anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) Antikörper

DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Zusätzlich bieten wir Ihnen DNA (Cytosine-5)-Methyltransferase 1 Kits (25) und DNA (Cytosine-5)-Methyltransferase 1 Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
DNMT1 1786 P26358
DNMT1 84350  
DNMT1 13433 P13864
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Top anti-DNA (Cytosine-5)-Methyltransferase 1 Antikörper auf antikoerper-online.de

Showing 10 out of 475 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert EIA 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p) Formalin-fixed and paraffin embedded mouse lymphoma tissue labeled with Anti-Dnmt1 Polyclonal Antibody, Unconjugated (ABIN671796) at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-Dnmt1 Polyclonal Antibody, Unconjugated (ABIN671796) at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
315,94 €
Details
Human Kaninchen Unkonjugiert DB Dot blot analysis of anti-Dnmt1 Phospho-specific Pab (ABIN389901) on nitrocellulose membrane.  50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 µg/mL. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of DNMT1 Antibody (S1105) (ABIN387879) in MDA-MB435 cell line lysates (35 µg/lane). DNMT1 (arrow) was detected using the purified polyclonal antibody. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert EIA, WB 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert FACS, WB The anti-Dnmt1 C-term Pab (ABIN387878) is used in Western blot to detect Dnmt1 in Jurkat cell lysate. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert DB Dot blot analysis of anti-Phospho-Dnmt1-pS154 Antibody (ABIN389917) on nitrocellulose membrane.  50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 µg/mL. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Fisch Maus Unkonjugiert ChIP, IP, IHC, WB Dnmt1, 18ug H1299 lysate 1 in1000 Western Blotting. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
411,87 €
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Fisch Maus Unkonjugiert ChIP, IP, IHC, WB Dnmt1, 18ug H1299 lysate 1 in1000 Western Blotting. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
411,87 €
Details

DNMT1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-DNA (Cytosine-5)-Methyltransferase 1 Antikörper

  1. Human Polyclonal DNMT1 Primary Antibody für FACS, WB - ABIN387878 : Peterson, Bögler, Taylor: p53-mediated repression of DNA methyltransferase 1 expression by specific DNA binding. in Cancer research 2003 (PubMed)
    Zeige alle 7 Referenzen für 387878

  2. Human Polyclonal DNMT1 Primary Antibody für WB - ABIN387879 : Leu, Rahmatpanah, Shi, Wei, Liu, Yan, Huang: Double RNA interference of DNMT3b and DNMT1 enhances DNA demethylation and gene reactivation. in Cancer research 2003 (PubMed)
    Zeige alle 7 Referenzen für 387879

  3. Fish Monoclonal DNMT1 Primary Antibody für ChIP, IP - ABIN1027706 : Bestor, Laudano, Mattaliano, Ingram: Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases. in Journal of molecular biology 1989 (PubMed)
    Zeige alle 6 Referenzen für 1027706

  4. Fish Monoclonal DNMT1 Primary Antibody für ChIP, IP - ABIN361726 : Okano, Bell, Haber, Li: DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. in Cell 1999 (PubMed)
    Zeige alle 6 Referenzen für 361726

  5. Human Polyclonal DNMT1 Primary Antibody für EIA, WB - ABIN356564 : Saito, Kanai, Nakagawa, Sakamoto, Saito, Ishii, Hirohashi: Increased protein expression of DNA methyltransferase (DNMT) 1 is significantly correlated with the malignant potential and poor prognosis of human hepatocellular carcinomas. in International journal of cancer. Journal international du cancer 2003 (PubMed)
    Zeige alle 6 Referenzen für 356564

  6. Human Polyclonal DNMT1 Primary Antibody für DB - ABIN389901 : Siedlecki, Garcia Boy, Comagic, Schirrmacher, Wiessler, Zielenkiewicz, Suhai, Lyko: Establishment and functional validation of a structural homology model for human DNA methyltransferase 1. in Biochemical and biophysical research communications 2003 (PubMed)
    Zeige alle 5 Referenzen für 389901

