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The protein encoded by DSC1 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. Zusätzlich bieten wir Ihnen Desmocollin 1 Antikörper (66) und Desmocollin 1 Proteine (10) und viele weitere Produktgruppen zu diesem Protein an.
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DSC1 (zeige RCAN1 ELISA Kits) expression is significantly downregulated in human masticatory mucosa during wound healing
Increased expression of DSC1 (zeige RCAN1 ELISA Kits) can promote the occurrence of head and neck squamous cell carcinoma (HNSCC) and is associated with tumor. The increased expression of DSC1 (zeige RCAN1 ELISA Kits) also indicates a poor prognosis of the patients with HNSCC.
Low expression of DSC 1 (zeige RCAN1 ELISA Kits), 2, and 3 was observed in 55, 54, and 79 % of liver metastases.
High expression of desmocollin 1 (DSC1) was observed in 41.6%, DSC2 (zeige DSC2 ELISA Kits) in 58.0%, DSC3 (zeige DSC2 ELISA Kits) in 61.4%, E-cadherin (zeige CDH1 ELISA Kits) in 71.4%, CDX2 (zeige CDX2 ELISA Kits) in 58.0%, PITX1 (zeige PITX1 ELISA Kits) in 55.0%, CDK4 (zeige CDK4 ELISA Kits) in 0.2%, TLE1 in 1.3%, Factor H (zeige CFH ELISA Kits) in 42.5%, and MDM2 (zeige MDM2 ELISA Kits) in 0.2% of colorectal carcinomas.
The ultrastructural modifications of desmosomes during terminal differentiation of hair follicles are paralleled by the modulation of the synthesis of desmocollin 1.
in majority of patients with Netherton syndrome, Dsg1 (zeige DSG1 ELISA Kits) & Dsc1 (zeige RCAN1 ELISA Kits) were reduced in living layers of epidermis; SCTE (zeige KLK5 ELISA Kits)-like & SCCE (zeige KLK7 ELISA Kits)-like activities were increased, suggesting these proteases participate in premature degradation of corneodesmosomal cadherins
Increased Dsc1 (zeige RCAN1 ELISA Kits) protein is associated with colorectal cancer
The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms.
, cadherin family member 1
, desmosomal glycoprotein 2/3