anti-Contactin Associated Protein-Like 2 (CNTNAP2) Antikörper

CNTNAP2 encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. Zusätzlich bieten wir Ihnen CNTNAP2 Kits (7) und CNTNAP2 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CNTNAP2 26047 Q9UHC6
CNTNAP2 66797 Q9CPW0
CNTNAP2 500105  
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Top anti-CNTNAP2 Antikörper auf antikoerper-online.de

Showing 10 out of 76 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of CNTNAP2 Antibody (Center) in CEM cell line lysates (35ug/lane). CNTNAP2 (arrow) was detected using the purified Pab. 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Maus Unkonjugiert IHC, IHC (fro), IHC (p), IP, WB Western Blot: Caspr2 Antibody (S67-25) [NBP1-49575] - Lane 1: HEK293T control cell lysate and Lane2: Caspr2 plasmid transfected HEK293T cell lysate. Image from verified customer review. Immunohistochemistry-Frozen: Caspr2 Antibody (S67-25) [NBP1-49575] - in frozen sections of mouse brain extract using this antibody. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$500.06
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: Caspr2 Antibody [NBP1-88182] - Staining of human cell line A-431 shows positivity in centrosome. Western Blot: Caspr2 Antibody [NBP1-88182] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Negative control (vector only transfected HEK293T lysate).Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY402278) 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$439.69
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (fro), WB Western Blot: Caspr2 Antibody [NBP1-31358] - Sample (30 ug of whole cell lysate)A: MOLT4 5% SDS PAGE, antibody diluted at 1:5000. Western Blot: Caspr2 Antibody [NBP1-31358] - Sample (50 ug of whole cell lysate) A: Mouse brain 5% SDS PAGE; antibody diluted at 1:10000. 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$447.56
Details
Human Kaninchen Unkonjugiert   100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$257.40
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse brain labeled with Anti Caspr2 Polyclonal Antibody, Unconjugated (ABIN1386423) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$295.90
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of CNTNAP2 Antibody (Center) (ABIN652646) in CEM cell line lysates (35 µg/lane). CNTNAP2 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded mouse brain tissue reacted with CNTNAP2 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Maus Kaninchen Unkonjugiert ELISA   100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$163.90
Details
Human Kaninchen Alexa Fluor 594 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details
Human Kaninchen Cy3 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details

CNTNAP2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-CNTNAP2 Antikörper

  1. Mammalian Monoclonal CNTNAP2 Primary Antibody für ISt, IHC - ABIN1304572 : Varea, Martin-de-Saavedra, Kopeikina, Schürmann, Fleming, Fawcett-Patel, Bach, Jang, Peles, Kim, Penzes: Synaptic abnormalities and cytoplasmic glutamate receptor aggregates in contactin associated protein-like 2/Caspr2 knockout neurons. in Proceedings of the National Academy of Sciences of the United States of America 2015 (PubMed)
    Show all 6 Pubmed References

  2. Human Monoclonal CNTNAP2 Primary Antibody für IHC, IHC (fro) - ABIN4288205 : Horresh, Bar, Kissil, Peles: Organization of myelinated axons by Caspr and Caspr2 requires the cytoskeletal adapter protein 4.1B. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 (PubMed)

  3. Human Polyclonal CNTNAP2 Primary Antibody für - ABIN2017587 : Chen, Koopmans, Gordon, Paliukhovich, Klaassen, van der Schors, Peles, Verhage, Smit, Li: Interaction proteomics of canonical Caspr2 (CNTNAP2) reveals the presence of two Caspr2 isoforms with overlapping interactomes. in Biochimica et biophysica acta 2015 (PubMed)

  4. Human Polyclonal CNTNAP2 Primary Antibody für IHC, IHC (p) - ABIN4288206 : Krumbiegel, Pasutto, Schlötzer-Schrehardt, Uebe, Zenkel, Mardin, Weisschuh, Paoli, Gramer, Becker, Ekici, Weber, Nürnberg, Kruse, Reis: Genome-wide association study with DNA pooling identifies variants at CNTNAP2 associated with pseudoexfoliation syndrome. in European journal of human genetics : EJHG 2011 (PubMed)

Weitere Antikörper gegen CNTNAP2 Interaktionspartner

Human Contactin Associated Protein-Like 2 (CNTNAP2) Interaktionspartner

  1. Subjects with greater left dorsolateral prefrontal cortex (DLPFC) surface area had better cognitive performance. Importantly, the left DLPFC surface area mediated the association between the CNTNAP2 rs4726946 genotype and cognitive performance. This study provides the first evidence for associations among the CNTNAP2 gene, left DLPFC structure, and cognitive control.

  2. associations of a common CNTNAP2 polymorphism (rs7794745) with variation in grey matter in a region in the dorsal visual stream

  3. Bi-allelic aberrations (mutations and copy number variants) in CNTNAP2 in eight individuals with intellectual disability and epilepsy were reported.

  4. Older age is a strong predictor of CNS involvement in patients seropositive for CASPR2-IgG or LGI1 (zeige LGI1 Antikörper)-IgG. Pain, peripheral manifestations, and stereotypic paroxysmal dizziness spells are common with LGI1 (zeige LGI1 Antikörper)-IgG.

  5. Caspr2 antibodies associate with a treatable disorder that predominantly affects elderly men. The resulting syndrome may vary among patients but it usually includes a set of well-established symptoms.

