroid hormone receptor (zeige THRA ELISA Kits) shuttling dynamics, and when exportins 5 and 7 were overexpressed, TR distribution shifted toward the cytosol.
Human oligodendrogliomas cells stably expressing mutant XPO7 showed altered cell proliferation.
RAN nucleo-cytoplasmic transport and mitotic spindle assembly partners XPO7 and TPX2 (zeige TPX2 ELISA Kits) have roles in serous epithelial ovarian cancer
Knockdown of XPO7 reduced the amount of nuclear p65 (zeige GORASP1 ELISA Kits) following TNF (zeige TNF ELISA Kits) stimulation. XPO7 binding to p65 (zeige GORASP1 ELISA Kits) is NLS (zeige ALDH1A2 ELISA Kits) independent
These biochemical and functional data reveal RANBP16 and RANBP17 (zeige RANBP17 ELISA Kits) as novel regulators of E2A (zeige TCF3 ELISA Kits) protein action, and demonstrate specific interaction of E12 (zeige ELSPBP1 ELISA Kits) with RANBP17 (zeige RANBP17 ELISA Kits).
Exportin 7-dependent nuclear export signals differ fundamentally from the leucine-rich, CRM1 (zeige XPO1 ELISA Kits)-dependent ones
STRADalpha facilitates nuclear export of LKB1 (zeige STK11 ELISA Kits) by serving as an adaptor between LKB1 (zeige STK11 ELISA Kits) and exportins CRM1 (zeige XPO1 ELISA Kits) and exportin7.
Knockdown of Xpo7 in primary fetal liver erythroblasts resulted in severe inhibition of chromatin condensation and enucleation but otherwise had little effect on erythroid differentiation, including hemoglobin accumulation.
This study demonstrateg that exportin-7 responds to ischemia in astrocytes.
The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex\; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-16 is a member of the importin-beta superfamily of nuclear transport receptors.
, exportin 7
, RAN binding protein 16
, ran-binding protein 16