anti-Dynamin 1-Like (DNM1L) Antikörper

The protein encoded by DNM1L is a member of the dynamin superfamily of GTPases. Zusätzlich bieten wir Ihnen Dynamin 1-Like Proteine (7) und Dynamin 1-Like Kits (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
DNM1L 10059 O00429
DNM1L 74006 Q8K1M6
DNM1L 114114 O35303
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Top anti-Dynamin 1-Like Antikörper auf antikoerper-online.de

Showing 10 out of 127 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-DNM1L Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>Hela cell lysate <b>Sample Type</b>: 2. mouse brain extracts (80ug)<br> <b>Primary Antibody Dilution:</b> 2ug/ml<br> <b>Secondary Antibody</b>: IRDye 800CW goat anti-rabbit from Li-COR Bioscience<br> <b>Secondary Antibody Dilution:</b> 1: 20,000<br> <b>Image Submitted by</b>: Yuzhi Chen<br> University of Arkansas for Medical Science 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Fisch Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), IP, SimWes, WB Staining of renal tubular epithelium and visceral epithelial cells of the glomerulus using ABIN258397 at 2.5ug/ml.  Human kidney cortex, 40X magnification. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$514.63
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), IP, SimWes, WB Staining of renal tubular epithelium and visceral epithelial cells of glomeruli using ABIN258391 at 2.5ug/ml.  Human kidney cortex, 40X magnification. Staining of DRP-1 in mouse embryonic fibroblast post-nuclear extracts using ABIN258391. Image courtesy of D. Chan California Institute of Technology. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$485.88
Details
Human Maus Unkonjugiert IHC, ELISA, WB 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$430.10
Details
Hund Maus Unkonjugiert IF, WB Western blot analysis of Drp1 on a HCT-8 cell lysate (Human colorectal adenocarcinoma, ATCC CCL-244). Lane 1: 1:500, lane 2: 1:1000, lane 3: 1:2000 dilution of the mouse anti-Drp1 antibody. Immunofluorescence staining on A431 cells (Human epithelial carcinoma, ATCC CRL-1555). 150 μg Anmelden zum Anzeigen 6 bis 8 Tage
$305.54
Details
Human Maus Unkonjugiert ICC, FACS, ELISA, WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$430.10
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB 100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB Western Blot (WB) analysis of specific cells using DRP1 Polyclonal Antibody. 100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Maus Unkonjugiert IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to DNM1L on formalin-fixed paraffin-embedded human leiomyosarcoma tissue. [antibody concentration 1 ug/ml] DNM1L monoclonal antibody (M01), clone 3B5 Western Blot analysis of DNM1L expression in K-562 . 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details

DNM1L Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Dynamin 1-Like Antikörper

  1. Fish Polyclonal DNM1L Primary Antibody für ICC, IF - ABIN258397 : Manczak, Calkins, Reddy: Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage. in Human molecular genetics 2011 (PubMed)
    Show all 16 Pubmed References

  2. Human Polyclonal DNM1L Primary Antibody für ICC, IF - ABIN258391 : Cheng, Guo, Copps, Dong, Kollipara, Rodgers, Depinho, Puigserver, White: Foxo1 integrates insulin signaling with mitochondrial function in the liver. in Nature medicine 2009 (PubMed)
    Show all 14 Pubmed References

  3. Mouse (Murine) Polyclonal DNM1L Primary Antibody für IHC - ABIN966011 : Honda, Hirose: Stage-specific enhanced expression of mitochondrial fusion and fission factors during spermatogenesis in rat testis. in Biochemical and biophysical research communications 2003 (PubMed)
    Show all 5 Pubmed References

  4. Human Monoclonal DNM1L Primary Antibody für IHC (p), ELISA - ABIN564347 : Figueroa-Romero, Iñiguez-Lluhí, Stadler, Chang, Arnoult, Keller, Hong, Blackstone, Feldman: SUMOylation of the mitochondrial fission protein Drp1 occurs at multiple nonconsensus sites within the B domain and is linked to its activity cycle. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009 (PubMed)
    Show all 4 Pubmed References

