anti-Dual Specificity Phosphatase 10 (DUSP10) Antikörper

Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. Zusätzlich bieten wir Ihnen Dual Specificity Phosphatase 10 Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
DUSP10 11221 Q9Y6W6
DUSP10 63953 Q9ESS0
DUSP10 63995  
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Top anti-Dual Specificity Phosphatase 10 Antikörper auf antikoerper-online.de

Showing 10 out of 99 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-DUSP10 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>THP-1 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Ziege Unkonjugiert ELISA, WB ABIN184694 staining (0.5µg/ml) of Human Liver lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Kaninchen Unkonjugiert WB DUSP10 Antibody (Center) (ABIN1881272) western blot analysis in A375 cell line lysates (35 µg/lane). This demonstrates the DUSP10 antibody detected the DUSP10 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Rind (Kuh) Ziege Unkonjugiert WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$455.40
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Fledermaus Ziege Unkonjugiert WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$610.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of anti-DUSP10 Pab (ABIN392871) in CEM cell line tissue lysate (35 µg/lane). DUSP10(arrow) was detected using the purified polyclonal antibody (1:60 dilution). Western blot analysis of anti-DUSP10 Pab (ABIN392871) in mouse heart tissue lysates (35 µg/lane). DUSP10(arrow) was detected using the purified polyclonal antibody (1:60 dilution). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded A549 xenograft, using DUSP10, antibody at 1:100 dilution. ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed A431, using DUSP10, antibody at 1:200 dilution. 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details

DUSP10 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Dual Specificity Phosphatase 10 Antikörper

  1. Human Polyclonal DUSP10 Primary Antibody für WB - ABIN1881272 : Tephly, Carter: Asbestos-induced MKP-3 expression augments TNF-alpha gene expression in human monocytes. in American journal of respiratory cell and molecular biology 2008 (PubMed)
    Show all 5 Pubmed References

  2. Human Polyclonal DUSP10 Primary Antibody für ELISA, WB - ABIN257848 : Kadoya, Khurana, Tcherpakov, Bromberg, Didier, Broday, Asahara, Bhoumik, Ronai: JAMP, a Jun N-terminal kinase 1 (JNK1)-associated membrane protein, regulates duration of JNK activity. in Molecular and cellular biology 2005 (PubMed)
    Show all 2 Pubmed References

  3. Cow (Bovine) Polyclonal DUSP10 Primary Antibody für WB - ABIN2785082 : Teng, Huang, Meng: Several dual specificity phosphatases coordinate to control the magnitude and duration of JNK activation in signaling response to oxidative stress. in The Journal of biological chemistry 2007 (PubMed)

  4. Human Polyclonal DUSP10 Primary Antibody für ELISA, WB - ABIN564881 : Wang, Daouti, Li, Wen, Rizzo, Higgins, Packman, Rosen, Boylan, Heimbrook, Niu: Identification of the MEK1(F129L) activating mutation as a potential mechanism of acquired resistance to MEK inhibition in human cancers carrying the B-RafV600E mutation. in Cancer research 2011 (PubMed)

Weitere Antikörper gegen Dual Specificity Phosphatase 10 Interaktionspartner

Human Dual Specificity Phosphatase 10 (DUSP10) Interaktionspartner

  1. High DUSP10 expression is associated with Metastasis of Hepatocellular Carcinoma.

  2. This study demonstrates that AGR2 (zeige AGR2 Antikörper), which is overexpressed in a variety of human cancers and provides a poor prognosis, up-regulates DUSP10 which subsequently inhibits p38 MAPK (zeige MAPK14 Antikörper) and prevents p53 (zeige TP53 Antikörper) activation by phosphorylation.

  3. Increased Dusp10 expression is associated with better survival rate in colorectal cancer patients.

  4. Data suggest that vitamin D receptor (zeige VDR Antikörper) target genes (DUSP10; THBD (zeige THBD Antikörper), thrombomodulin (zeige THBD Antikörper); NRIP1 (zeige NRIP1 Antikörper), nuclear receptor interacting protein 1 (zeige NRIP1 Antikörper); TRAK1 (zeige TRAK1 Antikörper), trafficking protein kinesin binding 1 (zeige TRAK1 Antikörper)) can be used as markers for individual's response to vitamin D3 supplements.

  5. Certain mutations in DUSP10 correlate with the incidence of colorectal cancer(CRC). Thus, the function of the DUSP10 gene product may contribute toward CRC in the Han Chinese population.

