Dual Specificity Phosphatase 10 (DUSP10) ELISA Kits

Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. Zusätzlich bieten wir Ihnen Dual Specificity Phosphatase 10 Antikörper (99) und Dual Specificity Phosphatase 10 Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Human DUSP10 DUSP10 11221 Q9Y6W6
Anti-Maus DUSP10 DUSP10 63953 Q9ESS0
Anti-Ratte DUSP10 DUSP10 63995  
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Weitere ELISA Kits für Dual Specificity Phosphatase 10 Interaktionspartner

Human Dual Specificity Phosphatase 10 (DUSP10) Interaktionspartner

  1. High DUSP10 expression is associated with Metastasis of Hepatocellular Carcinoma.

  2. This study demonstrates that AGR2 (zeige AGR2 ELISA Kits), which is overexpressed in a variety of human cancers and provides a poor prognosis, up-regulates DUSP10 which subsequently inhibits p38 MAPK (zeige MAPK14 ELISA Kits) and prevents p53 (zeige TP53 ELISA Kits) activation by phosphorylation.

  3. Increased Dusp10 expression is associated with better survival rate in colorectal cancer patients.

  4. Data suggest that vitamin D receptor target genes (DUSP10; THBD, thrombomodulin; NRIP1, nuclear receptor interacting protein 1; TRAK1, trafficking protein kinesin binding 1) can be used as markers for individual's response to vitamin D3 supplements.

  5. Certain mutations in DUSP10 correlate with the incidence of colorectal cancer(CRC). Thus, the function of the DUSP10 gene product may contribute toward CRC in the Han Chinese population.

  6. Single nucleotide polymorphism in DUSP10 gene is associated with celiac disease.

  7. Depletion of miR (zeige MLXIP ELISA Kits)-181 family members by miRNA inhibitors enhanced the expression of MKP-5 and suppressed the phosphorylation of p38 MAPK (zeige MAPK14 ELISA Kits) after exposure to PAHs, which promotes cancer cell migration.

  8. Data indicate that the activities of phosphoprotein phosphatases MKP5 and MKP7 (zeige DUSP16 ELISA Kits) were determined in the system.

  9. MKP-5 interacts with ERK (zeige EPHB2 ELISA Kits), retains it in the cytoplasm, suppresses its activation and downregulates ERK (zeige EPHB2 ELISA Kits)-dependent transcription.

  10. A distinct interaction mode revealed by the crystal structure of the kinase p38alpha (zeige MAPK14 ELISA Kits) with the MAPK (zeige MAPK1 ELISA Kits) binding domain of the phosphatase MKP5.

Mouse (Murine) Dual Specificity Phosphatase 10 (DUSP10) Interaktionspartner

  1. MKP-5-mediated regulation of JNK (zeige MAPK8 ELISA Kits) negatively regulates phosphorylation of GRAB, which subsequently controls secretion of IL-6 (zeige IL6 ELISA Kits)

  2. DUSP10 regulates intestinal epithelial cell growth and colorectal tumorigenesis.

  3. In mouse macrophages, MKP-5 down-regulates the release of inflammatory mediators by controlling p38 MAPK (zeige MAPK14 ELISA Kits) activity

  4. These results suggest that p38 (zeige CRK ELISA Kits) phosphorylation is controlled by DUSP10 expression.

  5. MAPK (zeige MAPK1 ELISA Kits) phosphotase 5 deficiency contributes to protection against blood-stage Plasmodium yoelii 17XL infection in mice.

  6. MKP-5 is an essential negative regulator of the promyogenic actions of the MAPKs and may serve as a target to promote muscle stem cell function in the treatment of degenerative skeletal muscle diseases

  7. MKP5 deficiency significantly reduces foam cell formation.

  8. MKP5 is crucial to homeostatic regulation of MAPK (zeige MAPK1 ELISA Kits) activation in inflammatory responses.

  9. a function for ASC (zeige STS ELISA Kits) that is distinct from the inflammasome in modulating MAPK (zeige MAPK1 ELISA Kits) activity and chemokine (zeige CCL1 ELISA Kits) expression and further identify DUSP10 as a novel ASC (zeige STS ELISA Kits) target.

  10. MKP5 has a principal function in both innate and adaptive immune responses, and represents a novel target for therapeutic intervention of immune diseases

Dual Specificity Phosphatase 10 (DUSP10) Antigen-Profil

Beschreibung des Gens

Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAPKs, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK, but not MAPK/ERK. Its subcellular localization is unique\; it is evenly distributed in both the cytoplasm and the nucleus. This gene is widely expressed in various tissues and organs, and its expression is elevated by stress stimuli. Three transcript variants encoding two different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit DUSP10

  • dual specificity phosphatase 10 (DUSP10) Antikörper
  • dual specificity phosphatase 10 (LOC100227773) Antikörper
  • dual specificity phosphatase 10 (Dusp10) Antikörper
  • 2610306G15Rik Antikörper
  • AI158871 Antikörper
  • DUSP10 Antikörper
  • Mkp-5 Antikörper
  • Mkp5 Antikörper

Bezeichner auf Proteinebene für DUSP10

dual specificity protein phosphatase 10 , dual specificity phosphatase 10 , dual specificity protein phosphatase 10-like , dual specificity phosphatase MKP-5 , map kinase phosphatase 5 , mitogen-activated protein kinase phosphatase 5 , serine/threonine specific protein phosphatase , MAP kinase phosphatase 5

421340 Gallus gallus
469145 Pan troglodytes
488673 Canis lupus familiaris
705056 Macaca mulatta
100018106 Monodelphis domestica
100081167 Ornithorhynchus anatinus
100352279 Oryctolagus cuniculus
100411494 Callithrix jacchus
100451135 Pongo abelii
100478038 Ailuropoda melanoleuca
100517416 Sus scrofa
100227773 Taeniopygia guttata
100588389 Nomascus leucogenys
11221 Homo sapiens
63953 Mus musculus
63995 Rattus norvegicus
541175 Bos taurus
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