Cystatin E/M (CST6) ELISA Kits

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Zusätzlich bieten wir Ihnen CST6 Antikörper (90) und CST6 Proteine (16) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
CST6 1474 Q15828
Anti-Maus CST6 CST6 73720  
Anti-Ratte CST6 CST6 171096  
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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.053 ng/mL 0.156-10 ng/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
875,63 €
Details

Weitere ELISA Kits für CST6 Interaktionspartner

Human Cystatin E/M (CST6) Interaktionspartner

  1. Data suggest that melanoma cells internalize/absorb cystatin C (zeige CST3 ELISA Kits) from culture media, leading to increased intracellular cystatin C (zeige CST3 ELISA Kits) levels; cystatin E/M is internalized as well but at modest rate due to down-regulation of cell migration; however, the effect of intracellular cystatin E/M on down-regulation of legumain (zeige LGMN ELISA Kits) activity is pronounced.

  2. Results provide evidence that cystatin E/M is a tumor suppressor gene which plays an important role in the regulation of NF-kappaB (zeige NFKB1 ELISA Kits).

  3. Low CST6 expression is associated with breast cancer.

  4. Developed a Methylation-Sensitive High Resolution Melting Analysis (MS-HRMA) assay for the investigation of CST6 promoter methylation in breast cancer patients.CST6 promoter was methylated in 39/80 of FFPEs.

  5. The CST6 promoter is highly methylated in circulating cell-free DNA of breast cancer patients, but not in healthy individuals.

  6. Data show a regulatory role of cystatin E/M in controlling both intra- and extracellular legumain (zeige LGMN ELISA Kits) activity.

  7. The ectopic expression of CST6 in cancer cells rescued mice from overt osteolytic metastasis and deaths in the animal study, while CST6 knockdown markedly enhanced cancer cell bone metastasis and shortened animal survival.

  8. An association between the quantity of CST6 methylation and the expression statuses of estrogen receptor (zeige ESR1 ELISA Kits), progesterone receptor (zeige PGR ELISA Kits), and HER4 (zeige ERBB4 ELISA Kits) in tumor tissues was found

  9. the level of cystatin E/M regulates legumain (zeige LGMN ELISA Kits) activity and hence the invasive potential of human melanoma cells

  10. CST6 is not a major gene contributing to type 1 and 2 harlequin ichthyosis

Mouse (Murine) Cystatin E/M (CST6) Interaktionspartner

  1. conclude that a tightly regulated balance between cathepsin L (zeige CTSL1 ELISA Kits) and cystatin M/E is essential for tissue integrity in epidermis, hair follicles, and corneal epithelium

  2. cystatin M/E has a role in skin barrier formation and a potential role as a tumor suppressor gene [review]

CST6 Antigen-Profil

Beschreibung des Gens

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. This gene encodes a cystatin from the type 2 family, which is down-regulated in metastatic breast tumor cells as compared to primary tumor cells. Loss of expression is likely associated with the progression of a primary tumor to a metastatic phenotype.

Genbezeichner und Symbole assoziert mit Cystatin E/M (CST6) ELISA Kits

  • cystatin E/M (CST6) Antikörper
  • cystatin E/M (Cst6) Antikörper
  • 1110017E11Rik Antikörper
  • CST6 Antikörper
  • ichq Antikörper
  • N28197 Antikörper

Bezeichner auf Proteinebene für Cystatin E/M (CST6) ELISA Kits

cystatin E/M , cystatin M , cystatin-M , cystatin 6 , cystatin M/E , cystatin-6 , cystatin-E , cysteine proteinase inhibitor , harlequin ichthyosis , harlequin ichthysosis , cystatin N

GENE ID SPEZIES
466668 Pan troglodytes
503685 Bos taurus
714999 Macaca mulatta
1474 Homo sapiens
483719 Canis lupus familiaris
73720 Mus musculus
171096 Rattus norvegicus
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