anti-Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2) Antikörper

Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. Zusätzlich bieten wir Ihnen EIF4G2 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
EIF4G2 1982 P78344
EIF4G2 13690 Q62448
EIF4G2 361628  
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Top anti-EIF4G2 Antikörper auf antikoerper-online.de

Showing 10 out of 118 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-EIF4G2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>721_B cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-EIF4G2 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>HepG2 cell lysate <b>Sample Type: </b>1. IAH30 cells (0.5x10<sup>6 </sup>cells loaded)<br>2. DF-1 cells (0.5x10<sup>6 </sup>cells loaded)<br><b>Primary Dilution:</b> 1:1000 <br><b>Secondary Antibody</b>: Goat anti-rabbit IgG (whole molecule) peroxidase <br><b>Secondary Dilution:</b>1:10,000 <br><b>Image Submitted By:</b> Yongxiu Yao<br>Institute for Animal Health <b><br></b> 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Maus Unkonjugiert FACS, WB Flow Cytometry: DAP5 Antibody (39C534.1) [ABIN2659439] - Intracellular flow cytometric staining of 1 x 10^6 CHO (A) and HEK-293 (B) cells using antibody (dark blue). Isotype control shown in orange. An antibody concentration of 1 ug/1x10^6 cells was used. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$415.44
Details
Rind (Kuh) Kaninchen Unkonjugiert IC, IF, IHC, WB Immunofluorescent analysis of EIF4G2 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of EIF4G2 staining in human liver cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert WB 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Maus Unkonjugiert WB EIF4G2 monoclonal antibody (M01), clone 3B5. Western Blot analysis of EIF4G2 expression in PC-12. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$450.00
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from A549 cells, using EIF4G2 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded human skeletal muscle , using DAP5, antibody(10 μg/ml). WB Image Sample(30 μg of whole cell lysate) A:A431, 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Human Kaninchen Unkonjugiert IHC (p), WB IHC-P Image DAP5 antibody [C2C3], C-term detects DAP5 protein at cytosol on mouse kidney by immunohistochemical analysis. Sample: Paraffin-embedded mouse kidney. DAP5 antibody [C2C3], C-term , dilution: 1:500. WB Image Sample (30 ug of whole cell lysate) A: Hela B: Hep G2 , 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Human Kaninchen Unkonjugiert ELISA, IF, IHC, WB Western Blot (WB) analysis of specific cells using DAP-5 Polyclonal Antibody. 100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details

EIF4G2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

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Am meisten referenzierte anti-EIF4G2 Antikörper

  1. Human Polyclonal EIF4G2 Primary Antibody für WB - ABIN1944751 : Imataka, Olsen, Sonenberg: A new translational regulator with homology to eukaryotic translation initiation factor 4G. in The EMBO journal 1997 (PubMed)
    Show all 3 Pubmed References

  2. Human Monoclonal EIF4G2 Primary Antibody für FACS, WB - ABIN265943 : Levy-Strumpf, Deiss, Berissi, Kimchi: DAP-5, a novel homolog of eukaryotic translation initiation factor 4G isolated as a putative modulator of gamma interferon-induced programmed cell death. in Molecular and cellular biology 1997 (PubMed)
    Show all 6 Pubmed References

  3. Human Monoclonal EIF4G2 Primary Antibody für IHC (p), ELISA - ABIN560721 : Katsogiannou, Andrieu, Baylot, Baudot, Dusetti, Gayet, Finetti, Garrido, Birnbaum, Bertucci, Brun, Rocchi: The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets. in Molecular & cellular proteomics : MCP 2014 (PubMed)

Weitere Antikörper gegen EIF4G2 Interaktionspartner

Zebrafish Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2) Interaktionspartner

Xenopus laevis Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2) Interaktionspartner

Human Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2) Interaktionspartner

  1. DAP5 knockdown from human ESCs (zeige NR2E3 Antikörper) (hESCs) resulted in persistence of pluripotent gene expression, delayed induction of differentiation-associated genes in different cell lineages, and defective embryoid body formation

  2. Data show that microRNA miR (zeige MLXIP Antikörper)-379 potentiated lung cancer (LCa (zeige CLTA Antikörper)) chemosensitivity via modulation of cisplatin (CDDP)-induced apoptosis by directly targeting the eukaryotic translation initiation factor 4 gamma 2 (EIF4G2) 3' UTR (zeige UTS2R Antikörper).