  6. Single nucleotide polymorphism in DUSP10 gene is associated with celiac disease.

  7. Depletion of miR (zeige MLXIP Antikörper)-181 family members by miRNA inhibitors enhanced the expression of MKP-5 and suppressed the phosphorylation of p38 MAPK (zeige MAPK14 Antikörper) after exposure to PAHs, which promotes cancer cell migration.

  8. Data indicate that the activities of phosphoprotein phosphatases MKP5 and MKP7 (zeige DUSP16 Antikörper) were determined in the system.

  9. MKP-5 interacts with ERK (zeige EPHB2 Antikörper), retains it in the cytoplasm, suppresses its activation and downregulates ERK (zeige EPHB2 Antikörper)-dependent transcription.

  10. A distinct interaction mode revealed by the crystal structure of the kinase p38alpha (zeige MAPK14 Antikörper) with the MAPK (zeige MAPK1 Antikörper) binding domain of the phosphatase MKP5.

Mouse (Murine) Dual Specificity Phosphatase 10 (DUSP10) Interaktionspartner

  1. MKP-5-mediated regulation of JNK (zeige MAPK8 Antikörper) negatively regulates phosphorylation of GRAB, which subsequently controls secretion of IL-6 (zeige IL6 Antikörper)

  2. DUSP10 regulates intestinal epithelial cell growth and colorectal tumorigenesis.

  3. In mouse macrophages, MKP-5 down-regulates the release of inflammatory mediators by controlling p38 MAPK (zeige MAPK14 Antikörper) activity

  4. These results suggest that p38 (zeige CRK Antikörper) phosphorylation is controlled by DUSP10 expression.

  5. MAPK (zeige MAPK1 Antikörper) phosphotase 5 deficiency contributes to protection against blood-stage Plasmodium yoelii 17XL infection in mice.

  6. MKP-5 is an essential negative regulator of the promyogenic actions of the MAPKs and may serve as a target to promote muscle stem cell function in the treatment of degenerative skeletal muscle diseases

  7. MKP5 deficiency significantly reduces foam cell formation.

  8. MKP5 is crucial to homeostatic regulation of MAPK (zeige MAPK1 Antikörper) activation in inflammatory responses.

  9. a function for ASC (zeige STS Antikörper) that is distinct from the inflammasome in modulating MAPK (zeige MAPK1 Antikörper) activity and chemokine (zeige CCL1 Antikörper) expression and further identify DUSP10 as a novel ASC (zeige STS Antikörper) target.

  10. MKP5 has a principal function in both innate and adaptive immune responses, and represents a novel target for therapeutic intervention of immune diseases

Dual Specificity Phosphatase 10 (DUSP10) Antigen-Profil

Protein Überblick

Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAPKs, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK, but not MAPK/ERK. Its subcellular localization is unique\; it is evenly distributed in both the cytoplasm and the nucleus. This gene is widely expressed in various tissues and organs, and its expression is elevated by stress stimuli. Three transcript variants encoding two different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit DUSP10

  • dual specificity phosphatase 10 (DUSP10) Antikörper
  • dual specificity phosphatase 10 (Dusp10) Antikörper
  • 2610306G15Rik Antikörper
  • AI158871 Antikörper
  • DUSP10 Antikörper
  • Mkp-5 Antikörper
  • Mkp5 Antikörper

Bezeichner auf Proteinebene für DUSP10

dual specificity protein phosphatase 10 , dual specificity phosphatase 10 , dual specificity protein phosphatase 10-like , dual specificity phosphatase MKP-5 , map kinase phosphatase 5 , mitogen-activated protein kinase phosphatase 5 , serine/threonine specific protein phosphatase , MAP kinase phosphatase 5

GENE ID SPEZIES
421340 Gallus gallus
469145 Pan troglodytes
488673 Canis lupus familiaris
705056 Macaca mulatta
100018106 Monodelphis domestica
100081167 Ornithorhynchus anatinus
100352279 Oryctolagus cuniculus
100411494 Callithrix jacchus
100451135 Pongo abelii
100478038 Ailuropoda melanoleuca
100517416 Sus scrofa
100227773 Taeniopygia guttata
100588389 Nomascus leucogenys
11221 Homo sapiens
63953 Mus musculus
63995 Rattus norvegicus
541175 Bos taurus
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