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D-dopachrome tautomerase converts D-dopachrome into 5,6-dihydroxyindole. Zusätzlich bieten wir Ihnen D-Dopachrome Tautomerase Antikörper (77) und D-Dopachrome Tautomerase Proteine (16) und viele weitere Produktgruppen zu diesem Protein an.
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These results have implications for the manner in which D-DT and MIF (zeige AMH ELISA Kits) compete with each other for binding to the CD74 (zeige CD74 ELISA Kits) receptor and for the relative potency of DRa1-MOG-35-55 and RTL1000 for competitive inhibition of D-DT and MIF (zeige AMH ELISA Kits) binding and activation through CD74 (zeige CD74 ELISA Kits).
Study demonstrated that DDT was over- expressed in pancreatic ductal adenocarcinoma (PDAC) tissues and cell lines in a pattern correlated with MIF (zeige AMH ELISA Kits), and knockdown of DDT and MIF (zeige AMH ELISA Kits) in PANC- 1 cells cooperatively inhibited cell proliferation, invasion and tumor formation. The tautomerase activities of both MIF (zeige AMH ELISA Kits) and DDT are required for their negative regulatory role in p53 (zeige TP53 ELISA Kits) and their tumor-promoting functions.
DDT was increased in burn patients.
Gene expression level of DDT is significantly higher in AD patients when compared to normal controls.
High MIF-2 (zeige CENPC1 ELISA Kits) levels are predictive of the development of organ dysfunction in myocardial ischemia reperfusion injury.
Both p53 (zeige TP53 ELISA Kits) wildtype and mutant human lung adenocarcinoma tumors rely on MIF (zeige AMH ELISA Kits) family members for maximal cell growth and survival.
findings identify DDT as a functionally redundant but more potent cytokine to MIF (zeige AMH ELISA Kits) in cancer and suggest that current attempts to inhibit MIF (zeige AMH ELISA Kits) signaling may fail because of DDT compensation.
D-dopachrome tautomerase secreted from adipocytes acts on preadipocytes to promote IL-6 (zeige IL6 ELISA Kits) expression and to inhibit adipogenesis by suppressing the induction of genes encoding adipogenic regulators
DDT acts on adipocytes to regulate lipid metabolism through AMPK (zeige PRKAA1 ELISA Kits) and/or PKA pathway(s) and improves glucose intolerance caused by obesity.
These data indicate that D-DT is a MIF (zeige AMH ELISA Kits)-like cytokine.
cardiomyocyte secretion of DDT has important autocrine/paracrine effects during ischemia-reperfusion that protect the heart against injury
These data point to a potential involvement of D-dopachrome tautomerase activity in the mature mouse brain, and suggest some functional and evolutionary relationship between innate immunity and tautomerization of D-dopachrome in mammalian species
These data indicate that D-DT is a MIF (zeige MIF ELISA Kits)-like cytokine.
D-dopachrome tautomerase converts D-dopachrome into 5,6-dihydroxyindole. The DDT gene is related to the migration inhibitory factor (MIF) in terms of sequence, enzyme activity, and gene structure. DDT and MIF are closely linked on chromosome 22.
, D-dopachrome decarboxylase-A
, D-dopachrome tautomerase-A
, D-dopachrome decarboxylase-B
, D-dopachrome tautomerase-B
, D-dopachrome tautomerase
, dopachrome isomerase
, phenylpyruvate tautomerase II