  7. Human Polyclonal DNMT1 Primary Antibody für EIA - ABIN358462 : Liao, Siu, Chan, Wong, Ngan, Chan, Li, Khoo, Cheung: Hypermethylation of RAS effector related genes and DNA methyltransferase 1 expression in endometrial carcinogenesis. in International journal of cancer. Journal international du cancer 2008 (PubMed)
    Zeige alle 2 Referenzen für 358462

  8. Human Polyclonal DNMT1 Primary Antibody für DB - ABIN389917 : Dion, Lin, Hubert, Waterland, Wilson: Dnmt1 deficiency promotes CAG repeat expansion in the mouse germline. in Human molecular genetics 2008 (PubMed)
    Zeige alle 2 Referenzen für 389917

  9. Human Polyclonal DNMT1 Primary Antibody für EIA - ABIN358447 : Yang, Andrade, Labialle, Moussette, Geneau, Sinnett, Belisle, Greenwood, Naumova: Parental effect of DNA (Cytosine-5) methyltransferase 1 on grandparental-origin-dependent transmission ratio distortion in mouse crosses and human families. in Genetics 2008 (PubMed)
    Zeige alle 2 Referenzen für 358447

  10. Human Polyclonal DNMT1 Primary Antibody für IF (p), IHC (p) - ABIN671796 : Khan, Tania, Wei, Mei, Fu, Cheng, Xu, Fu: Thymoquinone inhibits cancer metastasis by downregulating TWIST1 expression to reduce epithelial to mesenchymal transition. in Oncotarget 2015 (PubMed)

Weitere Antikörper gegen DNA (Cytosine-5)-Methyltransferase 1 Interaktionspartner

Zebrafish DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) Interaktionspartner

  1. Dnmt1 stability requires UHRF1 (zeige UHRF1 Antikörper) phosphorylation and that crosstalk between the proteins is essential for the function of these two important epigenetic regulators during gastrulation

  2. Lsh (zeige HELLS Antikörper) Is Essential for Maintaining Global DNA Methylation (zeige HELLS Antikörper) Levels in Amphibia and Fish and Interacts Directly with Dnmt1.

  3. Dnmt1 is required for hematopoietic stem and progenitor cells maintenance via cebpa (zeige CEBPA Antikörper) regulation during definitive hematopoiesis in zebrafish

  4. These data provide the first evidence that Uhrf1 (zeige UHRF1 Antikörper) and Dnmt1 function is required for vertebrate lens development and maintenance.

  5. These results suggest that Dnmt1 activity helps direct histone methylation by Suv39h1 (zeige SUV39H1 Antikörper) and that, together, Dnmt1 and Suv39h1 (zeige SUV39H1 Antikörper) help guide the terminal differentiation of particular tissues.

  6. Data show that in dnmt1 homozygous mutants, reactivation of gfp expression occurs in a reproducible subset of cells, raising the possibility of different sensitivities or alternative silencing mechanisms in discrete cell populations.

  7. Thus, our data suggest that Dnmt1 is dispensable for pancreatic duct or endocrine cell formation, but not for acinar cell survival. In addition, Dnmt1 may influence the differentiation of pancreatic beta cell progenitors.

Human DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) Interaktionspartner

  1. these results indicate that DNMT1 mediates aberrant methylation and silencing of SHP-1 gene in chronic myelogenous leukemia cells

  2. reciprocal regulation between miR (zeige MLXIP Antikörper)-148a/152 and DNMT1 in foam cells

  3. MUC1 (zeige MUC1 Antikörper)-C is of functional importance to induction of DNMT1 and DNMT3b (zeige DNMT3B Antikörper) and, in turn, changes in DNA methylation (zeige HELLS Antikörper) patterns in cancer cells.

