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The protein encoded by KRT1 is a member of the keratin gene family. Zusätzlich bieten wir Ihnen KRT1 Kits (18) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 107 products:
Human Polyclonal KRT1 Primary Antibody für IHC, IHC (p) - ABIN4303928
Ambatipudi, Bhosale, Heath, Pandey, Kumar, Kane, Patil, Maru, Desai, Watt, Mahimkar: Downregulation of keratin 76 expression during oral carcinogenesis of human, hamster and mouse. in PLoS ONE 2013
Show all 2 Pubmed References
Chicken Monoclonal KRT1 Primary Antibody für ELISA, FACS - ABIN4303932
Franchini, Ottaviani: Immunoreactive POMC-derived peptides and cytokines in the chicken thymus and bursa of Fabricius microenvironments: age-related changes. in Journal of neuroendocrinology 1999
Human Polyclonal KRT1 Primary Antibody für ICC, IF - ABIN4303929
DiTommaso, Cottle, Pearson, Schlüter, Kaur, Humbert, Smyth: Keratin 76 is required for tight junction function and maintenance of the skin barrier. in PLoS genetics 2014
KRT1 and the specific polymorphism of KRT1 in this Chinese Han population are associated with autoimmune diseases SLE and SSc (zeige CYP11A1 Antikörper)
Case Report: post-zygotic mosaicism of KRT/1o mutations in epidermolytic Ichthyosis (zeige LBR Antikörper).
KRT1 played an important role of maintaining epithelial barrier and its down-regulation in intestinal tissue was correlated with the progression of inflammatory bowel disease.
Report genetic/clinical spectrum of KRT1 mutations in keratinopathic ichthyosis (zeige LBR Antikörper).
demonstrated the presence of a genetic cutaneous mosaicism. Both patients carry the KRT1 pI479T substitution, but in the palmoplantar areas of one of them, only the mutated allele is expressed (hemizygous). This leads to highlight a new type of cutaneous mosaic, the palmoplantar mosaicism
In our study, the missense mutation in the proband and his mother with epidermolytic ichthyosis (zeige LBR Antikörper) was a single amino acid difference in codon 478, which causes more serious skin manifestations
Complete structure of an epithelial keratin 1/keratin 10 (zeige KRT10 Antikörper) dimer has been presented.
These findings indicate that exogenous FABP4 (zeige FABP4 Antikörper) interacts with plasma membrane proteins, specifically CK1 (zeige CSNK1A1L Antikörper).
analysis of a heterozygous novel splice junction mutation in the 2B domain of KRT1 in a family with diffuse palmoplantar keratoderma
In ichthyosis (zeige LBR Antikörper) with confetti, a causal de novo KRT1 mutation had a C-terminal frameshift, replacing 22 C-terminal AAs (zeige FGD1 Antikörper) with an alternate 30-AA peptide. It distorted the IF network and mislocalized to the nucleus. Reversion occurred by mitotic recombination.
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
67 kDa cytokeratin
, cytokeratin 1
, epidermolytic hyperkeratosis 1
, hair alpha protein
, keratin, type II cytoskeletal 1
, type-II keratin Kb1