anti-Cystathionine-beta-Synthase (CBS) Antikörper

The protein encoded by CBS acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. Zusätzlich bieten wir Ihnen Cystathionine-beta-Synthase Proteine (30) und Cystathionine-beta-Synthase Kits (17) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CBS 24250 P32232
CBS 12411 Q91WT9
CBS 875 P35520
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Top anti-Cystathionine-beta-Synthase Antikörper auf antikoerper-online.de

Showing 10 out of 123 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Human Kaninchen Unkonjugiert FACS, IF, IHC (p), WB Western blot analysis of CBS Antibody (Center) (ABIN390947) in mouse kidney tissue lysates (35 µg/lane). CBS (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with CBS Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti-CBS antibody, Western blotting Lane 1: SMMC Cell Lysate Lane 2: U87 Cell Lysate Lane 3: HELA Cell Lysate Lane 4: MM231 Cell Lysate Anti-CBS antibody, IHC(P) IHC(P): Human Liver Cancer Tissue 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$200.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti- CBS antibody, Western blotting All lanes: Anti CBS  at 0.5ug/ml WB: Recombinant human CBS Protein 0.5ng Predicted bind size: 42KD Observed bind size: 42KD 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$200.00
Details
Human Kaninchen Unkonjugiert FACS, IF, IHC, WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$245.00
Details
Human Kaninchen Unkonjugiert FACS, IF, IHC, WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$245.00
Details
Human Maus Unkonjugiert IF, IHC (p), ELISA, WB Detection limit for recombinant GST tagged CBS is approximately 0.03ng/ml as a capture antibody. Immunoperoxidase of monoclonal antibody to CBS on formalin-fixed paraffin-embedded human liver. [antibody concentration 3 ug/ml] 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$430.00
Details
Human Maus Unkonjugiert IHC (p), IP, RNAi, ELISA, WB Immunoperoxidase of monoclonal antibody to CBS on formalin-fixed paraffin-embedded human hepatocellular carcinoma. [antibody concentration 3 ug/ml] CBS monoclonal antibody (M01), clone 3E1 Western Blot analysis of CBS expression in HeLa . 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$430.00
Details
Human Maus Unkonjugiert ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL Anmelden zum Anzeigen 11 bis 12 Tage
$298.57
Details
Maus Kaninchen Unkonjugiert IHC, WB Western blot analysis of extracts of various cell lines, using CBS antibody. 100 μL Anmelden zum Anzeigen 13 bis 14 Tage
$302.50
Details

CBS Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Cystathionine-beta-Synthase Antikörper

  1. Human Monoclonal CBS Primary Antibody für IHC (p), IP - ABIN560206 : Schicho, Krueger, Zeller, Von Weyhern, Frieling, Kimura, Ishii, De Giorgio, Campi, Schemann: Hydrogen sulfide is a novel prosecretory neuromodulator in the Guinea-pig and human colon. in Gastroenterology 2006 (PubMed)
    Show all 38 Pubmed References

  2. Human Polyclonal CBS Primary Antibody für ELISA, WB - ABIN560204 : Ali, Whiteman, Low, Moore: Hydrogen sulphide reduces insulin secretion from HIT-T15 cells by a KATP channel-dependent pathway. in The Journal of endocrinology 2007 (PubMed)
    Show all 11 Pubmed References

  3. Cow (Bovine) Polyclonal CBS Primary Antibody für IHC, WB - ABIN2782348 : Urreizti, Asteggiano, Bermudez, Córdoba, Szlago, Szlago, Grosso, de Kremer, Vilarinho, DAlmeida, Martínez-Pardo, Peña-Quintana, Dalmau, Bernal, Briceño, Couce, Rodés, Vilaseca, Balcells, Grinberg: The p.T191M mutation of the CBS gene is highly prevalent among homocystinuric patients from Spain, Portugal and South America. in Journal of human genetics 2006 (PubMed)
    Show all 9 Pubmed References

