Cystatin C Proteine (CST3)

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Zusätzlich bieten wir Ihnen Cystatin C Antikörper (457) und Cystatin C Kits (115) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
CST3 1471 P01034
CST3 13010 P21460
CST3 25307 P14841
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Top Cystatin C Proteine auf antikoerper-online.de

Showing 10 out of 78 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Human Cells Human His tag 10 μg Anmelden zum Anzeigen 18 bis 20 Tage
287,50 €
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HOST_Human Cells Maus His tag 10 μg Anmelden zum Anzeigen 18 bis 20 Tage
287,50 €
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HOST_Escherichia coli (E. coli) Human His tag 50 μg Anmelden zum Anzeigen 11 bis 15 Tage
387,62 €
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HOST_Human Cells Human Unkonjugiert 10 μg Anmelden zum Anzeigen 18 bis 20 Tage
287,50 €
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HOST_Human Cells Ratte His tag 10 μg Anmelden zum Anzeigen 18 bis 20 Tage
287,50 €
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HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
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HOST_Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
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HOST_Escherichia coli (E. coli) Hund His tag 50 μg Anmelden zum Anzeigen 11 bis 15 Tage
476,19 €
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HOST_HEK-293 Cells Human Unkonjugiert 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
861,37 €
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HOST_Mammalian Cells Human His tag   50 μg Anmelden zum Anzeigen 8 bis 9 Tage
523,81 €
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CST3 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , , , ,
, ,
Mouse (Murine) ,
,
Rat (Rattus) , ,

Am meisten referenzierte Cystatin C Proteine

  1. Human CST3 Protein expressed in Human Cells - ABIN2002851 : Janowski, Kozak, Jankowska, Grzonka, Grubb, Abrahamson, Jaskolski: Human cystatin C, an amyloidogenic protein, dimerizes through three-dimensional domain swapping. in Nature structural biology 2001 (PubMed)
    Zeige alle 5 Referenzen für 2002851

  2. Human CST3 Protein expressed in Human Cells - ABIN2002853 : Kos, Stabuc, Cimerman, Brünner: Serum cystatin C, a new marker of glomerular filtration rate, is increased during malignant progression. in Clinical chemistry 1999 (PubMed)
    Zeige alle 5 Referenzen für 2002853

  3. Rat (Rattus) CST3 Protein expressed in Human Cells - ABIN2009079 : Fricker, Wiesli, Brändle, Schwegler, Schmid: Impact of thyroid dysfunction on serum cystatin C. in Kidney international 2003 (PubMed)
    Zeige alle 5 Referenzen für 2009079

  4. Mouse (Murine) CST3 Protein expressed in Human Cells - ABIN2007555 : Kaeser, Herzig, Coomaraswamy, Kilger, Selenica, Winkler, Staufenbiel, Levy, Grubb, Jucker: Cystatin C modulates cerebral beta-amyloidosis. in Nature genetics 2007 (PubMed)
    Zeige alle 5 Referenzen für 2007555

  5. Human CST3 Protein expressed in Escherichia coli (E. coli) - ABIN1098585 : Liu: Evaluation of serum cystatin C for diagnosis of acute rejection after renal transplantation. in Transplantation proceedings 2012 (PubMed)

Weitere Proteine zu Cystatin C (CST3) Interaktionspartnern

Human Cystatin C (CST3) Interaktionspartner

  1. Data suggest that melanoma cells internalize/absorb cystatin C from culture media, leading to increased intracellular cystatin C levels; cystatin E/M (zeige CST6 Proteine) is internalized as well but at modest rate due to down-regulation of cell migration; however, the effect of intracellular cystatin E/M (zeige CST6 Proteine) on down-regulation of legumain (zeige LGMN Proteine) activity is pronounced.

  2. An elevated preoperative Cys (zeige DNAJC5 Proteine)-C level was demonstrated to be related with worse survival in patients with renal cell carcinoma (zeige MOK Proteine)(RCC (zeige XRCC1 Proteine)). Measuring preoperative serum Cys (zeige DNAJC5 Proteine)-C might be a simple way for finding poor prognostic patients and patients with elevated preoperative Cys (zeige DNAJC5 Proteine)-C level should be more closely followed up

  3. Acute kidney injury is common following deliberate self-poisoning with a combination washing powder containing oxalic acid and potassium permanganate and cystatin C monitoring may under estimate the severity of poisoning.

  4. Cystatin C significantly decreased the lipopolysaccharide-stimulated release and expression of interleukin-1beta and tumor necrosis factor-alpha (zeige TNF Proteine) in monocyte and peripheral blood mononuclear cultures from healthy donors and Crohn's patients. Cystatin C was internalized by monocytes via an active endocytic process, decreased phosphorylation of the MAP kinase (zeige MAPK1 Proteine) pathway ERK-1 (zeige MAPK3 Proteine)/2, and altered surface markers.

