anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 41 (DDX41) Antikörper

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. Zusätzlich bieten wir Ihnen DDX41 Kits (10) und DDX41 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
DDX41 51428 Q9UJV9
DDX41 72935 Q91VN6
DDX41 314336  
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Top anti-DDX41 Antikörper auf antikoerper-online.de

Showing 10 out of 72 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-DDX41 Antibody Titration: </b>1.25ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Jurkat cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Human Maus Unkonjugiert IF, WB Immunofluorescence of monoclonal antibody to DDX41 on HeLa cell (antibody concentration 10 µg/mL). Western Blot analysis of DDX41 expression in transfected 293T cell line by DDX41 monoclonal antibody (M01), clone 2F4. Lane 1: DDX41 transfected lysate(70 KDa). Lane 2: Non-transfected lysate. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$450.00
Details
Human Kaninchen Unkonjugiert WB DDX41 Antibody (N-term) (ABIN1881255) western blot analysis in T47D cell line lysates (35 µg/lane). This demonstrates the DDX41 antibody detected the DDX41 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Fledermaus Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$493.17
Details
Human Kaninchen Unkonjugiert IP, WB Western Blot and Immunoprecipitation: DDX4 Antibody [ABIN252826] - Detection of Human DDX41 by Western Blot and Immunoprecipitation. Samples: Whole cell lysate (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded) from HeLa cells. Antibody: Affinity purified rabbit anti-DDX41 antibody ABIN252826 used for WB at 1 mcg/ml (A and B) and used for IP at 3 mcg/mg lysate.  Detection: Chemiluminescence with exposure times of 30 seconds (A) and 3 minutes (B). Western Blot: DDX41 Antibody  - Detection of Human and Mouse DDX41 by Western Blot. Samples: Whole cell lysate from HeLa (50, 15 ug) and mouse NIH3T3 (50 ug) cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-DDX41 antibody  used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes. 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$556.31
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert WB WB Image Sample (30 ug of whole cell lysate) A: H1299 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Rind (Kuh) Ziege Unkonjugiert ELISA, WB ABIN4902607 (0.5µg/ml) staining of Bone Marrow lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μL Anmelden zum Anzeigen 16 Days
$444.57
Details
Hund Kaninchen Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$446.88
Details

DDX41 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Mouse (Murine)
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Rat (Rattus)
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Am meisten referenzierte anti-DDX41 Antikörper

  1. Human Polyclonal DDX41 Primary Antibody für WB - ABIN1881255 : Wu, Ma, Brown, Geisler, Li, Tzeng, Jia, Jurisica, Li: Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening. in Proteomics 2007 (PubMed)
    Show all 3 Pubmed References

  2. Cow (Bovine) Polyclonal DDX41 Primary Antibody für WB - ABIN2775230 : Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in Molecular systems biology 2007 (PubMed)

  3. Human Monoclonal DDX41 Primary Antibody für IF, ELISA - ABIN565608 : Omura, Oikawa, Nakane, Kato, Ishii, Ishitani, Tokunaga, Nureki: Structural and Functional Analysis of DDX41: a bispecific immune receptor for DNA and cyclic dinucleotide. in Scientific reports 2016 (PubMed)

Weitere Antikörper gegen DDX41 Interaktionspartner

Human DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 41 (DDX41) Interaktionspartner

  1. DDX41 mutations lead to development of high-risk myelodysplastic syndrome.(review)

  2. An increasing number of both inherited and acquired mutations in DDX41 gene are identified from myelodysplastic syndrome and/or acute myeloid leukemia (zeige BCL11A Antikörper) (MDS (zeige PAFAH1B1 Antikörper)/AML (zeige RUNX1 Antikörper)) patients.

  3. data demonstrate that DDX41 suppresses p21 (zeige CDKN1A Antikörper) translation without disturbing the function of p53 (zeige TP53 Antikörper) to directly induce p21 (zeige CDKN1A Antikörper) mRNA expression, this process indirectly requires p53 (zeige TP53 Antikörper), perhaps in the form of another p53 (zeige TP53 Antikörper) target gene or as a still undefined posttranscriptional function of p53 (zeige TP53 Antikörper).