  4. This study demonstrates novel regulatory circuits involving miR (zeige MLXIP Antikörper)-148a-3p/ERBB3 (zeige ERBB3 Antikörper)/AKT2 (zeige AKT2 Antikörper)/c-myc (zeige MYC Antikörper) and DNMT1 that controls bladder cancer progression, which may be useful in the development of more effective therapies against bladder cancer.

  5. a novel molecular mechanism by which MBD4 (zeige MBD4 Antikörper) inhibits GITR (zeige TNFRSF18 Antikörper) expression in a DNMT1-dependent manner

  6. a model in which the EZH2 (zeige EZH2 Antikörper)/HOXA11 (zeige HOXA11 Antikörper)-AS/LSD1 (zeige KDM1A Antikörper) complex and HOXA11 (zeige HOXA11 Antikörper)-AS/miR (zeige MLXIP Antikörper)-1297/EZH2 (zeige EZH2 Antikörper) cross-talk serve as critical effectors in gastric cancer tumorigenesis and progression.

  7. Studies indicate that DNA methylation (zeige HELLS Antikörper) is mediated by three DNA (Cytosine-5-)-Methyltransferase (DNMTs): DNMT1 is responsible for the maintenance of methylation patterns after DNA replication whereas DNMT3A (zeige DNMT3A Antikörper) and DNMT3B (zeige DNMT3B Antikörper) carry out de novo methylation, and DNMT inhibitors have showed promising results in clinical trials of prostate cancer.

  8. Our results suggest that epigenetic alteration of histone demethylation regulated by reduction of DNMT1 may control induction of EMT (zeige ITK Antikörper) and the CSC phenotype, which facilitates tumorigenesis in PCa (zeige FLVCR1 Antikörper) cells and has important therapeutic implications in targeting epigenetic regulation.

  9. results indicated that the age and total cholesterol concentrations were independent influential factors of ChREBP (zeige MLXIPL Antikörper) methylation and DNMT1 variants could probably influence LDL-C to further modify ChREBP (zeige MLXIPL Antikörper) DNA methylation (zeige HELLS Antikörper)

  10. DNMT1 overexpression is associated with Breast Cancer.

Pig (Porcine) DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) Interaktionspartner

  1. Dnmt1 was indispensable for oocyte cytoplasmic maturation, providing a novel role for Dnmt1 in the regulation of oocyte maturation.

  2. Data show that the expression levels of the 5 epigenetic modifying genes Dnmt1, Dnmt3a (zeige DNMT3A Antikörper), Hdac1 (zeige HDAC1 Antikörper), Kdm3a (zeige KDM3A Antikörper) and Uhrf1 (zeige UHRF1 Antikörper) were higher in group pig in highland (TH) than in group Yorkshire in highland (YH).

  3. DNMT1o is localized mainly in the nuclei of oocytes and early embryos, whereas DNMT1s is expressed in the ooplasm (zeige NLRP5 Antikörper) cortex of oocytes and cytoplasm of early embryos.

  4. results indicate that loss of Dnmt1 in the maternal nucleus during SCNT significantly contributes to the unfaithful maintenance of methylation imprints in cloned embryos

  5. Oocyte-specific Dnmt1 is cytoplasmic during early development.

  6. Dnmt1 mRNA abundance plays an important role during protein regulation, Dnmt1 enzyme is mainly posttranscriptionally regulated.

Cow (Bovine) DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) Interaktionspartner

  1. DNMT1 silencing significantly decreased the methylation levels of miR (zeige MYLIP Antikörper)-29b promoter, up-regulated miR (zeige MYLIP Antikörper)-29b expression and inhibited bovine viral diarrhea virus replication.

  2. Through down-regulating the expression of DNMT1, miR (zeige MYLIP Antikörper)-152 reduced Global DNA methylation (zeige HELLS Antikörper) and the activity of DNMT to reactivate the lactation signal transduction genes Akt (zeige AKT1 Antikörper) and Ppar gamma (zeige PPARG Antikörper).

