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Diacylglycerol kinases are thought to be involved mainly in the regeneration of phosphatidylinositol (PI) from diacylglycerol in the PI-cycle during cell signal transduction. Zusätzlich bieten wir Ihnen DGKE Proteine (8) und DGKE Kits (1) und viele weitere Produktgruppen zu diesem Protein an.
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Our results unveil an unexpected role of Dgke in the induction of cyclooxygenase-2 (zeige PTGS2 Antikörper) and in the regulation of glomerular prostanoids synthesis under stress
Inhibition of lipid signaling enzyme diacylglycerol kinase epsilon attenuates mutant huntingtin (zeige HTT Antikörper) toxicity.
A regulatory role is suggested for DGK epsilon, COX-2 (zeige COX2 Antikörper), and catecholamine signaling during kindling epileptogenesis.
Letter/Case Report: atypical haemolytic uraemic syndrome in a Japanese patient with DGKE genetic mutations.
Report DGKE intronic mutations located beyond the exon-intron boundaries in familial hemolytic uremic syndrome.
Data suggest that complement dysregulation influences the onset and disease severity in carriers of diacylglycerol kinase-epsilon mutations
DGKE silencing in resting endothelial cells does not affect complement activation at their surface.
Our study expands the clinical phenotypes associated with mutations in DGKE and challenges the benefits of complement blockade treatment in such patients
DGKzeta (zeige DGKZ Antikörper) localizes to the nucleus and is considered to regulate nuclear diacylglycerol signaling.[review]
Fully activating high-density transfected muscarinic receptors (M1Rs) by oxotremorine-M (Oxo-M) leads to similar calcium, DAG, and PKC signals, but PIP2 is depleted.
Recessive mutations in DGKE cause atypical hemolytic-uremic syndrome.
Substrate specificity of DGKE is not a consequence of competition with hydrolysis of ATP.
performed homozygosity mapping and whole exome sequencing in a Turkish consanguineous family and identified DGKE gene variants as the cause of a membranoproliferative-like glomerular microangiopathy
Diacylglycerol kinases are thought to be involved mainly in the regeneration of phosphatidylinositol (PI) from diacylglycerol in the PI-cycle during cell signal transduction. When expressed in mammalian cells, DGK-epsilon shows specificity for arachidonyl-containing diacylglycerol. DGK-epsilon is expressed predominantly in testis.
diacylglycerol kinase, epsilon 64kDa
, diacylglycerol kinase epsilon
, diacylglycerol kinase epsilon-like
, diacylglycerol kinase, epsilon
, DAG kinase epsilon
, diglyceride kinase epsilon