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Cyclophilin D (CYPD) ELISA Kits

The protein encoded by CYPD is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family.

list all ELISA KIts Gen GeneID UniProt
Anti-Ratte CYPD CYPD 361967 Q6DGG0
Anti-Human CYPD CYPD 5481 Q08752
Anti-Maus CYPD CYPD 105675 Q99KR7
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Weitere ELISA Kits für Cyclophilin D Interaktionspartner

Human Cyclophilin D (CYPD) Interaktionspartner

  1. The influx of unfolded p53 (zeige TP53 ELISA Kits) into the mitochondrial matrix in response to oxidative stress indirectly activates the normally inhibited CypD by displacing it from Trap1 (zeige TRAP1 ELISA Kits) complexes. This activates CypD's isomerase activity. Liberated CypD then isomerizes multiple proteins including p53 (zeige TP53 ELISA Kits) (causing p53 (zeige TP53 ELISA Kits) aggregation) and the structural components of the mPTP (zeige PTPN2 ELISA Kits) pore, inducing pore opening.

  2. The present study is to investigate the role of CypD in regulating the mitochondrial dynamics relevant to oxidative stress induced (zeige SQSTM1 ELISA Kits) neuron dysfunctions.

  3. CyPD regulates mitochondrial metabolism, and likely cell survival, by promoting more efficient electrons flow through the respiratory chain via increased supercomplex formation

  4. cyclophilin D (zeige PPIF ELISA Kits) may modify mitochondrial features by inducing the translocation of molecules to the mitochondria through the mechanism associated with cellular energy metabolism

  5. The thermodynamics of binding of Cyp-40 (zeige PPID ELISA Kits) to Hsp90 (zeige HSP90 ELISA Kits) shows remarkable temperature sensitivity in the physiological temperature range.

  6. cyclophilin-D (zeige PPIF ELISA Kits) protein could increase oxidative stress and cause endothelial cell injury and apoptosis. cyclophilin-D (zeige PPIF ELISA Kits) protein is the key factor in reactive oxygen species-induced mitochondrial damage, leading to apoptosis of endothelial cells.

  7. Results show that CypD interacts with SPG7 and VDAC to form the mitochondrial permeability transition pore complex (PTP)and its CsA-binding region is necessary for PTP formation.

  8. molecular determinants necessary for Cyclophilin D (zeige PPIF ELISA Kits) activity regulation and binding to proposed pore constituents thereby regulating the mitochondrial permeability transition pore.

  9. Cyp-D (zeige PPIF ELISA Kits) silencing down-regulated mitochondrial transcripts initiated from the heavy strand promoter 2 [i.e., NADH dehydrogenase 1 (ND1 (zeige MT-ND1 ELISA Kits)) by 11-fold; cytochrome oxidase 1 (COX1 (zeige COX1 ELISA Kits)) by 4-fold; and ATP synthase subunit 6 (ATP6 (zeige MT-ATP6 ELISA Kits)) by 6.5-fold.

  10. Cyp40 binds to C2I in vitro and in intact cells, it also interacts with the enzyme components of iota toxin and CDT, suggesting a common principle for this toxin family.

Cow (Bovine) Cyclophilin D (CYPD) Interaktionspartner

  1. Mannheimia haemolytica leukotoxin binds cyclophilin D (zeige PPIF ELISA Kits) on bovine neutrophil mitochondria.

Mouse (Murine) Cyclophilin D (CYPD) Interaktionspartner

  1. Ppif (zeige PPID ELISA Kits)+/+ and Ppif (zeige PPID ELISA Kits)-/- eosinophils exhibited no significant difference in apoptosis or secondary necrosis.

  2. Ischemic postconditioning might prevent lethal reperfusion injury through an increased SIRT3 (zeige SIRT3 ELISA Kits) activity and subsequent attenuation of CyPD acetylation at reperfusion.

  3. These findings reveal the role of HAX-1 (zeige HAX1 ELISA Kits) in regulating cyclophilin-D (zeige PPIF ELISA Kits) levels via an Hsp90 (zeige HSP90 ELISA Kits)-dependent mechanism, resulting in protection against activation of mPTP (zeige PTPN2 ELISA Kits) and subsequent cell death responses

  4. study identifies a novel signaling pathway composed of E2F1 (zeige E2F1 ELISA Kits), miR (zeige MLXIP ELISA Kits)-30b and CypD that regulates myocardial necrosis.

  5. It is concluded that CypD sensitizes the brain mitochondria to PT, and its inhibition by CsA (zeige HSPA9 ELISA Kits) or CypD absence improves the complex I-related mitochondrial function and increases mitochondria stability against Ca(2 (zeige CA2 ELISA Kits)+) stress.

  6. Data indicate that Ppif (zeige PPID ELISA Kits) protein cyclophilin D (CypD)-dependent protein kinase A (PKA)/cAMP regulatory-element-binding (CREB (zeige CREB1 ELISA Kits)) signaling is responsible for amyloid beta (Abeta (zeige APP ELISA Kits))-induced synaptic injury.

  7. Ablation of CypD leads to changes in the mitochondrial acetylome which may contribute to altered mitochondrial metabolism in CypD-deficient mice.

  8. These results suggest a physiologic function for CypD and the mitochondrial permeability transition in the regulation of starvation-induced autophagy.

  9. new insights into CypD-dependent mitochondrial mPTP (zeige PTPN2 ELISA Kits) and signaling on mitochondrial trafficking in axons and synaptic degeneration in an environment enriched for Abeta (zeige APP ELISA Kits)

  10. Cys (zeige DNAJC5 ELISA Kits)-203 residue of CypD is necessary for redox stress-induced activation of mPTP (zeige PTPN2 ELISA Kits).

Cyclophilin D (CYPD) Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein has been shown to possess PPIase activity and, similar to other family members, can bind to the immunosuppressant cyclosporin A.

Genbezeichner und Symbole assoziert mit Cyclophilin D (CYPD) ELISA Kits

  • cyclophilin D (cypD) Antikörper
  • cyclophilin D (LOC100152612) Antikörper
  • peptidylprolyl isomerase D (Ppid) Antikörper
  • peptidylprolyl isomerase D (PPID) Antikörper
  • peptidylprolyl isomerase F (PPIF) Antikörper
  • peptidylprolyl isomerase F (cyclophilin F) (Ppif) Antikörper
  • AW457192 Antikörper
  • CYP-40 Antikörper
  • CyP-D Antikörper
  • CyP-F Antikörper
  • CYPD Antikörper
  • DDBDRAFT_0205184 Antikörper
  • DDBDRAFT_0215377 Antikörper
  • DDB_0205184 Antikörper
  • DDB_0215377 Antikörper
  • PPIase Antikörper

Bezeichner auf Proteinebene für Cyclophilin D (CYPD) ELISA Kits

40 kDa peptidyl-prolyl cis-trans isomerase , Cyclophilin D , PPIase D , cyclophilin-40 , peptidyl-prolyl cis-trans isomerase D , rotamase D , 40 kDa peptidyl-prolyl cis-trans isomerase D , cyclophilin 40 , cyclophilin D , cyclophilin-related protein , PPIase F , cyclophilin F , peptidyl-prolyl cis-trans isomerase F, mitochondrial , peptidyl-prolyl cis-trans isomerase, mitochondrial , peptidylprolyl isomerase F (cyclophilin F) , rotamase F , mitochondrial Cyclophilin D

GENE ID SPEZIES
8622540 Dictyostelium discoideum AX4
100152612 Sus scrofa
361967 Rattus norvegicus
5481 Homo sapiens
414346 Bos taurus
423723 Gallus gallus
105675 Mus musculus
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