  4. This study uncovered a pathogenic role of p.R525H DDX41 in the slow growth rate of tumor cells. Age-dependent epigenetic alterations or other somatic changes might collaborate with the mutation to cause AML (zeige RUNX1 Antikörper).

  5. This study expands both the mutation and phenotypic spectra observed in families with germ line DDX41 mutations.

  6. corresponding deletions on 5q35.3 present in 6% of cases led to haploinsufficient DDX41 expression. DDX41 lesions caused altered pre-mRNA splicing and RNA processing

  7. results suggest a mechanism whereby c-di-GMP (zeige NT5C2 Antikörper) and c-di-AMP (zeige APRT Antikörper) are detected by DDX41, which forms a complex with STING to signal to TBK1 (zeige TBK1 Antikörper)-IRF3 (zeige IRF3 Antikörper) and activate the interferon (zeige IFNA Antikörper) response

  8. DDX41 is an additional DNA sensor that depends on STING to sense pathogenic DNA.

  9. The N-terminal domain of Abs interacts with the phox homology (PX) domain of SNX2 (zeige SNX2 Antikörper) suggesting that PX domains may also participate in protein-protein interaction.

Mouse (Murine) DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 41 (DDX41) Interaktionspartner

  1. Tyr364 and Tyr414 of DDX41 are critical for its recognition of AT-rich DNA and binding to STING, and tandem mass spectrometry identifies Tyr414 as the BTK (zeige BTK Antikörper) phosphorylation site.

  2. TRIM21 (zeige TRIM21 Antikörper) is an interferon (zeige IFNA Antikörper)-inducible E3 ligase that induces the Lys48-linked ubiquitination and degradation of DDX41 and negatively regulates the innate immune response to intracellular double-stranded DNA.

  3. DDX41 is an additional DNA sensor that depends on STING to sense pathogenic DNA.

DDX41 Antigen-Profil

Protein Überblick

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The function of this member has not been determined. Based on studies in Drosophila, the abstrakt gene is widely required during post-transcriptional gene expression.

Genbezeichner und Symbole assoziert mit DDX41

  • DEAD-box helicase 41 (DDX41) Antikörper
  • probable ATP-dependent RNA helicase DDX41 (LOC100215941) Antikörper
  • DEAD-box helicase 41 (ddx41) Antikörper
  • probable ATP-dependent RNA helicase DDX41 (LOC100638079) Antikörper
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 (Ddx41) Antikörper
  • DEAD-box helicase 41 (Ddx41) Antikörper
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 (ddx41) Antikörper
  • 2900024F02Rik Antikörper
  • AA958953 Antikörper
  • ABS Antikörper
  • AI324246 Antikörper
  • DDX41 Antikörper
  • wu:fb92e02 Antikörper
  • zgc:55896 Antikörper

Bezeichner auf Proteinebene für DDX41

DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 , DEAD-box protein abstrakt , probable ATP-dependent RNA helicase DDX41-like , 2900024F02Rik , DEAD box protein 41 , DEAD box protein abstrakt homolog , probable ATP-dependent RNA helicase DDX41 , putative RNA helicase

GENE ID SPEZIES
427630 Gallus gallus
462310 Pan troglodytes
700742 Macaca mulatta
100031917 Monodelphis domestica
100058316 Equus caballus
100215941 Hydra magnipapillata
100401323 Callithrix jacchus
100437507 Pongo abelii
100474236 Ailuropoda melanoleuca
100491281 Xenopus (Silurana) tropicalis
100550300 Meleagris gallopavo
100554935 Anolis carolinensis
100638079 Amphimedon queenslandica
51428 Homo sapiens
479274 Canis lupus familiaris
505276 Bos taurus
72935 Mus musculus
314336 Rattus norvegicus
394020 Danio rerio
101102307 Ovis aries
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