anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 2 (p39) (CDK5R2) Antikörper

The protein encoded by CDK5R2 is a neuron-specific activator of CDK5 kinase. Zusätzlich bieten wir Ihnen Cyclin-Dependent Kinase 5, Regulatory Subunit 2 (p39) Kits (1) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CDK5R2 501164  
CDK5R2 8941 Q13319
CDK5R2 12570 O35926
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Top anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 2 (p39) Antikörper auf antikoerper-online.de

Showing 10 out of 28 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from HuvEc cells, using CDK5R2 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-CDK5R2 Antibody Titration: 1.0 ug/ml Positive Control: NCI-H226 Whole Cell 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
385,00 €
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Human Kaninchen Unkonjugiert IHC, WB Western Blot: CDK5R2 Antibody [ABIN4082291] - Analysis of CDK5R2 at 1:500 dilution. Lane 1 - HEK293T whole cell lysate, Lane 2 - Raw264.7 whole cell lysate, Lane 3 - H9C2 whole cell lysate. 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
341,00 €
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Human Kaninchen Unkonjugiert ELISA, WB 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
565,71 €
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Human Kaninchen Unkonjugiert WB   50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
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Human Kaninchen Unkonjugiert IHC, WB   100 μL Anmelden zum Anzeigen 11 bis 14 Tage
618,10 €
Details
Human Kaninchen Unkonjugiert ELISA, IHC   200 μL Anmelden zum Anzeigen 11 bis 14 Tage
941,11 €
Details
Human Kaninchen HRP IHC, ELISA   200 μL Anmelden zum Anzeigen 11 bis 14 Tage
1.203,02 €
Details
Human Kaninchen PE IHC, ELISA   200 μL Anmelden zum Anzeigen 11 bis 14 Tage
1.203,02 €
Details

CDK5R2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Rat (Rattus)


Human , ,
,

, , , , ,
Mouse (Murine)


Am meisten referenzierte anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 2 (p39) Antikörper

  1. Human Polyclonal CDK5R2 Primary Antibody für ELISA, WB - ABIN1533863 : Hillier, Graves, Fulton, Fulton, Pepin, Minx, Wagner-McPherson, Layman, Wylie, Sekhon, Becker, Fewell, Delehaunty, Miner, Nash, Kremitzki, Oddy, Du, Sun, Bradshaw-Cordum, Ali, Carter, Cordes, Harris et al.: Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ... in Nature 2005 (PubMed)

Weitere Antikörper gegen Cyclin-Dependent Kinase 5, Regulatory Subunit 2 (p39) Interaktionspartner

Human Cyclin-Dependent Kinase 5, Regulatory Subunit 2 (p39) (CDK5R2) Interaktionspartner

  1. p39 (zeige JUN Antikörper) is essential for recruiting scaffolding protein muskelin (zeige MKLN1 Antikörper) to stress fibers.

  2. Structural basis for the different stability and activity between the Cdk5 (zeige CDK5 Antikörper) complexes with p35 (zeige ANXA1 Antikörper) and p39 (zeige JUN Antikörper) activators.

  3. Hepatocellular carcinoma patients with lower p39 (zeige JUN Antikörper) expression had poorer overall survival rate than that with high expression.

  4. both proteasomal degradation and calpain cleavage of p35 (zeige ANXA1 Antikörper) and p39 (zeige JUN Antikörper) are stimulated by membrane association, which is in turn mediated via myristoylation of their p10 (zeige S100A10 Antikörper) regions.

  5. Our data suggest that neurotoxic insults lead to calpain-mediated conversion of p39 (zeige JUN Antikörper) to p29 (zeige PRTN3 Antikörper), which might contribute to deregulation of Cdk5 (zeige CDK5 Antikörper)

  6. role of the CDK5 (zeige CDK5 Antikörper) molecular complex in the genetic etiology of early-onset Alzheimer disease; a yet unknown functional variant in CDK5 (zeige CDK5 Antikörper) or in a nearby gene might lead to increased susceptibility for early-onset Alzheimer disease

Mouse (Murine) Cyclin-Dependent Kinase 5, Regulatory Subunit 2 (p39) (CDK5R2) Interaktionspartner

  1. In this study, we discovered that selective upregulation of p39 (zeige ATP6V0D1 Antikörper) is the underlying mechanism that accommodates the increased functional requirement of Cdk5 (zeige CDK5 Antikörper) activation during neuronal differentiation. In addition, we demonstrated that p39 (zeige ATP6V0D1 Antikörper) selectively directs Cdk5 (zeige CDK5 Antikörper) to phosphorylate protein substrates essential for axonal development, dendritic spine formation, and synaptogenesis. Moreover, our studies suggest opposing roles o

  2. These data suggest p35 (zeige CDK5R1 Antikörper) and p39 (zeige ATP6V0D1 Antikörper) have specific and overlapping roles in oligodendrocyte development, some of which may be independent of Cdk5 (zeige CDK5 Antikörper) activation.

