anti-Defensin, alpha 5, Paneth Cell-Specific (DEFA5) Antikörper

Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. Zusätzlich bieten wir Ihnen Defensin, alpha 5, Paneth Cell-Specific Kits (54) und Defensin, alpha 5, Paneth Cell-Specific Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
DEFA5 1670 Q01523
DEFA5 13239  
DEFA5 286995 Q62715
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Top anti-Defensin, alpha 5, Paneth Cell-Specific Antikörper auf antikoerper-online.de

Showing 10 out of 56 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Maus Unkonjugiert DB, ICC, FACS, IF, IHC (p), IHC, ELISA, WB Human skeletal muscle myocytes showing moderate nuclear and faint cytoplasmic staining using ABIN258712. Flow Cytometry: Defensin alpha 5 Antibody (8C8) [ABIN2587122] - Intracellular flow cytometric staining of 1 x 10^6 MCF-7 cells using Defensin alpha 5 antibody (dark blue). Isotype control shown in orange. An antibody concentration of 1 ug/1x10^6 cells was used. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$444.19
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Immunohistochemistry-Paraffin: Defensin alpha 5 Antibody [NBP1-84282] - Staining of human small intestine shows strong cytoplasmic positivity in Paneth cells. Immunohistochemistry-Paraffin: Defensin alpha 5 Antibody [NBP1-84282] - Staining of human nasopharynx shows cytoplasmic and membranous positivity in respiratory epithelial cells. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Maus Unkonjugiert IF, IHC (p), WB Human Small Intestine (formalin-fixed, paraffin-embedded) stained with DEFA5 antibody ABIN396940 at 10 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. 50 μL Anmelden zum Anzeigen 7 bis 9 Tage
$595.83
Details
Human Kaninchen Unkonjugiert ICC, IHC, IP, WB Figure.DAB staining on IHC-P. Samples: Human Tissue 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$332.00
Details
Human Maus Unkonjugiert ICC, IHC (fro), IHC (p), ELISA, WB 200 μg Anmelden zum Anzeigen 13 bis 16 Tage
$352.00
Details
Human Maus Unkonjugiert IF, IHC (p), WB 100 μL Anmelden zum Anzeigen 6 bis 7 Tage
$555.07
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$306.90
Details
Human Kaninchen Unkonjugiert WB   100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Maus PerCP DB, ELISA, ICC, IF, IHC, IHC (p), WB   0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$547.69
Details
Human Maus Biotin ELISA, ICC, IF, IHC, IHC (p), WB   0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$556.31
Details

DEFA5 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human , , ,
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Mouse (Murine)


Rat (Rattus)


Am meisten referenzierte anti-Defensin, alpha 5, Paneth Cell-Specific Antikörper

  1. Human Monoclonal DEFA5 Primary Antibody für DB, ICC - ABIN258712 : Wehkamp, Salzman, Porter, Nuding, Weichenthal, Petras, Shen, Schaeffeler, Schwab, Linzmeier, Feathers, Chu, Lima, Fellermann, Ganz, Stange, Bevins: Reduced Paneth cell alpha-defensins in ileal Crohn's disease. in Proceedings of the National Academy of Sciences of the United States of America 2005 (PubMed)
    Show all 9 Pubmed References

  2. Human Monoclonal DEFA5 Primary Antibody für IA, IHC (fro) - ABIN2192079 : Kelly, Bajaj-Elliott, Katubulushi, Zulu, Poulsom, Feldman, Bevins, Dhaliwal: Reduced gene expression of intestinal alpha-defensins predicts diarrhea in a cohort of African adults. in The Journal of infectious diseases 2006 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal DEFA5 Primary Antibody für IHC, IHC (p) - ABIN4304804 : Lee, Nam, Park, Kim, Lafleur, Aburatani, Yang, Kim, Goldenring: Gene expression profiling of metaplastic lineages identifies CDH17 as a prognostic marker in early stage gastric cancer. in Gastroenterology 2010 (PubMed)

Weitere Antikörper gegen Defensin, alpha 5, Paneth Cell-Specific Interaktionspartner

Human Defensin, alpha 5, Paneth Cell-Specific (DEFA5) Interaktionspartner

  1. Human alpha-Defensin-5 is a potential candidate biomarker to molecularly differentiate Crohn's colitis from ulcerative colitis, to our knowledge. These data give us both a potential diagnostic marker in Human alpha-Defensin-5 and insight to develop future mechanistic studies to better understand crypt biology in Crohn's colitis.

