anti-Cytohesin 2 (CYTH2) Antikörper

The protein encoded by CYTH2 is a member of the PSCD family. Zusätzlich bieten wir Ihnen Cytohesin 2 Proteine (10) und Cytohesin 2 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CYTH2 9266 Q99418
CYTH2 116692 P63035
CYTH2 19158 P63034
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Top anti-Cytohesin 2 Antikörper auf antikoerper-online.de

Showing 10 out of 87 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of PSCD2 Antibody (N-term) in mouse kidney tissue lysates (35ug/lane). This demonstrates the PSCD2 antibody detected the PSCD2 protein (arrow). 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Ziege Unkonjugiert ELISA, WB ABIN238611 (0.5µg/ml) staining of Human Brain (Cerebellum) lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 3 bis 4 Tage
349,82 €
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Rind (Kuh) Ziege Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
722,86 €
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Maus Kaninchen Unkonjugiert WB PSCD2 Antibody (N-term) (ABIN656173) western blot analysis in mouse kidney tissue lysates (35 µg/lane). This demonstrates the PSCD2 antibody detected the PSCD2 protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
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Hund Ziege Unkonjugiert WB   0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
357,50 €
Details
Human Maus Unkonjugiert IF, IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to CYTH2 on formalin-fixed paraffin-embedded human colon. [antibody concentration 3 ug/ml] Immunofluorescence of monoclonal antibody to CYTH2 on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Anmelden zum Anzeigen 7 bis 8 Tage
369,60 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB   100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
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Human Maus Unkonjugiert ICC, IF, ELISA, WB 0.05 mL Anmelden zum Anzeigen 2 bis 4 Tage
291,00 €
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Human Ziege Unkonjugiert ELISA, WB 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
505,48 €
Details
Human Maus Unkonjugiert FACS, ICC, IF, IHC, IHC (p), IP Immunocytochemistry/Immunofluorescence: Cytohesin 2 Antibody (10A12) [NBP2-22514] - Analysis of Cytohesin 2 in HepG2 Cells. Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with a Cytohesin 2 monoclonal antibody at a dilution of 1:100 overnight at 4C, washed with PBS and incubated with a DyLight-488 conjugated secondary antibody. Cytohesin 2 staining (green), F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue) is shown. Immunocytochemistry/Immunofluorescence: Cytohesin 2 Antibody (10A12) [NBP2-22514] - Analysis of Cytohesin 2 in HeLa Cells. Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with a Cytohesin 2 monoclonal antibody at a dilution of 1:100 overnight at 4C, washed with PBS and incubated with a DyLight-488 conjugated secondary antibody. Cytohesin 2 staining (green), F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue) is shown. 0.1 mg Anmelden zum Anzeigen 3 bis 6 Tage
311,00 €
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CYTH2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Cytohesin 2 Antikörper

  1. Human Polyclonal Cytohesin 2 Primary Antibody für ELISA, WB - ABIN262292 : Kolanus: Guanine nucleotide exchange factors of the cytohesin family and their roles in signal transduction. in Immunological reviews 2007 (PubMed)

  2. Human Monoclonal Cytohesin 2 Primary Antibody für IF, IHC (p) - ABIN564002 : Mannell, Pircher, Chaudhry, Alig, Koch, Mettler, Pohl, Krötz: ARNO regulates VEGF-dependent tissue responses by stabilizing endothelial VEGFR-2 surface expression. in Cardiovascular research 2011 (PubMed)

Weitere Antikörper gegen Cytohesin 2 Interaktionspartner

Human Cytohesin 2 (CYTH2) Interaktionspartner

  1. ARNO-ARF1 regulates formation of podosomes by inhibition of RhoA/myosin-II and promotion of actin core assembly.

  2. Authors' experiments argue against ARNO being a robust modifier of EGFR (zeige EGFR Antikörper) catalytic activity.

  3. Data establish a role for cytohesin-2/ARNO as a regulator of R-Ras and integrin recycling and suggest that ARF (zeige CDKN2A Antikörper)-regulated trafficking of R-Ras is required for R-Ras-dependent effects on spreading and adhesion formation.

  4. The authors show that Shigella flexneri IpgD phosphatase activity is required for recruitment of the ARF6 (zeige ARF6 Antikörper) guanine nucleotide exchange factor (zeige RASGRF1 Antikörper) (GEF (zeige SLC2A4RG Antikörper)) ARF nucleotide binding site opener (ARNO) to bacterial entry sites.

  5. inhibiting cytohesins or ARNO as cytoplasmic activators of EGFR (zeige EGFR Antikörper) and IGF-I (zeige IGF1 Antikörper) in colorectal cancer resulted in anti-proliferation, reduced invasion, decreased migration, and suppressed growth in vivo and in vitro.

  6. Cytohesin-2 constitutively suppresses platelet dense granule secretion and aggregation by keeping ARF6 (zeige ARF6 Antikörper) in a GTP (zeige AK3 Antikörper)-bound state

  7. Expression of CYTH2 mutant deficient of the EFh2 domain in cells also inhibits Arf6 (zeige ARF6 Antikörper) activation and neurite extension.

  8. Phosphorylation of Ser392 of ARNO stabilized the C-terminal alpha-helix via formation of salt bridges between phospho-Ser392 and Arg390, Lys395, and Lys396.

