anti-Deoxyribonuclease II, Lysosomal (DNASE2) Antikörper

The protein encoded by DNASE2 shares considerable sequence similarity to, and is structurally related to DNase II. Zusätzlich bieten wir Ihnen Deoxyribonuclease II, Lysosomal Proteine (10) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
DNASE2 13423 P56542
DNASE2 1777 O00115
DNASE2 171575 Q9QZK8
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Showing 10 out of 53 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC (p), WB 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
385,00 €
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Human Kaninchen Unkonjugiert IHC (p), WB 0.1 mg Anmelden zum Anzeigen 4 bis 5 Tage
349,41 €
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Human Kaninchen Unkonjugiert IF (p), IHC (p) Formalin-fixed and paraffin embedded human laryngocarcinoma labeled with Anti-DNase II Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining. Formalin-fixed and paraffin embedded human laryngocarcinoma labeled with Anti-DNase II Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
304,36 €
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Human Kaninchen Unkonjugiert ELISA, ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: DNase II Antibody [NBP1-76971] - Human spleen tissue with DNaseII antibody at 5 ug/ml. Western Blot: DNase II Antibody [NBP1-76971] - Analysis of Dnase II using NBP1-76971 at 2 ug/ml against 10 ug/lane of human spleen tissue lysate in the absence (lane 1) or presence (lane 2) of blocking peptide with DNase II at 1:500 dilution. 0.1 mg Anmelden zum Anzeigen 3 bis 6 Tage
341,00 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB Human Thymus (formalin-fixed, paraffin-embedded) stained with DNASE2 antibody ABIN214485 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with DNASE2 antibody ABIN214485 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
501,70 €
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Human Kaninchen Unkonjugiert IHC (p), WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
517,00 €
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Human Kaninchen Alexa Fluor 594 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen Alexa Fluor 350 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen Alexa Fluor 488 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen Alexa Fluor 555 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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DNASE2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Deoxyribonuclease II, Lysosomal Antikörper

  1. Human Polyclonal DNASE2 Primary Antibody für IHC (p), WB - ABIN2473351 : Yasuda, Takeshita, Iida, Nakajima, Hosomi, Nakashima, Kishi: Molecular cloning of the cDNA encoding human deoxyribonuclease II. in The Journal of biological chemistry 1998 (PubMed)
    Zeige alle 4 Referenzen für 2473351

  2. Human Polyclonal DNASE2 Primary Antibody für IHC (p), WB - ABIN318974 : Krieser, Eastman: The cloning and expression of human deoxyribonuclease II. A possible role in apoptosis. in The Journal of biological chemistry 1998 (PubMed)
    Zeige alle 3 Referenzen für 318974

Weitere Antikörper gegen Deoxyribonuclease II, Lysosomal Interaktionspartner

Fruit Fly (Drosophila melanogaster) Deoxyribonuclease II, Lysosomal (DNASE2) Interaktionspartner

  1. These results confirm that DNase II and the ability to clear macromolecular DNA is essential for maintaining proper immune function in Drosophila.

  2. findings indicate that DNaseII can act cell autonomously to degrade DNA during nonapoptotic cell death.

Mouse (Murine) Deoxyribonuclease II, Lysosomal (DNASE2) Interaktionspartner

  1. holocrine secretion is a DNase2-mediated form of programmed cell death and suggest that autophagy-dependent metabolism, DNA degradation

  2. Data show that Klf1 (zeige KLF1 Antikörper) is expressed in central macrophagse of erythroblastic islands and that it binds and activates the promoter of Dnase2a.

Human Deoxyribonuclease II, Lysosomal (DNASE2) Interaktionspartner

  1. Single nucleotide polymorphisms producing a loss-of-function variant of the enzymes in DNASE1 (zeige DNASE1 Antikörper), DNASE1L3 (zeige DNASE1L3 Antikörper), and DNASE2, possibly serving as a genetic risk factor for autoimmune diseases, were confirmed.

  2. 15 nonsynonymous human DNase II SNPs were genotyped in three ethnic groups including 16 different populations using the PCR-restriction fragment length polymorphism technique.

  3. study demonstrated the relationship of genotypes/haplotypes with the in vivo DNase II and promoter activities; significant correlations between genotype in each rheumatoid arthritis (RA)-related SNP and enzymatic activity levels were found; alleles associated with RA exhibited a reduction in serum DNase II activity.

  4. upregulation of expression during myelomonocytic differentiation of HL-60 and THP-1 (zeige GLI2 Antikörper) cells

  5. Sp1 (zeige PSG1 Antikörper) and Sp3 (zeige SP3 Antikörper) are involved in up-regulation of this enzyme's transcriptoin during cell differentiation of hl-60 cells.

  6. the enzyme is a monomeric phospholipase D (zeige PLD Antikörper)-family member with a pseudodimeric protein fold

  7. The association of SNPs in the 5'-regulatory region of the DNA degrading enzyme DNASE2 with Rheumatoid Arthritis implies a role for this enzyme in the pathogenesis of this autoimmune disease.

Pig (Porcine) Deoxyribonuclease II, Lysosomal (DNASE2) Interaktionspartner

  1. Proteolytic processing of porcine deoxyribonuclease II occurs in lysosomes but is not required for enzyme activation

  2. Data showed an association between PARP-1 and LEI/L-DNase II.

Deoxyribonuclease II, Lysosomal (DNASE2) Antigen-Profil

Protein Überblick

This gene encodes a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record.

Genbezeichner und Symbole assoziert mit DNASE2

  • Deoxyribonuclease II (DNaseII) Antikörper
  • deoxyribonuclease II, lysosomal (dnase2) Antikörper
  • deoxyribonuclease II, lysosomal (DNASE2) Antikörper
  • deoxyribonuclease II, lysosomal (LOC733868) Antikörper
  • deoxyribonuclease II (dnase2) Antikörper
  • deoxyribonuclease II alpha (Dnase2a) Antikörper
  • deoxyribonuclease II, lysosomal (Dnase2) Antikörper
  • CG7780 Antikörper
  • DDBDRAFT_0188966 Antikörper
  • DDBDRAFT_0252883 Antikörper
  • DDB_0188966 Antikörper
  • DDB_0252883 Antikörper
  • dDNase II Antikörper
  • Dmel\\CG7780 Antikörper
  • DNase Antikörper
  • DNase-1 Antikörper
  • DNase1 Antikörper
  • DNase 1 Antikörper
  • Dnase2 Antikörper
  • Dnase2a Antikörper
  • DNL Antikörper
  • DNL2 Antikörper
  • fa92d01 Antikörper
  • LOC733868 Antikörper
  • MGC80103 Antikörper
  • wu:fa56d08 Antikörper
  • wu:fa92d01 Antikörper

Bezeichner auf Proteinebene für DNASE2

deoxyribonuclease II , CG7780-PA , DNaseII-PA , acid DNase , deoxyribonuclease 1 , deoxyribonuclease II, lysosomal , deoxyribonuclease-2-alpha , fa56d08 , DNase II alpha , lysosomal DNase II , DNase II, lysosomal , R31240_2 , deoxyribonuclease II alpha

GENE ID SPEZIES
48228 Drosophila melanogaster
446506 Xenopus laevis
476697 Canis lupus familiaris
733868 Xenopus (Silurana) tropicalis
747576 Pan troglodytes
100000399 Danio rerio
100171654 Pongo abelii
100599185 Nomascus leucogenys
8627734 Dictyostelium discoideum AX4
13423 Mus musculus
1777 Homo sapiens
171575 Rattus norvegicus
282218 Bos taurus
397398 Sus scrofa
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