  3. These results indicate that miR (zeige MLXIP Antikörper)-139 is capable of inhibiting chondrocyte proliferation and migration, thus being a possible therapeutic target for OA. The mechanism of miR (zeige MLXIP Antikörper)-139 in chondrocytes may be related to its regulation on EIF4G2 and IGF1R (zeige IGF1R Antikörper).

  4. The Coxsackievirus B3 protease 2A-mediated cleavage of DAP5 results in the production of two truncates that exert differential effects on protein translation of the IRES-containing genes, leading to enhanced host cell death.

  5. Knockdown of EIF4G2 recapitulated the effects of mir (zeige MLXIP Antikörper)-139, whereas restoring EIF4G2 expression rescued the mir (zeige MLXIP Antikörper)-139 phenotype. elevated miR (zeige MLXIP Antikörper)-139-5p expression is associated with a favorable outcome in acute myeloid leukemia (zeige BCL11A Antikörper).

  6. findings provide the first mechanistic insights into the function of DAP5 as a selective regulator of cap-independent translation

  7. Our results provide evidence that the tumor suppressor effect of miR (zeige MLXIP Antikörper)-520c-3p is mediated through repression of translation while inducing senescence and that eIF4GII (zeige EIF4G3 Antikörper) is a key effector of this anti-tumor activity.

  8. DAP5, a translation initiation factor shown to positively regulate the translation of various internal ribosome entry sites containing mRNAs, promotes internal ribosome entry site-driven translation of p53 (zeige TP53 Antikörper) mRNA.

  9. DAP5/p97 and DAP5/p86 enhanced the translation of the anti-apoptotic protein Bcl-2 (zeige BCL2 Antikörper) and inhibited cisplatin-induced apoptosis

  10. Multiple isoforms of eIF4GII (zeige EIF4G3 Antikörper) arise from multiple promoters & alternative splicing events. A non-canonical CUG initiation codon extends the eIF4GII (zeige EIF4G3 Antikörper) N-terminus. The eIF4GII (zeige EIF4G3 Antikörper) N-terminus plays an alternative role in initiation factor assembly.

Mouse (Murine) Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2) Interaktionspartner

  1. analysis of the tandem MA-3 (zeige PDCD6 Antikörper) region of Pdcd4 (zeige PDCD4 Antikörper) protein and characterization of its interactions with eIF4A (zeige EIF4A1 Antikörper) and eIF4G (zeige EIF4G1 Antikörper)

EIF4G2 Antigen-Profil

Protein Überblick

Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3\; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.

Genbezeichner und Symbole assoziert mit EIF4G2

  • eukaryotic translation initiation factor 4, gamma 2b (eif4g2b) Antikörper
  • eukaryotic translation initiation factor 4 gamma 2 (EIF4G2) Antikörper
  • eIF4G-related protein NAT1 (nat1) Antikörper
  • eukaryotic translation initiation factor 4 gamma, 2 (EIF4G2) Antikörper
  • eukaryotic translation initiation factor 4, gamma 2 (Eif4g2) Antikörper
  • AA589388 Antikörper
  • AAG1 Antikörper
  • DAP-5 Antikörper
  • DAP5 Antikörper
  • E130105L11Rik Antikörper
  • EIF4G2 Antikörper
  • hm:zeh1307 Antikörper
  • Nat1 Antikörper
  • NAT1B Antikörper
  • Natm1 Antikörper
  • P97 Antikörper
  • wu:fa14h01 Antikörper
  • wu:fb44h01 Antikörper
  • wu:fb59c06 Antikörper
  • wu:fc21b05 Antikörper

Bezeichner auf Proteinebene für EIF4G2

eukaryotic translation initiation factor 4 gamma, 2 , fb44h01 , eukaryotic translation initiation factor 4 gamma 2 , Eukaryotic translation initiation factor 4 gamma 2 , DAP-5 , aging-associated protein 1 , death-associated protein 5 , eIF-4-gamma 2 , eIF-4G 2 , eIF4G 2 , eukaryotic translation initiation factor 4G-like 1 , eIF4G-related protein NAT1 , p97 , novel APOBEC-1 target 1 , translation repressor NAT1 , translation repressor Nat1

GENE ID SPEZIES
334618 Danio rerio
466443 Pan troglodytes
705510 Macaca mulatta
100173304 Pongo abelii
496405 Xenopus laevis
1982 Homo sapiens
395905 Gallus gallus
476854 Canis lupus familiaris
286870 Bos taurus
100009236 Oryctolagus cuniculus
13690 Mus musculus
361628 Rattus norvegicus
Ausgewählte Anbieter für anti-EIF4G2 (EIF4G2) Antikörper
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