  3. it was found that Tyr (zeige TYR Antikörper)-15 phosphorylation occurred only on monomeric Cdk5 (zeige CDK5 Antikörper), and the coexpression of activators, p35/p25 (zeige CDK5R1 Antikörper), p39 (zeige ATP6V0D1 Antikörper), or Cyclin I (zeige CCNI Antikörper), inhibited the phosphorylation.

  4. Structural basis for the different stability and activity between the Cdk5 (zeige CDK5 Antikörper) complexes with p35 (zeige CDK5R1 Antikörper) and p39 (zeige ATP6V0D1 Antikörper) activators.

  5. Data indicate that p39 (zeige ATP6V0D1 Antikörper) is selectively up-regulated in oligodendroglia (OL) during differentiation along with elevated Cdk5 (zeige CDK5 Antikörper) activity.

  6. A set of REST target genes, including Cdk5r2, is important for beta cell survival.

  7. The alternating p39 (zeige ATP6V0D1 Antikörper) parasagittal band pattern may reflect a role for p39 (zeige ATP6V0D1 Antikörper) or Cdk5 (zeige CDK5 Antikörper)/p39 (zeige ATP6V0D1 Antikörper) in the functional compartmentation of the cerebellum.

  8. Data show that both p35 (zeige CDK5R1 Antikörper) and p39 (zeige ATP6V0D1 Antikörper) are expressed in insulin (zeige INS Antikörper)-secreting beta cells, where they exhibit individual subcellular distributions and associate with membranous organelles of different densities.

  9. These findings demonstrate that Cdk5 (zeige CDK5 Antikörper), p35 (zeige CDK5R1 Antikörper), and p39 (zeige ATP6V0D1 Antikörper) are endogenously expressed in NG108-15 cells, exhibit distinct subcellular localizations, and that both Cdk5 (zeige CDK5 Antikörper)/p35 (zeige CDK5R1 Antikörper) and Cdk5 (zeige CDK5 Antikörper)/p39 (zeige ATP6V0D1 Antikörper) are central in formation of functional synapses.

  10. The differential nuclear accumulation of p39 (zeige ATP6V0D1 Antikörper) and p35 (zeige CDK5R1 Antikörper) suggests their segregated functions, p35 (zeige CDK5R1 Antikörper)-Cdk5 (zeige CDK5 Antikörper) in the cytoplasm and p39 (zeige ATP6V0D1 Antikörper)-Cdk5 (zeige CDK5 Antikörper) in the nucleus.

Cyclin-Dependent Kinase 5, Regulatory Subunit 2 (p39) (CDK5R2) Antigen-Profil

Protein Überblick

The protein encoded by this gene is a neuron-specific activator of CDK5 kinase. It associates with CDK5 to form an active kinase. This protein and neuron-specific CDK5 activator CDK5R1/p39NCK5A both share limited similarity to cyclins, and thus may define a distinct family of cyclin-dependent kinase activating proteins.

Genbezeichner und Symbole assoziert mit CDK5R2

  • cyclin-dependent kinase 5, regulatory subunit 2 (p39) (CDK5R2) Antikörper
  • cyclin-dependent kinase 5, regulatory subunit 2 (p39) (Cdk5r2) Antikörper
  • cyclin-dependent kinase 5, regulatory subunit 2a (p39) (cdk5r2a) Antikörper
  • cyclin-dependent kinase 5, regulatory subunit 2 (p39) (cdk5r2) Antikörper
  • B230310J22Rik Antikörper
  • cdk5r2 Antikörper
  • MGC115331 Antikörper
  • NCK5AI Antikörper
  • p39 Antikörper
  • p39nck5ai Antikörper
  • RGD1562530 Antikörper
  • wu:fj48b05 Antikörper
  • zgc:110126 Antikörper

Bezeichner auf Proteinebene für CDK5R2

cyclin-dependent kinase 5, regulatory subunit 2 (p39) , cyclin-dependent kinase 5 activator 2 , cyclin-dependent kinase 5, regulatory subunit 2-like , p39 , fj48b05 , CDK5 activator 2 , cyclin-dependent kinase 5 activator isoform p39i , cyclin-dependent kinase 5 regulatory subunit 2 , neuronal CDK5 activator isoform , p39I

GENE ID SPEZIES
459953 Pan troglodytes
488529 Canis lupus familiaris
501164 Rattus norvegicus
528533 Bos taurus
550231 Danio rerio
734425 Xenopus laevis
8941 Homo sapiens
12570 Mus musculus
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