  9. There is an association between cytohesin-2 expression and overall survival and disease-free survival in patients with hepatocellular carcinoma.

  10. Arf6 (zeige ARF6 Antikörper)/ ARNO signaling mediates phospholipase-D (zeige PLD Antikörper), ERK1/2 (zeige MAPK1/3 Antikörper) and cofilin (zeige CFL1 Antikörper) activation in pancreatic beta-cells.

Mouse (Murine) Cytohesin 2 (CYTH2) Interaktionspartner

  1. results show that ARNO interaction with the RLIP76 (zeige RALBP1 Antikörper) N-terminus regulates cell spreading and motility via PI3K and Arf6 (zeige ARF6 Antikörper), independent of RLIP76 (zeige RALBP1 Antikörper) control of Rac (zeige AKT1 Antikörper)

  2. The RLIP76 (zeige RALBP1 Antikörper)/R-Ras/ARNO complex localizes to recycling endosomes.

  3. signaling through cytohesin-2 is required for myelination by Schwann cells, and cytohesin-2 is added to the list of molecules known to underlie PNS myelination

  4. results together suggest that cytohesin 2 activates ARF6 (zeige ARF6 Antikörper) in a PI3K dependent manner and then the active ARF6 (zeige ARF6 Antikörper) causes phosphorylation of ERK1/2 (zeige MAPK1/3 Antikörper) during preadipocyte migration.

  5. Cytohesin-2 constitutively suppresses platelet dense granule secretion and aggregation by keeping ARF6 (zeige ARF6 Antikörper) in a GTP (zeige AK3 Antikörper)-bound state

  6. Expression of CYTH2 mutant deficient of the EFh2 domain in cells also inhibits Arf6 (zeige ARF6 Antikörper) activation and neurite extension.

  7. The N termini of a-subunit isoforms are involved in signaling between vacuolar H+-ATPase (zeige ATP6V1B2 Antikörper) (V-ATPase (zeige DNAH8 Antikörper)) and cytohesin-2

  8. role for endothelial ARNO in VEGF (zeige VEGFA Antikörper)-dependent initiation of angiogenesis by regulation of VEGFR-2 (zeige KDR Antikörper) internalization in endothelial cells, resulting in the activation of the Akt (zeige AKT1 Antikörper) pathway, vessel permeability, and ultimately endothelial proliferation

  9. cytohesin-2, through a previously unexplored complex formation with paxillin (zeige PXN Antikörper), regulates preadipocyte migration; paxillin (zeige PXN Antikörper) plays a previously unknown role as a scaffold protein (zeige HOMER1 Antikörper) of Arf (zeige CDKN2A Antikörper) guanine-nucleotide exchange factor (zeige ARHGEF12 Antikörper)

  10. Specific motifs of the V-ATPase a2 (zeige ATP6V0A2 Antikörper)-subunit isoform interact with catalytic and regulatory domains of ARNO.

Cytohesin 2 (CYTH2) Antigen-Profil

Protein Überblick

The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with ARF1, ARF3, and ARF6 and is 83% homologous to CYTH1. Two transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit anti-Cytohesin 2 (CYTH2) Antikörper

  • cytohesin-2 (PTRG_08834) Antikörper
  • cytohesin 2 (cyth2) Antikörper
  • cytohesin 2 (CYTH2) Antikörper
  • pleckstrin homology, Sec7 and coiled-coil domains 2 (pscd2) Antikörper
  • cytohesin 2 (Cyth2) Antikörper
  • Arno Antikörper
  • CLM2 Antikörper
  • CTS18 Antikörper
  • CTS18.1 Antikörper
  • CYTH2 Antikörper
  • MGC80440 Antikörper
  • MGC84366 Antikörper
  • Pscd2 Antikörper
  • PSCD2L Antikörper
  • Sec7 Antikörper
  • Sec7B Antikörper
  • SEC7L Antikörper
  • Sec7p-L Antikörper
  • Sec7p-like Antikörper

Bezeichner auf Proteinebene für anti-Cytohesin 2 (CYTH2) Antikörper

cytohesin-2 , cytohesin 2 , pleckstrin homology, Sec7 and coiled/coil domains 2 , pleckstrin homology, Sec7 and coiled-coil domains 2 (cytohesin-2) , cytohesin-2-like , ARF exchange factor , ARF nucleotide-binding site opener , PH, SEC7 and coiled-coil domain-containing protein 2 , pleckstrin homology, Sec7 and coiled/coil domains 2 (cytohesin-2) , ARF nucleotide binding site opener , CLM2 , SEC7 homolog B , pleckstrin homology, Sec7 and coiled-coil domains 2 , mSec7-2

GENE ID SPEZIES
6347120 Pyrenophora tritici-repentis Pt-1C-BFP
444689 Xenopus laevis
448569 Xenopus (Silurana) tropicalis
718682 Macaca mulatta
746757 Pan troglodytes
779436 Xenopus laevis
100216436 Ovis aries
100387102 Callithrix jacchus
100440057 Pongo abelii
9266 Homo sapiens
116692 Rattus norvegicus
19158 Mus musculus
476423 Canis lupus familiaris
768035 Bos taurus
100240721 Sus scrofa
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