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CORT encodes a neuropeptide that is structurally similar to somatostatin. Zusätzlich bieten wir Ihnen CST Antikörper (36) und CST Kits (27) und viele weitere Produktgruppen zu diesem Protein an.
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GHRL (zeige GHRL Proteine), LEP (zeige LEP Proteine), ADIP (zeige SSX2IP Proteine), INS (zeige INS Proteine) and CORT concentrations were measured using radioimmunoassay
Cortistatin emerges as a natural endogenous regulator of smooth muscle cells under pathological conditions and an attractive candidate for the pharmacological management of vascular diseases that course with neointimal lesion formation.
The cortistatin expression in the temporal lobe of Alzheimer's disease patients is decressed.
Endocrine activities of cortistatin-14 and its interaction with GHRH (zeige GHRH Proteine) and ghrelin (zeige GHRL Proteine) in humans.
first extensive study demonstrating that lymphoid tissues and immune cells express different levels of CST (zeige GAL3ST1 Proteine) mRNA and that its expression can be regulated; hypothesize a role as an endogenous ligand of at least the sst2 (zeige SSTR2 Proteine) receptor in the immune system
study demonstrates for the first time a selective and inducible expression of the recently discovered cortistatin, as well as somatostatin receptor 2 (zeige SSTR2 Proteine), in human monocyte-derived cells
cortistatin-14 shown to be a high affinity ligand for G protein coupled receptor MrgX2 (zeige MRGPRX2 Proteine) which is expressed in dorsal root ganglion
Cortistatin plays a role in the auto/paracrine regulation of the endocrine pancreas
Intravitreous somatostatin (zeige SST Proteine)-like immunoreactivity deficit occurs in ptients with proliferative diabetic retinopathy.
Human immune cells produce CST (zeige GAL3ST1 Proteine), whereas macrophage lineage and activated endothelium express sst2 (zeige SSTR2 Proteine), and human lymphocytes express sst3. The human thymus expresses sst1 (zeige SSTR1 Proteine), 2, 3, MrgX2 (zeige MRGPRX2 Proteine) and almost all immune cells express GHS-R (zeige GHSR Proteine). [review]
A lower expression of CST (zeige GAL3ST1 Proteine) exists in diabetic retinas and it is associated with retinal neurodegeneration.
Endogenous SST (zeige SST Proteine) and CORT distinctly impact on DMBA-induced mammary gland tumorigenesis , in a manner that is strongly dependent on the metabolic/endocrine milieu (lean vs. obese status).
This study demonistrated that Cortistatin attenuates inflammatory pain via spinal and peripheral actions.
endogenous CORT is essential for the obesity-induced changes in insulin (zeige INS Proteine) expression/secretion observed in mice
the role of endogenous CST is different from SST (zeige SST Proteine); CST exerted an unexpected stimulatory role on prolactin (zeige PRL Proteine) secretion
Regulation of cortistatin-expressing interneurons by activity-dependent BDNF (zeige BDNF Proteine) expression may contribute to regulation of sleep behavior.
Cortistatin mRNA concentration in the hippocampus and dentate gyrus is significantly increased in aged non-transgenic (Tg) mice compared with young non-Tg mice.
This gene encodes a neuropeptide that is structurally similar to somatostatin. It binds to all known somatostatin receptors, and shares many pharmacological and functional properties with somatostatin, including the depression of neuronal activity. However, it also has many properties distinct from somatostatin, such as induction of slow-wave sleep, apparently by antagonism of the excitatory effects of acetylcholine on the cortex, reduction of locomotor activity, and activation of cation selective currents not responsive to somatostatin. The preproprotein undergoes further processing into multiple mature products. Read-through transcripts exist between this gene and the upstream APITD1 (apoptosis-inducing, TAF9-like domain 1) gene, as represented in GeneID:100526739.
, cortistatin preproprotein-like