anti-Cytochrome B-245, beta Polypeptide (CYBB) Antikörper

Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. Zusätzlich bieten wir Ihnen CYBB Kits (9) und CYBB Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CYBB 1536 P04839
CYBB 13058 Q61093
CYBB 66021  
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Top anti-CYBB Antikörper auf antikoerper-online.de

Showing 10 out of 115 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB WB Suggested Anti-CYBB Antibody Titration: 1.0ug/mlELISA Titer: 1:62500Positive Control: THP-1 cell lysate IHC Information: Lung, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert IF (cc), IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat pancreas labeled with Anti NOX2/gp91phox Polyclonal Antibody, Unconjugated (ABIN750688) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-NOX2/gp91phox Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
315,94 €
Details
Human Maus Unkonjugiert WB 0.1 mL Anmelden zum Anzeigen 3 bis 4 Tage
437,80 €
Details
Human Maus Unkonjugiert ICC, IF, IHC (p), WB 0.1 mL Anmelden zum Anzeigen 3 bis 4 Tage
437,80 €
Details
Maus Maus Unkonjugiert IF, WB Western blot analysis of gp91[phox] on mouse macrophage lysate. Lane 1: 1:1000, lane 2: 1:2000, lane 3: 1:4000 dilution of gp91[phox] antibody. Immunofluorescent staining of mouse macrophage cells with gp91[phox] antibody. 50 μg Anmelden zum Anzeigen 2 bis 4 Tage
146,73 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti-NOX2/gp91phox antibody, Western blotting Lane 1: HELA Cell Lysate Lane 2: JURKAT Cell Lysate Lane 3: MCF-7 Cell Lysate Lane 4: SMMC Cell Lysate Anti-NOX2/gp91phox antibody, IHC(P) IHC(P): Human Intestinal Cancer Tissue 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
298,57 €
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Western Blot: CYBB/NOX2 Antibody [NBP2-13037] - Extracts from HT29cells. 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
341,00 €
Details
Human Maus Unkonjugiert IHC (p), WB 0.25 mg Anmelden zum Anzeigen 7 bis 9 Tage
517,00 €
Details
Human Kaninchen Unkonjugiert ELISA, IHC (p), WB Western Blot (WB) analysis of K562 cells using gp91-phox Polyclonal Antibody. 100 μL Anmelden zum Anzeigen 13 Days
154,33 €
Details
Human Kaninchen Unkonjugiert ELISA, WB Western Blot (WB) analysis of specific cells using gp91-phox Polyclonal Antibody. 100 μL Anmelden zum Anzeigen 13 Days
154,33 €
Details

CYBB Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

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Am meisten referenzierte anti-CYBB Antikörper

  1. Human Polyclonal CYBB Primary Antibody für IF (cc), IF (p) - ABIN750688 : Dalaklioglu, Tasatargil, Kale, Tanriover, Dilmac, Erin: Metastatic breast carcinoma induces vascular endothelial dysfunction in Balb-c mice: Role of the tumor necrosis factor-? and NADPH oxidase. in Vascular pharmacology 2013 (PubMed)
    Zeige alle 5 Referenzen für 750688

  2. Human Polyclonal CYBB Primary Antibody für IHC (p), WB - ABIN3044252 : Liao, Liu, Guo, Zhang, Zhang: Oxidative burst of circulating neutrophils following traumatic brain injury in human. in PLoS ONE 2013 (PubMed)
    Zeige alle 4 Referenzen für 3044252

  3. Mouse (Murine) Monoclonal CYBB Primary Antibody für IF, WB - ABIN968523 : Jacobsen, Skalnik: YY1 binds five cis-elements and trans-activates the myeloid cell-restricted gp91(phox) promoter. in The Journal of biological chemistry 1999 (PubMed)
    Zeige alle 4 Referenzen für 968523