  5. Human Monoclonal DNM1L Primary Antibody für IHC, ELISA - ABIN1724863 : Thomas, Jacobson: Defects in mitochondrial fission protein dynamin-related protein 1 are linked to apoptotic resistance and autophagy in a lung cancer model. in PLoS ONE 2012 (PubMed)
    Show all 2 Pubmed References

  6. Human Monoclonal DNM1L Primary Antibody für ICC, FACS - ABIN1724907 : Marsboom, Toth, Ryan, Hong, Wu, Fang, Thenappan, Piao, Zhang, Pogoriler, Chen, Morrow, Weir, Rehman, Archer: Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension. in Circulation research 2012 (PubMed)
    Show all 2 Pubmed References

  7. Dog (Canine) Monoclonal DNM1L Primary Antibody für IF, WB - ABIN968652 : Deyo, Chiao, Tainsky: drp, a novel protein expressed at high cell density but not during growth arrest. in DNA and cell biology 1998 (PubMed)

  8. Cow (Bovine) Polyclonal DNM1L Primary Antibody für IHC, WB - ABIN2784887 : Su, Chiu, Hung, Hong: Beta-nodavirus B2 protein induces hydrogen peroxide production, leading to Drp1-recruited mitochondrial fragmentation and cell death via mitochondrial targeting. in Apoptosis : an international journal on programmed cell death 2014 (PubMed)

Weitere Antikörper gegen Dynamin 1-Like Interaktionspartner

Human Dynamin 1-Like (DNM1L) Interaktionspartner

  1. The structure and function of DNM1L protein in mitochondrial fission is reviewed.

  2. Results described a recessive disease caused by DNM1L mutations, with a clinical phenotype resembling mitochondrial disorders but without any typical biochemical features. Two novel DNM1L mutations (one frame-shift mutation and one missense mutation) are identified and was found to be associated with impaired mitochondrial and peroxisomal morphology.

  3. Study describes mutations in ZNF143 (zeige ZNF143 Antikörper) causing a previously undescribed inherited disorder of vitamin B12 (zeige NDUFB3 Antikörper) (cobalamin) metabolism. These mutations cause an accumulation of transcobalamin-bound cobalamin within the cells, as well as decreased expression of MMACHC (zeige MMACHC Antikörper), a cobalamin trafficking protein.

  4. The results suggest that endoplasmic reticulum (ER) can function as a platform for Drp1 (zeige CRMP1 Antikörper) oligomerization, and that ER-associated Drp1 (zeige CRMP1 Antikörper) contributes to mitochondrial division.

  5. PRKAA (zeige PRKAA2 Antikörper) deletion promoted mitochondrial fragmentation in vascular endothelial cells by inhibiting the autophagy-dependent degradation of DNM1L.

  6. hepatic stimulator substance could regulate mitochondrial fission and hepatocyte apoptosis during liver ischemia/reperfusion injury by orchestrating the translocation and activation of Drp1 (zeige CRMP1 Antikörper)

  7. This report describes a patient with a DNM1L mutation and abnormalities in mitochondrial fission and function. The pathogenicity and the dominant nature of the novel p.G362S mutation are demonstrated by overexpression of the mutant gene.

  8. In contrast to the initial report of neonatal lethality resulting from DNM1L mutation and DRP1 (zeige CRMP1 Antikörper) dysfunction, our results show that milder DRP1 (zeige CRMP1 Antikörper) impairment is compatible with normal early development and subsequently results in a distinct set of neurological findings. In addition, we identify a common pathogenic mechanism whereby DNM1L mutations impair mitochondrial fission.

  9. These findings provide new insights into MCL-1 (zeige MCL1 Antikörper) ligands, and the interplay between DRP-1 (zeige CRMP1 Antikörper) and the anti-apoptotic BCL-2 (zeige BCL2 Antikörper) family members in the regulation of apoptosis

  10. High drp1 (zeige CRMP1 Antikörper) expression is associated with cisplatin-induced apoptosis of renal tubular epithelial cells.

