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The protein encoded by CNTN6 is a member of the immunoglobulin superfamily. Zusätzlich bieten wir Ihnen Contactin 6 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.
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Clinical investigations of the patients carrying CNTN5 (zeige CNTN5 Antikörper) or CNTN6 variants showed that they were hypersensitive to sounds (a condition called hyperacusis) and displayed changes in wave latency within the auditory pathway.
CNTN6 copy number variants (duplications) were associated with increased risk of Tourette syndrome.
results do not support the candidacy of CHL1 (zeige DDX11 Antikörper), CNTN6, and CNTN4 (zeige CNTN4 Antikörper) as tumor suppressor genes in the 3p26-pter (zeige PTER Antikörper) region in ovarian cancer
Cntn6 engages in both trans- and cis (zeige CISH Antikörper)-interactions and may be involved in larger protein interaction networks.
These findings demonstrate that NB-3 trans-homophilic interactions mediate the cross-talk between post-traumatic axons and scar-forming cells and impair the intrinsic growth ability of injured axons.
Protein-tyrosine phosphatase receptor type G (RPTPgamma/PTPRG (zeige PTPRG Antikörper)) interacts in vitro with contactin-3 (zeige CNTN3 Antikörper)-6 (CNTN3 (zeige CNTN3 Antikörper)-6), a group of glycophosphatidylinositol-anchored cell adhesion molecules involved in the wiring of the nervous system
our data suggest that adropin (zeige ENHO Antikörper) is a membrane-bound protein that interacts with the brain-specific (zeige CALY Antikörper) Notch1 (zeige NOTCH1 Antikörper) ligand NB3
NB-3 is involved in the normal projection and terminal branching of developing corticospinal tract axons.
the PTPalpha (zeige PTPRA Antikörper)-mediated increase of NB-3 level at the cell surface represents a novel function of PTPalpha (zeige PTPRA Antikörper) in NB-3 signaling in neural development
NB-3 has key roles in the formation of glutamatergic, but not GABAergic, synapses during postnatal development of the hippocampal formation as well as the cerebellum.
Mice deficient for NB-3 are slow to learn to stay on the rotating rod in the rotorod test during repeated trials and display dysfunction of equilibrium and vestibular senses in the wire hang and horizontal rod-walking tests.
NB-3/Notch1 (zeige NOTCH1 Antikörper) pathway promotes neural progenitor cell differentiation into oligodendrocytes via Deltex1.
Both CHL1 (zeige CHL1 Antikörper) and NB-3 interact with protein tyrosine phosphatase alpha (PTPalpha (zeige PTPRA Antikörper)) and regulate its activity in the developing caudal (zeige CAD Antikörper) cortex.
The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system.
, neural adhesion molecule
, neural recognition molecule NB-3