  4. Human Polyclonal CBS Primary Antibody für WB - ABIN514085 : Qi, Zhou, Xiao, Tao, Gu, Jiang, Xu: Promoter demethylation of cystathionine-?-synthetase gene contributes to inflammatory pain in rats. in Pain 2012 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal CBS Primary Antibody für ELISA, WB - ABIN560205 : Li, Chen, Muh, Li: Hyperhomocysteinemia associated with decreased renal transsulfuration activity in Dahl S rats. in Hypertension 2006 (PubMed)
    Show all 2 Pubmed References

  6. Human Polyclonal CBS Primary Antibody für FACS, IF - ABIN1881141 : Lee, Mariappan, Feliers, Cavaglieri, Sataranatarajan, Abboud, Choudhury, Kasinath: Hydrogen sulfide inhibits high glucose-induced matrix protein synthesis by activating AMP-activated protein kinase in renal epithelial cells. in The Journal of biological chemistry 2012 (PubMed)
    Show all 2 Pubmed References

  7. Human Monoclonal CBS Primary Antibody für IF, IHC (p) - ABIN514088 : Majtan, Freeman, Smith, Burstyn, Kraus: Purification and characterization of cystathionine ?-synthase bearing a cobalt protoporphyrin. in Archives of biochemistry and biophysics 2011 (PubMed)

Weitere Antikörper gegen Cystathionine-beta-Synthase Interaktionspartner

Chimpanzee Cystathionine-beta-Synthase (CBS) Interaktionspartner

Mouse (Murine) Cystathionine-beta-Synthase (CBS) Interaktionspartner

  1. showed that N-homocysteinylation of collagen in Cbs(-/-) mice impairs its cross-linking

  2. the findings of this study indicate that a deficiency in 3MST does not significantly affect endotoxemia, while a deficiency in CBS or CSE (zeige CTH Antikörper) slightly ameliorates the outcome of LPS (zeige TLR4 Antikörper)-induced endotoxemia in vivo.

  3. These data confirm a key role for the H2S-generating enzymes Cbs and Cth (zeige CTH Antikörper) in pulmonary vascular development and homeostasis and in lung alveolarization.

  4. genetic deficiency results in reduced Tet1 (zeige TET1 Antikörper) and Tet2 (zeige TET2 Antikörper) expression, which leads to hypermethylation of Foxp3 (zeige FOXP3 Antikörper), and impairment of Treg cell differentiation and immune homeostasis.

  5. Elevated homocytsteine levels in the CBS-/+ mouse skeletal muscles caused diminished anti-oxidant capacity and contributed to enhanced total protein as well as PGC-1alpha (zeige PPARGC1A Antikörper) specific nitrotyrosylation after ischemia.

  6. CBS disruption causes embryo retention and developmental delay in the mouse oviduct.

  7. CBS is present in adrenocortical cells and accounts for H2S generation in adrenal glands. CBS is critical for maintenance of mitochondrial function and glucocorticoid production in adrenal cortex.

  8. Elevating endogenous H2S via CBS over-expression in immortalized microglia not only reduced the expression of pro-inflammatory M1 genes, but also enhanced the anti-inflammatory M2 marker IL-10 (zeige IL10 Antikörper) production.

  9. Cbs protein expression is upregulated in brain cortex following traumatic brain injury.

  10. Brain of mice heterozygous for Cbs displays overexpression of DYR (zeige DHFR Antikörper) kinase and SAH (zeige ACSM3 Antikörper) hydrolase.

Human Cystathionine-beta-Synthase (CBS) Interaktionspartner

  1. Inducible expression of CBS and CSE was found to be associated with a mineralizing phenotype in mesenchymal stem cells transitioning to mineralizing osteoblasts.

  2. SNPs in CBS were not related to relevant changes in homocysteine levels in coronary artery disease patients or controls.

  3. The CBS rs2124459 was associated with a reduced risk of cleft palate in both French and Belgian populations. These results highlight the prominent involvement of the vitamin B6-dependent transsulfuration pathway of homocysteine in orofacial cleft risk and the interest for evaluating vitamin B6 status in further population studies.

  4. There is no ordinary conjunction between human CBS and severe sepsis/septic shock, but CBS genotypes are involved in disease susceptibility.