Mouse (Murine) Dynamin 1-Like (DNM1L) Interaktionspartner

  1. The Drp1 (zeige CRMP1 Antikörper) might play a significant role in lamellipodia formation and cell spreading through a different mechanism from that used for regulating mitochondrial dynamics/function.

  2. The structure and function of Dnm1l protein in mitochondrial fission is reviewed.

  3. screening a panel of proteins that regulate mitochondrial morphology in bella GCs (zeige UGCG Antikörper) revealed de-regulation of phospho-Drp1 (zeige CRMP1 Antikörper)(Ser616), a key mitochondrial fission regulatory factor. Our data provide new insights into the function of Oxr1 (zeige OXR1 Antikörper), revealing that specific isoforms of this novel antioxidant protein (zeige PRDX3 Antikörper) are associated with mitochondria.

  4. PRKAA (zeige PRKAA2 Antikörper) deletion promoted mitochondrial fragmentation in vascular endothelial cells by inhibiting the autophagy-dependent degradation of DNM1L.

  5. hepatic stimulator substance could regulate mitochondrial fission and hepatocyte apoptosis during liver ischemia/reperfusion injury by orchestrating the translocation and activation of Drp1 (zeige CRMP1 Antikörper)

  6. Pharmacological inhibition of Drp1 (zeige CRMP1 Antikörper) prevents mitochondrial fission and reduces myocardial ischemia-reperfusion injury in diabetic mice.

  7. Report a novel non-canonical function of the fission protein, DRP1 (zeige CRMP1 Antikörper) in maintaining or positively stimulating mitochondrial respiration, bioenergetics and ROS (zeige ROS1 Antikörper) signalling in adult cardiomyocyte, which is likely independent of morphological changes.

  8. Deletion of Sirt5 (zeige SIRT5 Antikörper) in starved mouse embryonic fibroblasts increased levels of mitochondrial dynamics leading to mitochondrial accumulation of the pro-fission Drp1 (zeige CRMP1 Antikörper) and to mitochondrial fragmentation.

  9. Podocyte apoptosis induced by hyperglycemia can be reversed by polydatin through suppressing Drp1 (zeige CRMP1 Antikörper) expression.

  10. Heat acclimation and heat shock cause changes in mitochondrial morphology of muscle cells by acting on Drp1 (zeige CRMP1 Antikörper), which results in favoring mitochondrial fusion and fission, respectively.

Rabbit Dynamin 1-Like (DNM1L) Interaktionspartner

  1. The authors conclude that clathrin-independent compensatory endocytosis in umbrella cells is integrin regulated and occurs by a RhoA (zeige RHOA Antikörper)- and dynamin (zeige DNM1 Antikörper)-dependent pathway.

Fruit Fly (Drosophila melanogaster) Dynamin 1-Like (DNM1L) Interaktionspartner

  1. Data show that short-term induction of Drp1 (zeige DAPK2 Antikörper), in midlife, is sufficient to improve organismal health and prolong lifespan.

  2. Study showed that exogenous expression of Drp1 (zeige DAPK2 Antikörper) could promote crawling ability, reduced the level of ATP in Drosophila brain and suppressed neuronal degeneration, suggesting that Drp1 (zeige DAPK2 Antikörper) is involved in the pathogenesis of Alzheimer disease.

  3. Results show that centronuclear myopathy associated Dyn2 (zeige DNM2 Antikörper) mutants are gain-of-function mutations, and their primary effect in muscle is T-tubule disorganization, which explains the susceptibility of muscle to Dyn2 (zeige DNM2 Antikörper) hyperactivity.

  4. Debcl modulates Drp1 (zeige DAPK2 Antikörper) mitochondrial localization during apoptosis.

  5. Thus, DRP1 (zeige DAPK2 Antikörper)-dependent mitochondrial fission activity is a novel regulator of the onset of follicle cell differentiation during Drosophila

  6. Alterations in both mitochondrial morphology and ATP production caused by either parkin (zeige PARK2 Antikörper) or PINK1 (zeige PINK1 Antikörper) loss of function could be rescued by the mitochondrial fusion proteins Mfn2 (zeige MFN2 Antikörper) and OPA1 (zeige OPA1 Antikörper) or by a dominant negative mutant of the fission protein Drp1.

