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DAGLA encodes a diacylglycerol lipase. Zusätzlich bieten wir Ihnen DAGLA Antikörper (58) und DAGLA Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.
phenotypes associated with rare CNR1 (zeige CNR1 ELISA Kits) variants are reminiscent of those implicated in the theory of clinical endocannabinoid deficiency syndrome. The severe phenotypes associated with rare DAGLA variants underscore the critical role of rapid 2-AG synthesis and the endocannabinoid system in regulating neurological function and development
In subcutaneous adipose tissue, DAGL-a mRNA was upregulated and fatty acid amide hydrolase (FAAH (zeige FAAH ELISA Kits)) and monoacylglycerol lipase (MAGL (zeige MGLL ELISA Kits)) mRNAs were down-regulated in obese subjects, but the diets had no influence.
PLC (zeige HSPG2 ELISA Kits)-beta1 and DAGL-alpha are detected in discrete brain regions, with a marked predominance of pyramidal morphologies of positive cortical cells.[review]
DAGLalpha mRNA expression is lowest in early life and adulthood, peaking between school age and young adulthood.
This gene was functionally characterized as a diacylglycerol-lipase (zeige LIPG ELISA Kits) (DAGL), specifically referred to as DAGL alpha. This enzyme may play a role in the biosynthesis of the endocannbinoid 2-arachidonoylglycerol (2-AG).
Results demonstrate that mice with a deletion of the DAGL-alpha enzyme show a phenotype of increased emotional or stress-related behaviors. This is characterized by a reduced exploration of the central area of the open field, a maternal neglect behavior, a fear extinction deficit, increased behavioral despair, increased anxiety-related behaviors in the light/dark box, and reduced hippocampal neurogenesis
Authors demonstrated that phospholipase D (zeige PLD ELISA Kits) and diacylglycerol lipase (zeige LIPG ELISA Kits) were required for providing arachidonic acid for prostaglandin E(2) biosynthesis.
In corpus striatum diacylglycerol lipase-alpha activity is regulated by calcium/calmodulin dependent protein kinase (CaMK-II (zeige CAMK2 ELISA Kits)).
DAGLalpha is the major biosynthetic enzyme for 2-AG in the nervous system and reveal an essential role for this enzyme in regulating retrograde synaptic plasticity and adult neurogenesis.
This gene encodes a diacylglycerol lipase. The encoded enzyme is involved in the biosynthesis of the endocannabinoid 2-arachidonoyl-glycerol.
diacylglycerol lipase, alpha
, neural stem cell-derived dendrite regulator
, sn1-specific diacylglycerol lipase alpha-like
, sn1-specific diacylglycerol lipase alpha