  3. More DNMT1 mRNA was detected in the transgenic somatic cell nuclear transfer (SCNT) group than the other three groups. Hsp 70.1 mRNA was detected in the in vitro fertilzation embryos. Mash2 (zeige ASCL2 Antikörper) mRNA was present at highest levels in transgenic SCNT embryos.

  4. Our results indicate an essential role for Dnmt1 during bovine preimplantation development (zeige MTA2 Antikörper), and suggest proper transcriptional reprogramming of this gene family in SCNT embryos.

  5. Dnmt1 is retained in the cytoplasm in metaphase II stage oocytes and zygotes, it enters the nuclei of 8-16 cell stage embryos

  6. Abnormal gene expression of DNMT, INFT, and MHC1 was noted in the majority of cloned embryos, indicating inefficient nuclear reprogramming and retarded embryo development.

  7. Results describe the alternative splicing and expression analysis of bovine DNA methyltransferase 1.

  8. Report inhibition of DNA methyltransferase 1 expression in bovine fibroblast cells used for nuclear transfer.

Arabidopsis thaliana DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) Interaktionspartner

  1. MET1 is a thylakoid-associated TPR protein involved in photosystem II supercomplex formation and repair in Arabidopsis

  2. Met1 gene expression throughout normal development, particularly in the flower

  3. MET1 is a contributor to epigenetic diversity in Arabidopsis.

  4. VIM (zeige VIM Antikörper) proteins regulate genome-wide epigenetic gene silencing through coordinated modulation of DNA methylation (zeige HELLS Antikörper) and histone modification status in collaboration with MET1

  5. VIM (zeige VIM Antikörper) proteins function in transcriptional regulation via their roles in the MET1 DNA methylation (zeige HELLS Antikörper) pathway.

  6. Genetic studies indicate that the Polycomb (zeige CBX2 Antikörper) Repressive Complex 2 (PRC2) but not the DNA METHYLTRANSFERASE1 (MET1) is involved in regulating imprinted expression in the embryo. [MET1]

  7. MET1 restores body methylation, which is region-specific but random with respect to the affected CG sites, and is moderately although not decisively influenced by transcription.

  8. There is a mechanistic link between two major epigenetic pathways involved in histone and DNA methylation (zeige HELLS Antikörper) in plants by physical interaction of MET1 with the FIS-PRC2 core component MEA.

  9. Our results bear interesting similarities with cancer cells, which show global losses of DNA methylation (zeige HELLS Antikörper) but ectopic hypermethylation of genes previously marked by H3K27m3.

  10. An intergenic nucleosome-free crossover hotspot 3a undergoes increased recombination activity in met1.

Mouse (Murine) DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) Interaktionspartner

  1. reciprocal regulation between miR (zeige MLXIP Antikörper)-148a/152 and DNMT1 in foam cells

  2. indispensable role of DNMT1-mediated epigenetic regulation in postnatal liver growth and regeneration

  3. SETDB1 (zeige SETDB1 Antikörper) maintains silencing of intracisternal A particle, but in the absence of DNMT1, prolonged binding of NP95 (zeige UHRF1 Antikörper) to hemimethylated DNA transiently disrupts SETDB1 (zeige SETDB1 Antikörper)-dependent H3K9me3 deposition.

  4. Arx and Dnmt1 that are sufficient for achieving targeted generation of beta cells from adult pancreatic alpha cells.

  5. The results of this study showed that DNA Methyltransferase 1 is main role of Development of the Hippocampal Dentate Gyrus in mice.

  6. three DNA methyltransferases, Dnmt1, Dnmt3a (zeige DNMT3A Antikörper), and Dnmt3b (zeige DNMT3B Antikörper), have been identified. Dnmt3a (zeige DNMT3A Antikörper) and Dnmt3b (zeige DNMT3B Antikörper) are responsible for establishing DNA methylation (zeige HELLS Antikörper) patterns produced through their de novo-type DNA methylation (zeige HELLS Antikörper) activity in implantation stage embryos and during germ cell differentiation. Dnmt3-like (Dnmt3l (zeige TRDMT1 Antikörper)), which is a member of the Dnmt3 family but does not possess DNA methylation (zeige HELLS Antikörper)

  7. While lens epithelial cell survival requires DNMT1, morphologically normal lenses develop in the absence of both DNMT3A (zeige DNMT3A Antikörper) and DNMT3B (zeige DNMT3B Antikörper).

