anti-Desmoglein 3 (DSG3) Antikörper

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Zusätzlich bieten wir Ihnen Desmoglein 3 Kits (17) und Desmoglein 3 Proteine (11) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
DSG3 1830 P32926
DSG3 13512  
DSG3 291752  
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Top anti-Desmoglein 3 Antikörper auf antikoerper-online.de

Showing 10 out of 174 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of Desmoglein-3 Antibody (N-term) in WiDr cell line lysates (35ug/lane). This demonstrates the DSG3 antibody detected the DSG3 protein (arrow). 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Maus Unkonjugiert ICC, FACS, IF, IHC (p), IP, IHC, WB 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$485.88
Details
Human Maus Unkonjugiert IHC (fro), WB   5 mL Anmelden zum Anzeigen 6 bis 8 Tage
$357.50
Details
Human Maus Unkonjugiert ICC, IF, IHC, IHC (p), IP, WB Western Blot: Desmoglein-3 Antibody (5H10) [NBP1-78984] - Analysis of Desmoglein 3 expression in HaCat cell lysate using NBP1-78984. Immunohistochemistry: Desmoglein-3 Antibody (5H10) [NBP1-78984] - Analysis of Desmoglein 3 on human skin cancer using NBP1-78984. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$415.44
Details
Human Kaninchen Unkonjugiert WB WB Suggested Anti-DSG3 AntibodyTitration: 1.0 µg/mL <br /> Positive Control: HepG2 Whole Cell 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Maus Unkonjugiert IHC (fro), IF, IHC (p), IP, WB   0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$467.50
Details
Human Kaninchen Unkonjugiert WB Anti-Desmoglein 3 antibody, Western blotting Lane 1: A431 Cell Lysate Lane 2: CEM Cell Lysate 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$200.00
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p) Formalin-fixed and paraffin embedded rat tongue labeled with Anti-Desmoglein 3/DSG3 Polyclonal Antibody, Unconjugated (ABIN718451) at 1:200 followed by conjugation to the secondary antibody 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$318.45
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of Desmoglein 3 expression in A431 (A), HeLa (B), Raw264.7 (C), PC12 (D) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Maus Unkonjugiert IF, IHC (p), IP, WB   1 mL Anmelden zum Anzeigen 11 bis 16 Tage
$1,027.40
Details

DSG3 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Desmoglein 3 Antikörper

  1. Human Monoclonal Desmoglein 3 Primary Antibody für ICC, IF - ABIN4305016 : Proby, Ota, Suzuki, Koyasu, Gamou, Shimizu, Wahl, Wheelock, Nishikawa, Amagai: Development of chimeric molecules for recognition and targeting of antigen-specific B cells in pemphigus vulgaris. in The British journal of dermatology 2000 (PubMed)
    Show all 7 Pubmed References

  2. Human Monoclonal Desmoglein 3 Primary Antibody für ICC, FACS - ABIN151179 : Wu, Stanley, Cotsarelis: Desmoglein isotype expression in the hair follicle and its cysts correlates with type of keratinization and degree of differentiation. in The Journal of investigative dermatology 2003 (PubMed)
    Show all 6 Pubmed References

  3. Human Monoclonal Desmoglein 3 Primary Antibody für IHC (fro), IP - ABIN2473333 : Smith, Richards, Yasin, Sangster, Sridaran: Changes in rat luteal ultrastructure and P450scc mRNA and protein content after in vivo treatment with a gonadotropin-releasing hormone agonist. in Biology of reproduction 1991 (PubMed)
    Show all 4 Pubmed References

  4. Human Monoclonal Desmoglein 3 Primary Antibody für FACS, IF - ABIN5576864 : Mahoney, Hu, Brennan, Bazzi, Christiano, Wahl: Delineation of diversified desmoglein distribution in stratified squamous epithelia: implications in diseases. in Experimental dermatology 2006 (PubMed)

Weitere Antikörper gegen Desmoglein 3 Interaktionspartner

Human Desmoglein 3 (DSG3) Interaktionspartner

  1. Desmoglein 3 Order and Dynamics in Desmosomes

  2. Data indicate that all 3 monoclonal antibodies (mAbs) targeted the same extracellular cadherin (EC) domain on desmoglein 3 (Dsg3), caused Dsg3 internalization in primary keratinocytes, and caused suprabasal blisters in skin.

  3. DSG3 was a key prognostic factor and predictor for neoadjuvant concurrent chemoradiotherapy response in rectal cancer patients.