  5. Fibrillation of CysC therefore likely initiates from the monomer and does not require domain-swapping. The non-swapped oligomers likely represent a dead-end (zeige DND1 Proteine) offshoot of the amyloid pathway and must dissociate to monomers prior to rearranging to amyloid fibrils. These prefibrillar CysC oligomers were potent inhibitors of aggregation of the Alzheimer's-related peptide, beta-amyloid.

  6. CysC plays an important regulatory role in combating cell death via the autophagic pathway in atherosclerosis.

  7. Data show that cystatin C deposition in minimally affected samples was limited to the basement membrane (BM) between the dermis and epidermis.

  8. Urinary cystatin C levels in the acute kidney injury (AKI) preterm infant group were not significantly higher than in no-AKI group on day of life 1, 3 and 7.

  9. Serum cystatin C level was found to be associated with the development and worsening of AKI [Acute kidney injury ] in ICU [intensive care unit ] patients with sepsis.

  10. Elevated cystatin C levels at admission were independently associated with impaired myocardial perfusion, poor cardiac functional recovery and development of congestive heart failure in patients with anterior STEMI undergoing PCI (zeige SERPINA5 Proteine).

Mouse (Murine) Cystatin C (CST3) Interaktionspartner

  1. CysC plays an important regulatory role in combating cell death via the autophagic pathway in atherosclerosis.

  2. Data (including data from studies in mutant mice) suggest that up-regulation of Cst3, as observed in plasma of mice with type 2 diabetes, down-regulates insulin (zeige INS Proteine) signaling and promotes endoplasmic reticulum stress in hepatocytes but not in myotubes.

  3. Cystatin C is a potential pathogenic signal triggering neurodegeneration in multiple system atrophy.

  4. The neuroprotective activity of CysC against Amyotrophic lateral sclerosis-linked mutant Cu/Zn-superoxide dismutase (SOD1 (zeige SOD1 Proteine))-mediated toxicity.

  5. an important role for macrophages, DC, and ROS (zeige ROS1 Proteine) in diseases associated with the protease inhibitory activity or amyloidogenic properties of cystatin C.

  6. APP (zeige APP Proteine) expression stimulates NSPC proliferation; this effect is mediated via an increase in cystatin C secretion

  7. Cystatin C, a protein targeted to the classical secretory pathway by its signal peptide sequence, is secreted by primary neurons in at least 9 different cystatin C glycoforms associated with exosomes.

  8. The lack of cystatin C enhances Collagen-induced arthritis and primarily affects in vivo priming of the immune system

  9. Inflammation causes downregulation of cystatin C expression in dendritic cells and reduces serum CstC levels.

  10. Data show that the absence of cystatin C reduced epithelial cell apoptosis but increased proliferation in skin.

Pig (Porcine) Cystatin C (CST3) Interaktionspartner

  1. CST3 may be required to remodel endometrial and placental tissues for close apposition between maternal and fetal vasculatures and to facilitate transplacental transport of gases, micronutrients (amino acids, glucose), and macromolecules (proteins).

Rabbit Cystatin C (CST3) Interaktionspartner

  1. Increased production of cystatin C in osteoarthritis synovium does not alleviate synovitis or cartilage pathology.

Cow (Bovine) Cystatin C (CST3) Interaktionspartner

  1. Cystatin C in milk basic protein (MBP (zeige MBP Proteine)) is suggested as one of the factors inhibiting bone resorption

Cystatin C (CST3) Protein Überblick

Protein Überblick

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease.

Genbezeichner und Symbole assoziert mit Cystatin C Proteine (CST3)

  • cystatin C (CST3)
  • cystatin C (cst3)
  • cystatin C (amyloid angiopathy and cerebral hemorrhage) (cst3)
  • hypothetical protein (cystatin 3)
  • cystatin C (Cst3)
  • ARMD11 Protein
  • CYSC Protein
  • fb51d07 Protein
  • wu:fb24g06 Protein
  • wu:fb51d07 Protein
  • wu:fc55f03 Protein
  • zgc:136227 Protein

Bezeichner auf Proteinebene für Cystatin C Proteine (CST3)

cystatin , egg-white cystatin , ovocystatin , cystatin C , cystatin-C , cystatin 3 , hypothetical protein , bA218C14.4 (cystatin C) , cystatin-3 , gamma-trace , neuroendocrine basic polypeptide , post-gamma-globulin , Cystatin C (cysteine proteinase inhibitor) , colostrum thiol proteinase inhibitor , cystatin C (amyloid angiopathy and cerebral hemorrhage)

GENE ID SPEZIES
396497 Gallus gallus
733234 Xenopus laevis
791878 Danio rerio
100379852 Xenopus (Silurana) tropicalis
100462660 Felis catus
3238896 Cotesia congregata bracovirus
1471 Homo sapiens
13010 Mus musculus
733672 Sus scrofa
25307 Rattus norvegicus
100009450 Oryctolagus cuniculus
281102 Bos taurus
574313 Macaca mulatta
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