anti-Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) Antikörper

Aminopeptidases hydrolyze N-terminal amino acids of proteins or peptide substrates. Zusätzlich bieten wir Ihnen Endoplasmic Reticulum Aminopeptidase 2 Kits (7) und Endoplasmic Reticulum Aminopeptidase 2 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ERAP2 64167 Q6P179
ERAP2    
ERAP2 513572 A6QPT7
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Top anti-Endoplasmic Reticulum Aminopeptidase 2 Antikörper auf antikoerper-online.de

Showing 10 out of 28 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Ziege Unkonjugiert ELISA, WB 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$485.88
Details
Rind (Kuh) Ziege Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$455.40
Details
Human Ziege Unkonjugiert ELISA, WB ABIN302141 (0.5µg/ml) staining of Spleen lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Ziege Unkonjugiert ELISA, WB 0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$481.25
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of extracts of various cells, using ERAP2 antibody. 100 μL Anmelden zum Anzeigen 16 Days
$334.02
Details
Rind (Kuh) Ziege Unkonjugiert ELISA, WB ABIN2562453 (0.5µg/ml) staining of Spleen lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μL Anmelden zum Anzeigen 16 Days
$444.57
Details
Human Kaninchen Unkonjugiert IF, IHC (p), ELISA, WB   50 μg Anmelden zum Anzeigen 12 bis 14 Tage
$593.40
Details
Human Ziege FITC ELISA, WB   100 μL Anmelden zum Anzeigen 16 Days
$760.57
Details
Human Ziege APC ELISA, WB   100 μL Anmelden zum Anzeigen 16 Days
$760.57
Details
Human Ziege Biotin ELISA, WB   100 μL Anmelden zum Anzeigen 16 Days
$760.57
Details

ERAP2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human
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, , , , ,
Mouse (Murine)


Cow (Bovine)


Am meisten referenzierte anti-Endoplasmic Reticulum Aminopeptidase 2 Antikörper

  1. Human Polyclonal ERAP2 Primary Antibody für ELISA, WB - ABIN451676 : Saveanu, Carroll, Lindo, Del Val, Lopez, Lepelletier, Greer, Schomburg, Fruci, Niedermann, van Endert: Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum. in Nature immunology 2005 (PubMed)

Weitere Antikörper gegen Endoplasmic Reticulum Aminopeptidase 2 Interaktionspartner

Human Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) Interaktionspartner

  1. ERAP1 and ERAP2 have significant and distinct effects on the HLA-B*27 peptidome, suggesting that both enzymes largely act as separate entities in vivo. This may explain their different patterns of association with AS.

  2. This review focuses on the ambivalent role of HLA-B27 in autoimmunity and viral protection correlating its functions to the quantitative and qualitative effects of ERAP1 (zeige ERAP1 Antikörper) and ERAP2 polymorphisms on their enzymatic activity.

  3. ERAP2 deficiency causes increased MHC class I free heavy chain expression and up-regulation of the unfolded protein response pathway in anklyosing spondylitis.

  4. ERAP-2 significantly influences the B*27:05-bound peptidome by destroying some ligands and decreasing the abundance of many more ligands with N-terminal basic residues, while increasing the abundance of nonamers. The former effects are best explained by direct ERAP-2 trimming. The effects on peptide length might be attributed to ERAP-2-induced activation of ERAP-1 (zeige ERAP1 Antikörper) trimming. These data support the notion of a peptide-media

  5. study reveals fine-mapped AID risk variants that act as eQTLs with ERAP2 in thymus

  6. there is a significant association of ERAP2 with psoriatic arthritis and HLA-B27 negative psoriatic arthritis, while ERAP1 association is restricted only to HLA-B27 positive disease

  7. Increased expression of ERAP2 in GC-responders before therapy warrants further investigation into their role as potential predictors for the response to GC, and in the inflammatory process of rheumatoid arthritis.

  8. ERAP2 is associated with ankylosing spondylitis in HLA-B27 positive and HLA-B27 negative patients.

  9. ERAP2 might be associated with CLNM in PTMC.

  10. ERAP2 variation does not have a significant effect on PBMC intracellular and cell surface HLA-class I (zeige MICA Antikörper) expression and heavy chain formation, markers of ER stress or inflammatory cytokine production.

Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) Antigen-Profil

Protein Überblick

Aminopeptidases hydrolyze N-terminal amino acids of proteins or peptide substrates. Major histocompatibility complex (MHC) class I molecules rely on aminopeptidases such as ERAP1 (MIM 606832) and LRAP to trim precursors to antigenic peptides in the endoplasmic reticulum (ER) following cleavage in the cytoplasm by tripeptidyl peptidase II (TPP2\; MIM 190470) (Tanioka et al., 2003

Genbezeichner und Symbole assoziert mit ERAP2

  • endoplasmic reticulum aminopeptidase 2 (ERAP2) Antikörper
  • endoplasmic reticulum aminopeptidase 2 (erap2) Antikörper
  • ERAP2 Antikörper
  • L-RAP Antikörper
  • LRAP Antikörper
  • zgc:172163 Antikörper

Bezeichner auf Proteinebene für ERAP2

leukocyte-derived arginine aminopeptidase , endoplasmic reticulum aminopeptidase 2 , endoplasmic reticulum aminopeptidase 2-like

GENE ID SPEZIES
64167 Homo sapiens
461959 Pan troglodytes
513572 Bos taurus
700118 Macaca mulatta
100171433 Pongo abelii
100402550 Callithrix jacchus
100856345 Canis lupus familiaris
100073223 Equus caballus
100525036 Sus scrofa
100144556 Danio rerio
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