Cytochrome P450, Family 2, Subfamily J, Polypeptide 2 Proteine (CYP2J2)

CYP2J2 encodes a member of the cytochrome P450 superfamily of enzymes. Zusätzlich bieten wir Ihnen CYP2J2 Antikörper (68) und CYP2J2 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Ratte CYP2J2 CYP2J2 502969  
CYP2J2 1573 P51589
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
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CYP2J2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
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Weitere Proteine zu Cytochrome P450, Family 2, Subfamily J, Polypeptide 2 (CYP2J2) Interaktionspartnern

Human Cytochrome P450, Family 2, Subfamily J, Polypeptide 2 (CYP2J2) Interaktionspartner

  1. CYP2J2 is widely expressed in tissues, especially heart, vascular smooth muscle, salivary glands and placenta. Recent studies have shown that overexpression of CYP2J2 in vivo reverses several pathological processes in animals, including hypertension and other cardiovascular pathologies and insulin (zeige INS Proteine) resistance.

  2. Homocysteine (Hcy) facilitated cytochrome P-450 CYP2J2 (CYP2J2) upregulation in hepatocellular carcinoma (HCC (zeige FAM126A Proteine)) cells by DNA demethylation.

  3. Endothelial overexpression of CYP2J2 significantly changed oxylipin profiles.

  4. MAPK (zeige MAPK1 Proteine) signaling pathway was involved in the up-regulation of CYP2J2 levels by glutamate (zeige GRIN1 Proteine) in U251 cells.

  5. Data show that CYP2J2 gene delivery reduced vessel wall thickening.

  6. Data suggest that antiarrhythmic prodrugs amiodarone and dronedarone are extensively metabolized by CYP2J2; specific CYP2J2 metabolites include N-desbutyldronedarone and N-desethylamiodarone, potent [reversible/irreversible] inhibitors of CYP2J2.

  7. Tanshinone IIA exerts its anticancer effect by inhibiting CYP2J2 activity in HepG2 cells.

  8. CYP2J2 expression showed significant upregulation (P<0.05) during Cy treatment before stem cell transplantation

  9. Here we present the detection of substrate binding to cytochrome P450-2J2 (CYP2J2), the predominant P450 (zeige CYP2B6 Proteine) in the human heart, using a combination of Nanodisc technology and a nanohole plasmonic sensor

  10. Our results suggest that individuals with any conventional risk factor for MI along with CYP2J2*7 variant allele may be predisposed to risk of myocardial infarct in South Indian population

CYP2J2 Protein Überblick

Protein Überblick

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is thought to be the predominant enzyme responsible for epoxidation of endogenous arachidonic acid in cardiac tissue.

Genbezeichner und Symbole assoziert mit CYP2J2

  • cytochrome P450, family 2, subfamily j, polypeptide 16 (Cyp2j16)
  • cytochrome P450, family 2, subfamily J, polypeptide 2 (CYP2J2)
  • hypothetical LOC530929 (CYP2J2)
  • cytochrome P450, family 2, subfamily J, polypeptide 2 (cyp2j2)
  • cytochrome P450, family 2, subfamily j, polypeptide 4 (Cyp2j4)
  • CPJ2 Protein
  • CYP2J2 Protein
  • MGC134319 Protein
  • RGD1561242 Protein

Bezeichner auf Proteinebene für CYP2J2

cytochrome P450, family 2, subfamily J, polypeptide 2 , hypothetical LOC530929 , cytochrome P450, family 2, subfamily J-like , CYPIIJ2 , arachidonic acid epoxygenase , cytochrome P450 2J2 , cytochrome P450, subfamily IIJ (arachidonic acid epoxygenase) polypeptide 2 , flavoprotein-linked monooxygenase , microsomal monooxygenase

GENE ID SPEZIES
502969 Rattus norvegicus
424678 Gallus gallus
521656 Bos taurus
530929 Bos taurus
100158388 Xenopus laevis
1573 Homo sapiens
65210 Rattus norvegicus
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