  4. Human Polyclonal CYBB Primary Antibody für IHC, IHC (p) - ABIN4301440 : Rajtik, Carnicka, Szobi, Giricz, O-Uchi, Hassova, Svec, Ferdinandy, Ravingerova, Adameova: Oxidative activation of CaMKIIδ in acute myocardial ischemia/reperfusion injury: A role of angiotensin AT1 receptor-NOX2 signaling axis. in European journal of pharmacology 2016 (PubMed)
    Zeige alle 3 Referenzen für 4301440

  5. Human Monoclonal CYBB Primary Antibody für ICC, IF - ABIN1042596 : Burritt, Quinn, Jutila, Bond, Jesaitis: Topological mapping of neutrophil cytochrome b epitopes with phage-display libraries. in The Journal of biological chemistry 1995 (PubMed)
    Zeige alle 2 Referenzen für 1042596

  6. Human Monoclonal CYBB Primary Antibody für WB - ABIN1042597 : Baniulis, Burritt, Taylor, Dinauer, Heyworth, Parkos, Magnusson, Jesaitis: Monoclonal antibody CL5 recognizes the amino terminal domain of human phagocyte flavocytochrome b558 large subunit, gp91phox. in European journal of haematology 2005 (PubMed)

  7. Human Polyclonal CYBB Primary Antibody für WB - ABIN2781794 : Fink, Duval, Martel, Soucy-Faulkner, Grandvaux: Dual role of NOX2 in respiratory syncytial virus- and sendai virus-induced activation of NF-kappaB in airway epithelial cells. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)

Weitere Antikörper gegen CYBB Interaktionspartner

Zebrafish Cytochrome B-245, beta Polypeptide (CYBB) Interaktionspartner

  1. The nox1 (zeige NOX1 Antikörper), nox2/cybb expression in zebrafish during early nervous system development from 12 to 48 hours post fertilization

Rabbit Cytochrome B-245, beta Polypeptide (CYBB) Interaktionspartner

  1. Data indicate that NADPH oxidase (zeige NOX1 Antikörper) NOx2 inhibition attenuates endoplasmic reticulum (ER) stress and apoptosis.

Human Cytochrome B-245, beta Polypeptide (CYBB) Interaktionspartner

  1. NOX2, NOX4 (zeige NOX4 Antikörper), and mitochondrial-derived reactive oxygen species contribute to angiopoietin-1 (zeige ANGPT1 Antikörper) signaling and angiogenic responses in endothelial cells.

  2. PFK-2 (zeige PFKFB3 Antikörper) seems to be a strategic element that links NADPH oxidase (zeige NOX1 Antikörper) activation and glycolysis modulation, and, as such, is proposed as a potential therapeutic target in inflammatory diseases.

  3. data support NOX2 as a critical component of the suppressive machinery of CD8 (zeige CD8A Antikörper) Tregs and suggest that repairing NOX2 deficiency in these cells may protect older individuals from tissue-destructive inflammatory disease, such as large-vessel vasculitis.

  4. CD8 (zeige CD8A Antikörper)+ T cells in close contact with target T cells release NADPH oxidase 2-containing microvesicles that inhibit TCR activation by elevating ROS (zeige ROS1 Antikörper) and thereby reducing phosphorylation of the TCR-associated kinase ZAP70 (zeige ZAP70 Antikörper).

  5. Thioredoxin (zeige TXN Antikörper) attenuates oxidized low-density lipoprotein induced oxidative stress in human umbilical vein endothelial cells by reducing NOX2-NOX4 (zeige NOX4 Antikörper) activity.

  6. Nox4 (zeige NOX4 Antikörper)-derived H2O2 in part activates Nox2 to increase mitochondrial ROS (zeige ROS1 Antikörper) via pSer36-p66Shc (zeige SHC1 Antikörper), thereby enhancing VEGFR2 (zeige KDR Antikörper) signaling and angiogenesis in endothelial cells.

  7. Cytochrome b558 (zeige CYBA Antikörper) also traffics from a lysosomal pool to phagosomes and this is required to replenish oxidatively damaged NOX2.

