Echinoderm Microtubule Associated Protein Like 4 Proteine (EML4)

May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity). Zusätzlich bieten wir Ihnen EML4 Antikörper (34) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Ratte EML4 EML4 313861  
EML4 27436 Q9HC35
EML4 78798 Q3UMY5
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Showing 4 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 66 Days
10.536,00 €
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 66 Days
10.536,00 €
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 16 Days
748,00 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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EML4 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Weitere Proteine zu Echinoderm Microtubule Associated Protein Like 4 (EML4) Interaktionspartnern

Human Echinoderm Microtubule Associated Protein Like 4 (EML4) Interaktionspartner

  1. Knockdown of SMYD2 as well as treatment with a SMYD2 inhibitor in two NSCLC cell lines with an EML4-ALK gene significantly attenuated the phosphorylation levels of the EML4-ALK protein.

  2. The EML4-ALK-mediated upregulation of HIF1alpha, HK2 and glycolytic metabolism was also highly active in vivo as demonstrated by fluorodeoxyglucose-positron emission tomography imaging of xenografts grown from EML4-ALK-positive NSCLC cells.

  3. We assessed the prevalence of EML4-ALK rearrangement gene measured by immunohistochemistry in an unselected population-based consecutive cohort of patients with adenocarcinoma of the lung (ACL (zeige ACLY Proteine)), and the correlation with smoking history, thyroid transcription factor 1 (TTF1 (zeige NKX2-1 Proteine)), gender and age

  4. Our findings show that group EML4-ALK variants 3a/b in non-small cell lung cancer may be a major source of ALK inhibitor resistance in the clinic.

  5. EML4-ALK rearrangement detection in malignant pleural effusions is a complementary method for EML4-ALK detection. VETANA and qRT-PCR are more appropriate for MPE detection. EML4-ALK rearrangement in pleural effusions has a predictive value for treatment.

  6. EML4-ALK-positive lung cancer is often highly progressive.

  7. case report in which the EML4-ALK fusion gene was identified as a second primary lung cancer after surgically resecting EGFR (zeige EGFR Proteine) mutation-positive adenocarcinoma

  8. 79 (69%) were negative for echinoderm microtubule-associated protein like 4 (EML4)-ALK translocation, nine (8%) were positive and 27 (23%) were unevaluable.

  9. Data suggest that platelets are a valuable source for the non-invasive detection of echinoderm microtubule associated protein like 4-anaplastic lymphoma kinase (EML4-ALK) rearrangements and for predicting and monitoring outcome to crizotinib.

  10. Data show that inhibition of echinoderm microtubule-associated protein-like 4 (EML4)-anaplastic lymphoma kinase (ALK)-mediated stem-like properties enhances the anti-tumor effect.

EML4 Protein Überblick

Protein Überblick

May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity).

Genbezeichner und Symbole assoziert mit EML4

  • echinoderm microtubule associated protein like 4 (Eml4)
  • echinoderm microtubule associated protein like 4 (EML4)
  • echinoderm microtubule associated protein like 4 (eml4)
  • 4930443C24Rik Protein
  • AI644019 Protein
  • C2orf2 Protein
  • ELP120 Protein
  • EMAP-4 Protein
  • EMAPL4 Protein
  • EML4 Protein
  • MGC89332 Protein
  • ROPP120 Protein

Bezeichner auf Proteinebene für EML4

echinoderm microtubule-associated protein-like 4 , echinoderm microtubule associated protein like 4 , echinoderm microtubule-associated protein-like 4-like , restrictedly overexpressed proliferation-associated protein , ropp 120 , EMAP-4

GENE ID SPEZIES
313861 Rattus norvegicus
483048 Canis lupus familiaris
540187 Bos taurus
100515021 Sus scrofa
448764 Xenopus (Silurana) tropicalis
459180 Pan troglodytes
715091 Macaca mulatta
771345 Gallus gallus
100053784 Equus caballus
100453034 Pongo abelii
27436 Homo sapiens
78798 Mus musculus
735022 Xenopus laevis
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