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The protein encoded by CRLF2 is a receptor for thymic stromal lymphopoietin (TSLP). Zusätzlich bieten wir Ihnen CRLF2 Proteine (15) und CRLF2 Kits (7) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 115 products:
Human Monoclonal CRLF2 Primary Antibody für FACS, IHC - ABIN2661304
Wang, Ito, Wang, Homey, Watanabe, Martin, Barnes, McIntyre, Gilliet, Kumar, Yao, Liu: Maintenance and polarization of human TH2 central memory T cells by thymic stromal lymphopoietin-activated dendritic cells. in Immunity 2006
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Human Monoclonal CRLF2 Primary Antibody für FACS, WB - ABIN4899885
Shan, Redhu, Saleh, Halayko, Chakir, Gounni: Thymic stromal lymphopoietin receptor-mediated IL-6 and CC/CXC chemokines expression in human airway smooth muscle cells: role of MAPKs (ERK1/2, p38, and JNK) and STAT3 pathways. in Journal of immunology (Baltimore, Md. : 1950) 2010
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Mouse (Murine) Polyclonal CRLF2 Primary Antibody für FACS - ABIN4896188
Oh, Oh, Yu, Myers, Leonard, Liu, Zhu, Zheng: IL-13 induces skin fibrosis in atopic dermatitis by thymic stromal lymphopoietin. in Journal of immunology (Baltimore, Md. : 1950) 2011
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Mouse (Murine) Polyclonal CRLF2 Primary Antibody für FACS, Neut - ABIN4899486
Osborn, Ryan, Kirchhof, Panoskaltsis-Mortari, Mortari, Tudor: Overexpression of murine TSLP impairs lymphopoiesis and myelopoiesis. in Blood 2004
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Human Polyclonal CRLF2 Primary Antibody für IHC (p), WB - ABIN318884
Park, Martin, Garka, Gliniak, Di Santo, Muller, Largaespada, Copeland, Jenkins, Farr, Ziegler, Morrissey, Paxton, Sims: Cloning of the murine thymic stromal lymphopoietin (TSLP) receptor: Formation of a functional heteromeric complex requires interleukin 7 receptor. in The Journal of experimental medicine 2000
CRLF2 overexpression is associated with childhood B-cell acute lymphoblastic leukemia.
CRLF2 gene rearrangement is associated with acute lymphoblastic leukemia.
TSLPR levels were found to be significantly higher in asthmatic than in nonasthmatic children. TSLPR expression in non-allergic asthmatic and allergic asthmatic groups was found to be significantly higher than in non-allergic nonasthmatic group
In adult B-cell acute lymphoblastic leukemia without recurrent fusion genes , high CRLF2 expression is associated with distinct clinico-biological features and an unfavourable prognosis
CD4 (zeige CD4 Antikörper)+ T cells from atopic dermatitis patients directly interacted with TSLP (zeige TSLP Antikörper) to produce a higher amount of IL-4 (zeige IL4 Antikörper) than those from normal subjects, and this action was attenuated with anti-TSLPR antibody
The levels of mRNA for TSLP (zeige TSLP Antikörper) and TSLPR were significantly elevated in parotid gland tissues from the KD group as compared to the control group.
Differences exist in the genetic profiles of Down syndrome-associated acute lymphoblastic leukemia patients in Japan and in Western countries, and that P2RY8 (zeige P2RY8 Antikörper)-CRLF2 and EBF1 (zeige EBF1 Antikörper) deletions may cooperate in leukemogenesis in a subset of Japanese DS-ALL patients.
CRLF2 overexpression (OE) was detected in 30 (18%) of 167 patients, the P2RY8-CRLF2 fusion was identified in only 3 (1.8%) of 167 patients, all of which demonstrated CRLF2 OE.
we report noncysteine in-frame mutations in IL7R (zeige IL7R Antikörper) and CRLF2 located in a region of the transmembrane domain closer to the cytosolic domain in acute lymphoblastic leukemias
The TSLPR in blood plateltes promotes platelet activation via activating the PI3K (zeige PIK3CA Antikörper)/AKT (zeige AKT1 Antikörper) pathway.
A novel mouse xenograft model to study the role of TSLP (zeige TSLP Antikörper)-induced CRLF2 (zeige CRLF3 Antikörper) signals in normal and malignant human B lymphopoiesis has been developed.
High-cholesterol diet increased TSLPR expression and atherosclerosis. High-dose ticagrelor moderated this trend. It modulated platelet activity and atherosclerosis mediated by TSLPR, potentially through the PI3K/Akt (zeige AKT1 Antikörper) signal pathway.
Activating thymic stromal lymphopoietin (zeige TSLP Antikörper) promotes atherosclerosis by inducing Th17/Treg imbalance through TSLPR signaling in a mouse model.
Suggest that Treg defects in ApoE (zeige APOE Antikörper)(-/-) mice might partially be attributed to the disruption of TSLP (zeige TSLP Antikörper)-TSLPR-LAP signaling in epithelial cells and dendritic cells.
The structure of the mouse TSLP (zeige TSLP Antikörper)-mediated signaling complex reveals how TSLP (zeige TSLP Antikörper) establishes extensive interfaces with its cognate receptor (TSLPR).
TSLPR helps to create a permissive microenvironment for the development and pulmonary metastasis of mammary carcinoma in a mouse model using implanted 4T1 tumour cells.
A previously unrecognized role was found for TSLP (zeige TSLP Antikörper)/TSLPR signaling in type 2 immunity as an important enhancer for the development of alternately activated macrophages as well as for chemokine (zeige CCL1 Antikörper) production.
mice deficient in TSLP receptors on LCs abrogated the induction of OVA-specific IgE levels upon epicutaneous OVA sensitization.
Increased susceptibility to autoimmune gastritis in thymic stromal lymphopoietin receptor-deficient mice.
Presence of functional TSLP (zeige TSLP Antikörper)-specific receptor chain is required for the development of T helper cell type (Th)2 contact hypersensitivity to the hapten fluorescein isothiocyanate (FITC).
The protein encoded by this gene is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Two transcript variants encoding different isoforms have been found for this gene.
cytokine receptor-like factor 2
, P2RY8/CRLF2 fusion
, TSLP receptor
, cytokine receptor CRL2 precusor
, cytokine receptor-like 2
, thymic stromal lymphopoietin protein receptor
, thymic stromal lymphopoietin receptor
, thymic stromal-derived lymphopoietin receptor
, cytokine receptor-like molecule 2
, delta 1
, lymphocyte antigen 114
, thymic stromal-derived lymphopoietin, receptor
, transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
, type I cytokine receptor delta 1