  8. Nox4 (zeige NOX4 Antikörper) should contribute to the pathological processes insubarachnoid hemorrhage(SAH (zeige ACSM3 Antikörper))-induced early brain injury (EBI (zeige TBL1X Antikörper)), and there was not an overlay effect of Nox2 inhibition and Nox4 (zeige NOX4 Antikörper) inhibition on preventing SAH (zeige ACSM3 Antikörper)-induced EBI (zeige TBL1X Antikörper).

  9. NADPH oxidase (zeige NOX1 Antikörper) promotes Parkinsonian phenotypes by impairing autophagic flux in an mTORC1-independent fashion in a cellular model of Parkinson's disease

  10. TLR4 (zeige TLR4 Antikörper)- and TLR2 (zeige TLR2 Antikörper)-induced IRAK (zeige IRAK1 Antikörper)-ERK (zeige EPHB2 Antikörper) pathway cross-talks with p67phox (zeige NCF2 Antikörper)-Nox-2 for reactive oxygen species generation, thus regulating IL-1beta (zeige IL1B Antikörper) transcription and processing in monocytic cells.

Cow (Bovine) Cytochrome B-245, beta Polypeptide (CYBB) Interaktionspartner

  1. Data indicate that the efficiency of NADPH oxidase (zeige NOX1 Antikörper) enzymatic activity is higher at endoplasmic reticulum (ER).

  2. A p47(phox) and Src kinase (zeige CSK Antikörper) activation of peroxide production by Nox2 appears to be an important contributor to vascular contractile mechanisms mediated through activation of protein kinase C (zeige PKC Antikörper)

Mouse (Murine) Cytochrome B-245, beta Polypeptide (CYBB) Interaktionspartner

  1. Redox-dependent regulation of EGFR (zeige EGFR Antikörper) activation in airway epithelial cells was found to strongly depend on activation of either DUOX1 (zeige DUOX1 Antikörper) or NOX2.

  2. NOX2 signaling in macrophages participates in the pathogenesis of obesity, and reinforce a key role for macrophage inflammation in diet-induced metabolic and neurologic decline

  3. Studies in knockout and knock-in mice showed that the phospholipase A2 (zeige YWHAZ Antikörper) activity of peroxiredoxin 6 (zeige PRDX6 Antikörper) activates NOX2 in cultured pulmonary endothelial cells and alveolar macrophages, clarifying the metabolism of lysophosphatidyl chold to lysophosphatidic acid.

  4. NOX2 knockout mice had significantly lower blood pressure than littermate controls, with both endothelial cells and myeloid cells having a deficiency in NOX2.

  5. Data show that pan (zeige SUPT6H Antikörper)-NOX-inhibitor APX (zeige SHROOM1 Antikörper)-115 treatment decreased NADPH oxidase (zeige NOX1 Antikörper) (Nox) Nox1 (zeige NOX1 Antikörper), Nox2, and Nox4 (zeige NOX4 Antikörper) protein expression in the kidney.

  6. NOX2 regulates proinflammatory TLR signaling and alveolar remodeling induced by a single dose of lipopolysaccharides.

  7. a deficiency in MyD88 (zeige MYD88 Antikörper) or CybB is associated with impaired bacterial clearance and increased granuloma formation in the lung.

  8. NOX2 isoform was first discovered as a component of the oxidative burst in neutrophils and is a complex consisting of several cytosolic subunits (p47phox (zeige NCF1 Antikörper), p67phox (zeige NCF2 Antikörper), p40phox (zeige NCF4 Antikörper), and Rac1 or Rac2 (zeige RAC2 Antikörper)) and a membrane-associated cytochrome b558 (zeige CYBA Antikörper) reductase made up of gp91phox and p22phox (zeige CYBA Antikörper) subunits.