  8. Our results provide insights into the molecular basis of DNMT1 dysfunction in hereditary sensory and autonomic neuropathies with dementia and hearing loss patients and emphasize the importance of the TS domain in the regulation of DNA methylation (zeige HELLS Antikörper) in pluripotent and differentiating cells

  9. miR (zeige MLXIP Antikörper)-29a mimic transfection lowered collagen 1alpha1, DNMT1, DNMT3b (zeige DNMT3B Antikörper) and SET1A (zeige SETD1A Antikörper) expression in hepatic stellate cells.

  10. These results demonstrate that Dnmt1 and Dnmt3b (zeige DNMT3B Antikörper) cooperate to maintain DNA methylation (zeige HELLS Antikörper) and genomic integrity in the intestinal epithelium.

DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) Antigen-Profil

Protein Überblick

DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit DNMT1

  • DNA (cytosine-5-)-methyltransferase 1 (DNMT1) Antikörper
  • DNA (cytosine-5-)-methyltransferase 1 (dnmt1) Antikörper
  • DNA (cytosine-5-)-methyltransferase 1 (Dnmt1) Antikörper
  • DNA (cytosine-5)-methyltransferase 1 (MET1) Antikörper
  • DNA methyltransferase (cytosine-5) 1 (Dnmt1) Antikörper
  • ADCADN Antikörper
  • AIM Antikörper
  • cb983 Antikörper
  • cb1075 Antikörper
  • Cxxc9 Antikörper
  • DDM2 Antikörper
  • DECREASED DNA METHYLATION 2 Antikörper
  • dmnt1 Antikörper
  • DMT01 Antikörper
  • DMT1 Antikörper
  • DNA METHYLTRANSFERASE Antikörper
  • DNA METHYLTRANSFERASE 01 Antikörper
  • DNA METHYLTRANSFERASE 1 Antikörper
  • Dnmt Antikörper
  • Dnmt1o Antikörper
  • fb05h01 Antikörper
  • HSN1E Antikörper
  • m.MmuI Antikörper
  • MCMT Antikörper
  • Met-1 Antikörper
  • Met1 Antikörper
  • MET2 Antikörper
  • methyltransferase 1 Antikörper
  • METHYLTRANSFERASE 2 Antikörper
  • METHYLTRANSFERASE I Antikörper
  • METI Antikörper
  • MommeD2 Antikörper
  • mta Antikörper
  • MTase Antikörper
  • wu:fb05h01 Antikörper

Bezeichner auf Proteinebene für DNMT1

DNA (cytosine-5)-methyltransferase 1 , ddn , CXXC-type zinc finger protein 9 , DNA MTase HsaI , DNA methyltransferase HsaI , m.HsaI , DNA methyltransferase 1 , DNA (cytosine 5 ) methyltransferase 1 , DNA methyltransferase (cytosine 5 ) methyltransferase , DNA methyltransferase b , DNA MTase RnoIP , DNA methyltransferase (cytosine-5) 1 , DNA methyltransferase I , MCMT , m.RnoIP , DNA MTase GgaI , DNA MeTase , DNA methyltransferase GgaI , m.GgaI , DNA MTase MmuI , DNA methyltransferase MmuI

GENE ID SPEZIES
443549 Ovis aries
30430 Danio rerio
1786 Homo sapiens
476715 Canis lupus familiaris
606746 Sus scrofa
281119 Bos taurus
84350 Rattus norvegicus
396011 Gallus gallus
834975 Arabidopsis thaliana
13433 Mus musculus
Ausgewählte Anbieter für anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) Antikörper
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