  5. Oligomeric status of human cystathionine beta-synthase modulates AdoMet (zeige MAT1A Antikörper) binding.

  6. Significant interactions were observed among the methylenetetrahydrofolate reductase (MTHFR (zeige MTHFR Antikörper); C677T; A1298C) and cystathionine-beta-synthase (CBS; T833C/844ins68, G919A) polymorphisms in the results for homocysteine (Hcy) levels, where heterozygous had higher values.

  7. results indicate that binding of SAM (zeige TTN Antikörper) to regulatory and stabilizing sites in CBS may have evolved to display an exquisite thermodynamic and structural specificity towards SAM (zeige TTN Antikörper) as well as the ability to transduce the allosteric signal responsible for CBS activation.

  8. CBS 844ins68 polymorphisms were not associated with Oral squamous cell carcinoma risk in southeastern Brazilians.

  9. This is the first mutational analysis of CBS done in a Filipino patient with classic homocystinuria who presented with a novel duplication mutation and a novel missense mutation.

  10. Two novel compound heterozygous mutations in the CBS gene, c.407T > C (p. L136P) and c.473C > T (p.A158V), were identified in the three patients of a Han Chinese family with homocystinuria

Cow (Bovine) Cystathionine-beta-Synthase (CBS) Interaktionspartner

  1. These findings indicate that greater synthesis of phosphatidylcholine (zeige SGMS1 Antikörper) and antioxidants contribute to the better performance and immuno-metabolic status in methionine-supplemented cows.

Cystathionine-beta-Synthase (CBS) Antigen-Profil

Protein Überblick

The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. Multiple alternatively spliced transcript variants have been found for this gene.

Genbezeichner und Symbole assoziert mit CBS

  • cystathionine-beta-synthase (cbs-a) Antikörper
  • cystathionine-beta-synthase (cbs) Antikörper
  • cystathionine beta-synthase (Cbs) Antikörper
  • cystathionine-beta-synthase (CBS) Antikörper
  • cystathionine beta-synthase (CNA06170) Antikörper
  • cystathionine beta-synthase (Tb11.02.5400) Antikörper
  • cystathionine beta-synthase CBS (cbs) Antikörper
  • cystathionine beta-synthase (cbs) Antikörper
  • cystathionine beta-synthase (cysB) Antikörper
  • cystathionine beta synthase (Cbs) Antikörper
  • cystathionine-beta-synthase (cbs-b) Antikörper
  • cystathionine-beta-synthase b (cbsb) Antikörper
  • AI047524 Antikörper
  • AI303044 Antikörper
  • cb442 Antikörper
  • cbs Antikörper
  • DDBDRAFT_0189727 Antikörper
  • DDBDRAFT_0191292 Antikörper
  • DDB_0189727 Antikörper
  • DDB_0191292 Antikörper
  • GB12529 Antikörper
  • HIP4 Antikörper
  • wu:fb37g05 Antikörper
  • wu:fm61c07 Antikörper
  • wu:fq06c06 Antikörper
  • zgc:113704 Antikörper

Bezeichner auf Proteinebene für CBS

cystathionine-beta-synthase , cystathionine beta-synthase , cystathionine beta-synthase CBS , beta-thionase , hemoprotein H-450 , serine sulfhydrase , methylcysteine synthase

GENE ID SPEZIES
380308 Xenopus laevis
493533 Xenopus (Silurana) tropicalis
551341 Apis mellifera
736626 Pan troglodytes
3253577 Cryptococcus neoformans var. neoformans JEC21
3665875 Trypanosoma brucei brucei strain 927/4 GUTat10.1
4551426 Mycobacterium ulcerans Agy99
6228672 Mycobacterium marinum M
7006755 Rhodospirillum centenum SW
7705918 Gemmatimonas aurantiaca T-27
7712188 Rhodococcus erythropolis PR4
7746532 Rhodococcus opacus B4
8616308 Dictyostelium discoideum AX4
100136726 Oncorhynchus mykiss
100635325 Amphimedon queenslandica
24250 Rattus norvegicus
12411 Mus musculus
446655 Xenopus laevis
418545 Gallus gallus
875 Homo sapiens
611071 Canis lupus familiaris
514525 Bos taurus
100008766 Oryctolagus cuniculus
266987 Danio rerio
Ausgewählte Anbieter für anti-Cystathionine-beta-Synthase (CBS) Antikörper
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