  9. Macrophage-produced HMGB1 (zeige HMGB1 Antikörper) leads to aortic inflammation and acts as a trigger for CD4 (zeige CD4 Antikörper)(+) T-cell-produced IL-17 (zeige IL17A Antikörper) during abdominal aortic aneurysm formation. HMGB1 (zeige HMGB1 Antikörper) release is dependent on Nox2 activation, which can be inhibited by MSCs leading to attenuation of proinflammatory cytokines and protection against AAA (zeige AAAS Antikörper) formation.

  10. NOX2 is important for ROS (zeige ROS1 Antikörper) generation induced by both the GPCR (zeige GPBAR1 Antikörper) and the GPVI (zeige GP6 Antikörper)/ITAM signaling pathways in blood platelets.

Pig (Porcine) Cytochrome B-245, beta Polypeptide (CYBB) Interaktionspartner

  1. sub-vasomotor concentration of ET-1 (zeige EDN1 Antikörper) leads to vascular dysfunction by impairing endothelium-dependent NO-mediated dilation via p38 (zeige MAPK14 Antikörper) kinase-mediated production of superoxide from NADPH oxidase (zeige NOX1 Antikörper) following ETA receptor activation

  2. Reactive oxygen species generated by NADPH oxidase (zeige NOX1 Antikörper) contribute to the aberrant pulmonary arterial responses in piglets exposed to 3 days of hypoxia.

  3. Upregulation of PPAR-gamma (zeige PPARG Antikörper) and NADPH (zeige NQO1 Antikörper) oxidases are involved in restenosis.

CYBB Antigen-Profil

Protein Überblick

Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase\; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.

Genbezeichner und Symbole assoziert mit CYBB

  • cytochrome b-245, beta polypeptide (chronic granulomatous disease) (cybb) Antikörper
  • cytochrome b-245, beta polypeptide (cybb) Antikörper
  • cytochrome b-245, beta polypeptide (chronic granulomatous disease) (CYBB) Antikörper
  • cytochrome b-245, beta polypeptide (CYBB) Antikörper
  • cytochrome b-245 beta polypeptide (CYBB) Antikörper
  • cytochrome b-245, beta polypeptide (Cybb) Antikörper
  • NADPH oxidase heavy chain subunit (GP91-PHOX) Antikörper
  • AMCBX2 Antikörper
  • C88302 Antikörper
  • Cgd Antikörper
  • CGD91-phox Antikörper
  • CYBB Antikörper
  • Cyd Antikörper
  • GP91-1 Antikörper
  • Gp91-phox Antikörper
  • GP91PHOX Antikörper
  • NOX1 Antikörper
  • Nox2 Antikörper
  • p91-PHOX Antikörper
  • zgc:64144 Antikörper

Bezeichner auf Proteinebene für CYBB

cytochrome b-245, beta polypeptide , gp91 , NADPH oxidase 2 , cytochrome b-245, beta polypeptide (chronic granulomatous disease) , Cytochrome b-245 heavy chain , NADPH oxidase heavy chain subunit , NADPH oxidase 1 , NADPH oxidase flavocytochrome b subunit , cytochrome b-245 heavy chain , gp91-phox , CGD91-phox , cytochrome b(558) subunit beta , cytochrome b558 subunit beta , heme-binding membrane glycoprotein gp91phox , neutrophil cytochrome b 91 kDa polypeptide , p22 phagocyte B-cytochrome , superoxide-generating NADPH oxidase heavy chain subunit , gp91-1 , endothelial type gp91-phox , predicted NADPH oxidase-2

GENE ID SPEZIES
393386 Danio rerio
595081 Xenopus (Silurana) tropicalis
696542 Macaca mulatta
444353 Xenopus laevis
100036757 Ovis aries
100270807 Salmo salar
100008801 Oryctolagus cuniculus
1536 Homo sapiens
418581 Gallus gallus
281112 Bos taurus
13058 Mus musculus
66021 Rattus norvegicus
491825 Canis lupus familiaris
397108 Sus scrofa
Ausgewählte Anbieter für anti-CYBB (CYBB) Antikörper
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