  2. Different dynamics and pathway of disulfide bonds reduction has been demonstrated for two human defensins, HD5 and HBD-3 (zeige DEFB103A Antikörper).

  3. Human adenovirus 3 produces large amounts of penton-dodecahedra (PtDd), virus-like particles, during replication, which also function in blocking of HD5.

  4. no biologic differences between wild-type HD5 and its variants were observed on HD5 antibacterial activity against Escherichia coli

  5. a moderately active linear peptide derived from the alpha-defensin (zeige DEF Antikörper) HD5 can be engineered to enhance antimicrobial activity almost comparable to the native peptide.

  6. The study used ion mobility coupled to mass spectrometry to track the structural changes in HD-5 upon disulfide bond reduction.

  7. The study reports the screening of human defensin 5 against the Keio Collection of E. coli strains and shows how this important hostdefense peptide kills bacteria and how bacteria protect themselves against the attack from the human host.

  8. Authors show that although NOD2 (zeige NOD2 Antikörper) by itself can slightly up-regulate expression of HD5 and HD6 (zeige DEFA6 Antikörper), it can strongly down-regulates their expression during differentiation of the Paneth cell lineage mainly by inhibiting activation of the MAPK (zeige MAPK1 Antikörper) pathway.

  9. These data support a model in which HD5 prevents furin (zeige FURIN Antikörper) from accessing human papillomavirus 16 L2 by occluding the furin (zeige FURIN Antikörper) cleavage site via direct binding to the viral capsid.

  10. Enteric alpha-defensin (zeige DEF Antikörper) HD5 and beta-defensin (zeige DEFB1 Antikörper) hBD2 (zeige DEFB4 Antikörper) shared similar toxin-unfolding effects with HNP1 (zeige DEFA1 Antikörper), albeit to different degrees.

Mouse (Murine) Defensin, alpha 5, Paneth Cell-Specific (DEFA5) Interaktionspartner

  1. alpha-defensin 5 expression can also be regulated by microbial metabolites

  2. Data show that DEFA5-expressing mice had striking losses of segmented filamentous bacteria and fewer interleukin 17 (IL-17 (zeige IL17A Antikörper))-producing lamina propria T cells.

Defensin, alpha 5, Paneth Cell-Specific (DEFA5) Antigen-Profil

Protein Überblick

Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several of the alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 5, is highly expressed in the secretory granules of Paneth cells of the ileum.

Genbezeichner und Symbole assoziert mit DEFA5

  • defensin alpha 5 (DEFA5) Antikörper
  • defensin, alpha, 5 (Defa5) Antikörper
  • defensin, alpha 5, Paneth cell-specific (DEFA5) Antikörper
  • defensin alpha 5 (Defa5) Antikörper
  • DEF5 Antikörper
  • Defa Antikörper
  • DEFA1 Antikörper
  • DEFA5 Antikörper
  • Defa29 Antikörper
  • Defcr5 Antikörper
  • Defcr29 Antikörper
  • HD-5 Antikörper

Bezeichner auf Proteinebene für DEFA5

HD5(20-94) , defensin 5 , defensin, alpha 5, preproprotein , defensin-5 , alpha-defensin 5 , defensin, alpha, 29 , defensin-related cryptdin-5 , alpha-defensin 5, Paneth cell-specific , defensin, alpha 1 , Paneth cell-specific alpha-defensin 5 , defensin NP-2 , neutrophil antibiotic peptide NP-1 , neutrophil antibiotic peptide NP-2 , neutrophil defensin 1 , neutrophil defensin 2 , ratNP-1 , ratNP-2

GENE ID SPEZIES
1670 Homo sapiens
13239 Mus musculus
463972 Pan troglodytes
100307028 Equus caballus
286995 Rattus norvegicus
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