  4. Treg cells exert a clear down-regulatory effect on the Dsg3-driven T-cell response and, accordingly, the formation of Dsg3-specific IgG antibodies

  5. Data identify DSG3 as a negative prognostic biomarker in resected pancreatic ductal adenocarcinoma, as high DSG3 expression is associated with poor overall survival and poor tumour-specific survival.

  6. this study directly demonstrates the occurrence of desmoglein 3 molecules outside of desmosomes and reveales that the adhesive properties of these molecules do differ depending on their localization.

  7. DSG2 (zeige DSG2 Antikörper) and DSG3 might be potential diagnostic markers for squamous cell carcinoma of the lung and DSG3 could be a potential differentiation marker for lung cancer.

  8. alterations of their expression suggest a role of Dsg3 and gamma-catenin (zeige JUP Antikörper) (additionally to E-cadherin (zeige CDH1 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper)) as biomarkers of malignant transformation risk of oral dysplasia and the biological behavior (aggressiveness) of oral cancer, respectively

  9. In endometrial luminal epithelium, cadherin 6 (zeige CDH6 Antikörper), desmoglein 2 (zeige DSG2 Antikörper) and plexin b2 (zeige PLXNB2 Antikörper) were surprisingly found in the apical as well as the lateral membrane domain; their knock-down compromised epithelial integrity.

  10. the Dsg3 epitopes targeted by pathogenic mPV IgG are human specific in mice

Mouse (Murine) Desmoglein 3 (DSG3) Interaktionspartner

  1. Desmoglein 3 deficiency in mice leads to a phenotype characterized by cyclic alopecia in addition to the dramatic skin and mucocutaneous acantholysis observed in pemphigus patients.

  2. Dsg3, via p38 MAPK (zeige MAPK14 Antikörper), regulates the spatial distribution of the keratin filament network and stabilizes cell adhesion.

  3. Squamous metaplasia after pulmonary epithelial injury may play a crucial role in redirecting the skin-specific autoimmune reaction to the lungs in paraneoplastic pemphigus (PNP (zeige NP Antikörper)).

  4. Dsg3 deficiency results in perturbation of the desmosomal network at the transcriptional, translational, and interaction level, kinase activation, proteinase-mediated degradation, and hyper-adhesion. (Review)

  5. Thus, Dsg3 does not display a clear function as a tumor suppressor in these mouse skin cancer models

  6. IgG and IgM (zeige CD40LG Antikörper) antibodies against desmoglein 3 have a pathogenic role in blister formation in pemphigus vulgaris

  7. the adult passive transfer mouse model is ideally suited for detailed studies of Dsg3 antibody-mediated signaling in adult skin.

  8. These data indicate a contribution of Dsg (zeige DSG1 Antikörper) depletion to pemphigus vulgaris pathogenesis dependent on Ca(2 (zeige CA2 Antikörper)+)-induced differentiation.

  9. Transgenic expression of Dsg1 (zeige DSG1 Antikörper) rescued the severe B6-Dsg3(-/-) phenotype and provided a syngeneic mouse model of pemphigus vulgaris.

  10. Aire (zeige AIRE Antikörper) has an important role in Dsg3 expression as well as in selection of T cells that help B cells to produce anti-Dsg3 IgG in thymus.

Desmoglein 3 (DSG3) Antigen-Profil

Protein Überblick

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.

Genbezeichner und Symbole assoziert mit anti-Desmoglein 3 (DSG3) Antikörper

  • desmoglein 3 (DSG3) Antikörper
  • desmoglein 3 (Dsg3) Antikörper
  • bal Antikörper
  • balding Antikörper
  • CDHF6 Antikörper
  • DSG3 Antikörper
  • PVA Antikörper

Bezeichner auf Proteinebene für anti-Desmoglein 3 (DSG3) Antikörper

desmoglein 3 (pemphigus vulgaris antigen) , desmoglein-3 , desmoglein 3 , 130 kDa pemphigus vulgaris antigen , 130-kD pemphigus vulgaris antigen , cadherin family member 6 , pemphigus vulgaris antigen , 130 kDa pemphigus vulgaris antigen homolog , desmoglein 3 preprotein

GENE ID SPEZIES
468511 Pan troglodytes
529902 Bos taurus
705685 Macaca mulatta
100347905 Oryctolagus cuniculus
100590729 Nomascus leucogenys
1830 Homo sapiens
13512 Mus musculus
291752 Rattus norvegicus
403470 Canis lupus familiaris
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