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EPCAM encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. Zusätzlich bieten wir Ihnen EPCAM Antikörper (1143) und EPCAM Proteine (47) und viele weitere Produktgruppen zu diesem Protein an.
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Human EPCAM ELISA Kit für Sandwich ELISA - ABIN414691
Bravo, Ortega, Messina, Sanz, Fernández-Baldo, Raba: Integrated bio-affinity nano-platform into a microfluidic immunosensor based on monoclonal bispecific trifunctional antibodies for the electrochemical determination of epithelial cancer biomarker. in Clinica chimica acta; international journal of clinical chemistry 2016
Show all 2 Pubmed References
Our study provided clinical evidence for EpCAM intracellular domain as a predictor of cancer development in patients with oral dysplasia and recurrence in oral squamous cell carcinoma patients
Elevated epithelial cell adhesion molecule EpCAM (mRNA+) CTC and Treg/CD4 (zeige CD4 ELISA Kits)(+) levels were associated with early recurrence of hepatocellular carcinoma (HCC (zeige FAM126A ELISA Kits)), indicative of poor clinical outcome.
Observations provide important insights into the regulation of EpCAM expression during EMT (zeige ITK ELISA Kits), demonstrate an unexpected role for EpCAM in the regulation of ERK (zeige EPHB2 ELISA Kits) and define a novel double-negative feedback loop between EpCAM and ERK (zeige EPHB2 ELISA Kits) that contributes to the regulation of EMT (zeige ITK ELISA Kits).
This study shows the potential of an EpCAM specific NIR-fluorescent agent in combination with a clinically validated intraoperative imaging system to visualize various tumours during surgery.
The studies identified the characteristics and function of EpCAM glycosylation sites on breast cancer cell adhesion.
These results identify EpCAM as a substrate of matriptase (zeige ST14 ELISA Kits) and link HAI-2 (zeige SPINT2 ELISA Kits), matriptase (zeige ST14 ELISA Kits), EpCAM, and claudin-7 (zeige CLDN7 ELISA Kits) in a functionally important pathway that causes disease when it is dysregulated.
The EpCAM aptamer conjugated NCS showed specificity to EpCAM-positive cells.
Pseudomyxoma peritonei ubiquitously express CEA (zeige CEACAM5 ELISA Kits) and EpCAM.
relationship between EpCAM-regulated transcription and altered biophysical properties of cells that promoteepithelial-mesenchymal transition (EMT (zeige ITK ELISA Kits)) in advanced endometrial cancer.
used a next generation sequencing (NGS) approach. NY-SAR-35 expression induced growth, proliferation, metastasis, and stemness genes, as indicated by the up-regulations of CXCR4 (zeige CXCR4 ELISA Kits), EpCAM, CD133, and CD44 (zeige CD44 ELISA Kits), at the mRNA and protein levels
Ep-CAM may act as a physical homophilic interaction molecule between IELs and IECs at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection [Ep-CAM]
Gene ontology analysis revealed that EpCAM controls various developmental programs, including uretric bud development, morphogenesis of branching epithelium, regulation of cell differentiation and cilium morphogenesis.
EpCAM acts as a partner of E-cadherin (zeige CDH1 ELISA Kits) to control adhesiveness and integrity as well as plasticity and morphogenesis within simple epithelia
identification of EpCAM in a gain-of-function screen for inducers of abnormal tissue mixing during gastrulation
activation of hepatic H19RNA promoted cholestatic liver fibrosis through the ZEB1 (zeige ZEB1 ELISA Kits)/EpCAM signaling pathway
EpCAM appears to differentially regulate Langerhans cell mobility/migration in the setting of limited inflammation as compared with the intense inflammation triggered by contact sensitizers
Knock-down EpCAM cell model of congenital tufting enteropathy was developed. In vivo inducible mouse model was developed resulting in mutant EpCAM protein.
in addition to converting to cholangiocyte-like cells, Sox9 (zeige SOX9 ELISA Kits)(+)EpCAM(-) cells provide luminal space near expanded ductular structures to prevent deterioration of the injuries and potentially supply new hepatocytes to repair damaged tissues
EpCAM is a highly conserved protein present in fishes, amphibians, reptiles, birds, marsupials, and placental mammals, and is subject to shedding, gamma-secretase-dependent regulated intramembrane proteolysis, and proteasome-mediated degradation.
Suggest pivotal role of EpCAM in intestinal epithelial structure and integrity, with mutations resulting in congenital tufting enteropathy.
mTrop1/Epcam knockout mice develop congenital tufting enteropathy through dysregulation of intestinal E-cadherin (zeige CDH1 ELISA Kits)/beta-catenin (zeige CTNNB1 ELISA Kits).
EpCAM contributes to formation of intestinal barrier by recruiting claudins to cell-cell junctions.
These results conclusively link EpCAM expression to Langerhan cell (LC) motility/migration and LC migration to immune regulation.
This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.
, cell surface glycoprotein Trop-1
, epithelial glycoprotein 314
, human epithelial glycoprotein-2
, major gastrointestinal tumor-associated protein GA733-2
, membrane component, chromosome 4, surface marker (35kD glycoprotein)
, tumor-associated calcium signal transducer 1
, epithelial glycoprotein
, pan-epithelial glycoprotein
, tumor-associated calcium signal transducer
, epithelial cell adhesion molecule
, Trop-1 protein
, lymphocyte antigen 74
, panepithelial glycoprotein 314
, protein 289A