Dynamin 1-Like (DNM1L) Antigen-Profil

Protein Überblick

The protein encoded by this gene is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated.

Genbezeichner und Symbole assoziert mit anti-Dynamin 1-Like (DNM1L) Antikörper

  • dynamin 1 like (DNM1L) Antikörper
  • dynamin 1-like (Dnm1l) Antikörper
  • dynamin 1-like L homeolog (dnm1l.L) Antikörper
  • dynamin 1-like (dnm1l) Antikörper
  • dynamin-1-like (LOC100369408) Antikörper
  • dynamin 1 like (dnm1l) Antikörper
  • dynamin-1-like protein (LOC411472) Antikörper
  • dynamin-like protein (dyn1) Antikörper
  • dynamin-like protein (cgd1_580) Antikörper
  • dynamin-like protein (EHI_052740) Antikörper
  • dynamin-like protein (PVX_092875) Antikörper
  • dynamin-like protein (BBOV_II002980) Antikörper
  • dynamin 1 like (Dnm1l) Antikörper
  • Dynamin related protein 1 (Drp1) Antikörper
  • 18.m06247 Antikörper
  • 6330417M19Rik Antikörper
  • AI450666 Antikörper
  • CG3210 Antikörper
  • Dlp1 Antikörper
  • Dmel\CG3210 Antikörper
  • Dnm1/Drp1 Antikörper
  • DNM1L Antikörper
  • Dnml1 Antikörper
  • Dnmlp1 Antikörper
  • Drp Antikörper
  • drp-1 Antikörper
  • drp1 Antikörper
  • DVLP Antikörper
  • DYMPLE Antikörper
  • EMPF Antikörper
  • frat Antikörper
  • HDYNIV Antikörper
  • l(2)22Fc Antikörper
  • l(2)22Fd Antikörper
  • l(2)ND2 Antikörper
  • l(2)ND3 Antikörper
  • MGC53850 Antikörper
  • python Antikörper
  • zgc:66163 Antikörper

Bezeichner auf Proteinebene für anti-Dynamin 1-Like (DNM1L) Antikörper

Dnm1p/Vps1p-like protein , dynamin family member proline-rich carboxyl-terminal domain less , dynamin-1-like protein , dynamin-like protein 4 , dynamin-like protein IV , dynamin-related protein 1 , dymple , C-terminal region , N-terminal region , dynamin-like protein 1 , dynamin 1-like , Dynamin-1-like protein , dynamin-1-like protein-like , dynamin related protein 1 , dynamin-like protein , CG3210 gene product from transcript CG3210-RB , CG3210-PA , CG3210-PB , Drp1-PA , Drp1-PB , dynamin related protein-1 , dynamin-2 , dynamin-related protein , dynaminrelated protein 1 , fratboy , lethal(2)22Fc , lethal(2)22Fd , near dpp complementation group 2 , near dpp complementation group 3 , noodle

GENE ID SPEZIES
10059 Homo sapiens
74006 Mus musculus
114114 Rattus norvegicus
379875 Xenopus laevis
393896 Danio rerio
418132 Gallus gallus
465266 Pan troglodytes
477649 Canis lupus familiaris
540892 Bos taurus
695388 Macaca mulatta
100229161 Taeniopygia guttata
100338814 Oryctolagus cuniculus
100369408 Saccoglossus kowalevskii
100380278 Salmo salar
100474116 Ailuropoda melanoleuca
100560647 Anolis carolinensis
411472 Apis mellifera
811008 Plasmodium falciparum 3D7
3371500 Cryptosporidium parvum Iowa II
3405942 Entamoeba histolytica HM-1:IMSS
5474863 Plasmodium vivax Sal-1
5478050 Babesia bovis T2Bo
100728964 Cavia porcellus
33445 Drosophila melanogaster
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