Cytochrome P450, Family 4, Subfamily B, Polypeptide 1 Proteine (CYP4B1)

CYP4B1 encodes a member of the cytochrome P450 superfamily of enzymes. Zusätzlich bieten wir Ihnen Cytochrome P450, Family 4, Subfamily B, Polypeptide 1 Antikörper (40) und Cytochrome P450, Family 4, Subfamily B, Polypeptide 1 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
CYP4B1 1580 P13584
CYP4B1 13120 Q64462
CYP4B1 24307 P15129
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Showing 5 out of 5 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
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HOST_Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 7 bis 8 Tage
235,20 €
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
3.284,29 €
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CYP4B1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Rat (Rattus)

Weitere Proteine zu Cytochrome P450, Family 4, Subfamily B, Polypeptide 1 (CYP4B1) Interaktionspartnern

Rabbit Cytochrome P450, Family 4, Subfamily B, Polypeptide 1 (CYP4B1) Interaktionspartner

  1. P450 (zeige POR Proteine) 4B1 exhibits structural adaptations for omega-hydroxylation that include changes in the conformation of the heme and changes in a highly conserved helix I motif that is associated with selective oxygenation of unactivated primary C-H bonds.

  2. A co-crystal structure of the rabbit family 4 enzyme CYP4B1 with its substrate octane reveals that the propensity for omega-hydroxylation is orchestrated by active-site sterics, partially mediated by an unusual heme-polypeptide ester bond.

  3. spectral binding affinities and oxidative metabolism of the furan analogs by the purified recombinant CYP4B1 variants were analyzed: the naturally occurring perilla ketone was found to be the tightest binder to CYP4B1, but also the analog that was most extensively metabolized by oxidative processes to numerous non-reactive reaction products.

  4. A proline residue in the meander region at position 427 in human CYP4B1 and 422 in rabbit CYP4B1 is important for protein stability and rescues the 4-ipomeanol bioactivation.

  5. results strongly implicate the corneal CYP4B1 as a component of the inflammatory and neovascular cascade initiated by injury and further suggest that CYP4B1-12-HETrE is a proximal regulator of VEGF expression

Human Cytochrome P450, Family 4, Subfamily B, Polypeptide 1 (CYP4B1) Interaktionspartner

  1. the Ser207 insertion does not rescue the P450 (zeige CYP2B6 Proteine) functional activity of human CYP4B1 that has been lost during evolution.

  2. Single nucleotide polymorphisms of CYP2C8,CYP2E1 and CYP4B1 are associated with susceptibility to gout in ethnic Han males population.

  3. A proline residue in the meander region at position 427 in human CYP4B1 and 422 in rabbit CYP4B1 is important for protein stability and rescues the 4-ipomeanol bioactivation.

  4. CYP4B1 is a senescene-associated gene in normal human oral keratinocytes.

  5. Results demostrated an increased risk of bladder cancer associated with the CYP4B1*1/*2 and *2/*2 genotypes.

  6. Detected by polymerase chain reaction in prostate tissue.

Mouse (Murine) Cytochrome P450, Family 4, Subfamily B, Polypeptide 1 (CYP4B1) Interaktionspartner

  1. Data show that the 5' flanking region of the Cyp4b1 gene exhibits promoter activity when expressed in different cell lines and that a 98-truncated fragment represents the minimal sequence required for basal transcription.

  2. Increased CYP4B1 mRNA is associated with the inhibition of dextran sulfate sodium-induced colitis by caffeic acid in mice.

Cytochrome P450, Family 4, Subfamily B, Polypeptide 1 (CYP4B1) Protein Überblick

Protein Überblick

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens\; however, the specific function of the human protein has not been determined. Two transcript variants encoding slightly different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit CYP4B1

  • cytochrome P450, family 4, subfamily B, polypeptide 1 (CYP4B1)
  • cytochrome P450, family 4, subfamily B, polypeptide 1 (cyp4b1.2)
  • cytochrome P450, family 4, subfamily B, polypeptide 1 (cyp4b1)
  • CYP4B1-like isozyme short form (CYP4B1)
  • cytochrome P450, family 4, subfamily b, polypeptide 1 (Cyp4b1)
  • cyp4b1 Protein
  • CYPIVB1 Protein
  • P-450HP Protein

Bezeichner auf Proteinebene für CYP4B1

cytochrome P450, family 4, subfamily B, polypeptide 1 , cytochrome P450 XL-304 , CYP4B1 isoform , CYPIVB1 , P450-isozyme 5 , cytochrome P450 4B1 , cytochrome P450 isozyme 5 , cytochrome P450, subfamily IVB, polypeptide 1 , cytochrome P450-HP , microsomal monooxygenase , cytochrome P450, subfamily IV B, polypeptide 1 , P450 L-2 , cytochrome P450 L-2 , cytochrome P450, subfamily 4B, polypeptide 1

GENE ID SPEZIES
424618 Gallus gallus
550102 Xenopus (Silurana) tropicalis
100036772 Xenopus laevis
100145080 Xenopus (Silurana) tropicalis
100036771 Xenopus laevis
100008805 Oryctolagus cuniculus
1580 Homo sapiens
540149 Bos taurus
13120 Mus musculus
24307 Rattus norvegicus
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