  6. The molecular shape and dimensions of CNTNAP2 place constraints on how CNTNAP2 integrates in the cleft of axo (zeige MARCH7 Antikörper)-glial and neuronal contact sites and how it functions as an organizing and adhesive molecule.

  7. A significant association was found between rs7794745 CNTNAP2 gene polymorphism and autism in an Iranian population.

  8. rs7794745 in the CNTNAP2 gene was associated with autistic spectrum disorder in Brazilian patients.

  9. we could not detect any significant association with the CNTNAP2 gene and high functioning autism

  10. CNTNAP2 is transcriptionally regulated by FOXP2 (zeige FOXP2 Antikörper).

Mouse (Murine) Contactin Associated Protein-Like 2 (CNTNAP2) Interaktionspartner

  1. Cntnap2 KO rats exhibited severe motor seizures, hyperactivity, and increased consolidation of wakefulness and REM (zeige REM1 Antikörper) sleep. By contrast, Cntnap2 KO mice demonstrated absence seizure-like events, hypoactivity, and wake fragmentation.

  2. After middle cerebral artery occlusion mice demonstrate profoundly impaired socially evoked USVs. In addition, there is suppression of the language-associated transcription factor,contactin-associated protein 2 (Cntnap2).

  3. Olfaction-based behavioral tests revealed that mice lacking Caspr2 exhibit abnormal response to sensory stimuli and lack preference for novel odors.

  4. Mice with the Cntnap2 genetic mutation showed a dissociation of auditory-processing abilities

  5. Study reports behavioral characterization of mouse models of autism with null mutation in Cntnap2 gene. It shows hyperactivity, mild gait phenotype and reduced vocalizations among others.

  6. new dendritic spines in mice lacking CNTNAP2 were formed at normal rates, but failed to stabilize. Notably, rates of spine elimination were unaltered, suggesting a specific role for CNTNAP2 in stabilizing new synaptic circuitry

  7. Cntnap2 deletion selectively impairs perisomatic hippocampal inhibition while sparing excitation provide additional support for synaptic dysfunction as a common mechanism underlying autism spectrum disorders

  8. The CASPR2/MUPP1 (zeige MPDZ Antikörper) receptor complex co-localized with GPR37 (zeige GPR37 Antikörper) in hippocampal neurons.

  9. Interaction proteomics revealed the interactors of Caspr2, including CNTN2 (zeige CNTN2 Antikörper), KCNAs, members of the ADAM family (ADAM22 (zeige ADAM22 Antikörper), ADAM23 (zeige Adam23 Antikörper) and ADAM11 (zeige ADAM11 Antikörper)), members of LGI family and MAGUKs (DLGs and MPPs (zeige MPHOSPH6 Antikörper)).

  10. CNTNAP2 has a role in the correct trafficking of GluA1 (zeige GRIA1 Antikörper) AMPA (zeige GRIA3 Antikörper)-type glutamate (zeige GRIN1 Antikörper) receptors

CNTNAP2 Antigen-Profil

Protein Überblick

This gene encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons. This gene encompasses almost 1.5% of chromosome 7 and is one of the largest genes in the human genome. It is directly bound and regulated by forkhead box protein P2 (FOXP2), a transcription factor related to speech and language development. This gene has been implicated in multiple neurodevelopmental disorders, including Gilles de la Tourette syndrome, schizophrenia, epilepsy, autism, ADHD and mental retardation.

Genbezeichner und Symbole assoziert mit CNTNAP2

  • contactin associated protein like 2 (CNTNAP2) Antikörper
  • contactin associated protein-like 2 (Cntnap2) Antikörper
  • contactin associated protein-like 2 (CNTNAP2) Antikörper
  • contactin associated protein like 2b (cntnap2b) Antikörper
  • contactin associated protein like 2 (cntnap2) Antikörper
  • contactin associated protein like 2 (Cntnap2) Antikörper
  • 5430425M22Rik Antikörper
  • AUTS15 Antikörper
  • CASPR Antikörper
  • Caspr2 Antikörper
  • CDFE Antikörper
  • MGC145769 Antikörper
  • MGC147944 Antikörper
  • MGC147981 Antikörper
  • mKIAA0868 Antikörper
  • NRXN4 Antikörper
  • PTHSL1 Antikörper

Bezeichner auf Proteinebene für CNTNAP2

cell recognition molecule Caspr2 , contactin-associated protein-like 2 , homolog of Drosophila neurexin IV , contactin associated protein-like 2 , novel protein similar to H.sapiens contactin associated protein , contactin associated protein 2 , contactin-associated protein-like 2-like

GENE ID SPEZIES
26047 Homo sapiens
66797 Mus musculus
463819 Pan troglodytes
516395 Bos taurus
563345 Danio rerio
574172 Macaca mulatta
780189 Xenopus (Silurana) tropicalis
100174321 Pongo abelii
100013863 Monodelphis domestica
100060296 Equus caballus
100073864 Ornithorhynchus anatinus
100223892 Taeniopygia guttata
100354524 Oryctolagus cuniculus
100397041 Callithrix jacchus
100607262 Nomascus leucogenys
500105 Rattus norvegicus
100717858 Cavia porcellus
100687859 Canis lupus familiaris
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