anti-Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) Antikörper

The protein encoded by CSF3R is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. Zusätzlich bieten wir Ihnen CSF3R Kits (42) und CSF3R Proteine (26) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CSF3R 1441 Q99062
CSF3R 12986 P40223
CSF3R 298518  
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Top anti-CSF3R Antikörper auf antikoerper-online.de

Showing 10 out of 212 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, FACS, IHC (p), WB Flow Cytometry analysis of ZR-75-1 cells using CD114 / CSF3R Antibody (Center) Cat.-No AP51098PU-N (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Formalin-fixed, paraffin-embedded human colon carcinoma reacted with CD114 / CSF3R Antibody (Center) Cat.-No AP51098PU-N which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Maus Fluorescein FACS 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$270.25
Details
Human Maus PE FACS Detection of G-CSF R/CD114 in Human Granulocytes by Flow Cytometry. Human granulocytes were stained with Mouse Anti-Human G-CSF R/CD114 PE-conjugated Monoclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$328.90
Details
Human Maus Unkonjugiert CyTOF, ELISA (Capture), FACS, WB Detection of Human G-CSF R/CD114 by Western Blot. Western blot shows lysates of AML-193 human acute monocytic leukemia cell line. PVDF membrane was probed with 0.5 ug/mL of Mouse Anti-Human G-CSF R/CD114 Monoclonal Antibody. This experiment was conducted under reducing conditions. 500 μg Anmelden zum Anzeigen 8 bis 9 Tage
$387.55
Details
Human Maus Unkonjugiert CyTOF, FACS, WB Detection of Human G-CSF R/CD114 by Western Blot. Western blot shows lysates of AML-193 human acute monocytic leukemia cell line. PVDF membrane was probed with 1 ug/mL of Mouse Anti-Human G-CSF R/CD114 Monoclonal Antibody. This experiment was conducted under reducing conditions. 500 μg Anmelden zum Anzeigen 8 bis 9 Tage
$387.55
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti-G-CSFR/CD114 Polyclonal Antibody, Unconjugated (ABIN742275) at 1:600 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$318.45
Details
Human Maus PE FACS   25 Tests Anmelden zum Anzeigen 6 bis 8 Tage
$253.00
Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details
Human Kaninchen Unkonjugiert WB Anti-GCSF Receptor antibody, Western blotting WB: Human Placenta Tissue Lysate 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$200.00
Details
Human Ziege Unkonjugiert ELISA   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$242.88
Details

CSF3R Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-CSF3R Antikörper

  1. Human Monoclonal CSF3R Primary Antibody für FACS - ABIN2478112 : Curtis, Patel: Pharmacy-based analytical toxicology service. in American journal of hospital pharmacy 1975 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal CSF3R Primary Antibody für CyTOF, FACS - ABIN4899922 : Shao, Xu, Jing, Tweardy: Unique structural determinants for Stat3 recruitment and activation by the granulocyte colony-stimulating factor receptor at phosphotyrosine ligands 704 and 744. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal CSF3R Primary Antibody für IF (p), IHC (p) - ABIN742275 : Tajima, Waki, Tsuchiya, Hoshi et al.: Granulocyte colony-stimulating factor-producing undifferentiated carcinoma of the colon mimicking a pulmonary giant cell carcinoma: a case showing overexpression of CD44 along with highly ... in International journal of clinical and experimental pathology 2014 (PubMed)

  4. Human Polyclonal CSF3R Primary Antibody für ELISA, WB - ABIN4313030 : Meenhuis, Verwijmeren, Roovers, Touw: The deubiquitinating enzyme DUB2A enhances CSF3 signalling by attenuating lysosomal routing of the CSF3 receptor. in The Biochemical journal 2011 (PubMed)

  5. Human Monoclonal CSF3R Primary Antibody für FACS - ABIN4896903 : Dror, Durie, Ginzberg, Herman, Banerjee, Champagne, Shannon, Malkin, Freedman: Clonal evolution in marrows of patients with Shwachman-Diamond syndrome: a prospective 5-year follow-up study. in Experimental hematology 2002 (PubMed)

  6. Human Monoclonal CSF3R Primary Antibody für FACS - ABIN4896902 : Radomska, Alberich-Jordà, Will, Gonzalez, Delwel, Tenen: Targeting CDK1 promotes FLT3-activated acute myeloid leukemia differentiation through C/EBPα. in The Journal of clinical investigation 2012 (PubMed)

  7. Human Monoclonal CSF3R Primary Antibody für CyTOF, ELISA (Capture) - ABIN4899923 : deBruin, Lincoln, Hartley, Shehabeldin, Van, Szilvassy: Most purported antibodies to the human granulocyte colony-stimulating factor receptor are not specific. in Experimental hematology 2010 (PubMed)

Weitere Antikörper gegen CSF3R Interaktionspartner

Human Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) Interaktionspartner

  1. we have expanded the region of the CSF3R cytoplasmic domain in which truncation or missense mutations exhibit leukemogenic capacity, which will be useful for evaluating the relevance of CSF3R mutations in patients and helpful in defining targeted therapy strategies.

  2. our data demonstrates that E6AP (zeige ube3a Antikörper) facilitates ubiquitination and subsequent degradation of G-CSFR leading to attenuation of its downstream signaling and inhibition of granulocytic differentiation.

  3. study aimed to identity and characterize novel CSF3R extracellular missense mutations from exome sequencing of leukemia patients; results show the structural and functional importance of conserved extracellular cysteine pairs in CSF3R

  4. a central role of enhanced Mapk (zeige MAPK1 Antikörper) signaling in CSF3R-induced leukemia.

  5. CSF3R T618I mutation is associated with Chronic neutrophilic leukemia.

  6. biallelic CSF3R mutations were identified In the group of congenital neutropenia patients; CSF3R mutant clones are highly dynamic and may disappear and reappear during continuous granulocyte colony-stimulating factor (G-CSF (zeige CSF3 Antikörper)) therapy. The time between the first detection of CSF3R mutations and overt leukemia is highly variable

  7. Co-occurrence of mutations in CSF3R and CEBPA (zeige CEBPA Antikörper) in a well-defined AML (zeige RUNX1 Antikörper) subset, which uniformly responds to JAK (zeige JAK3 Antikörper) inhibitors; this paves the way to personalized clinical trials for this disease.

  8. The quantitative methods used in this study have shown non-altered expression levels of different microglial markers (Iba-1 (zeige AIF1 Antikörper), Cd11b (zeige ITGAM Antikörper) and CD68 (zeige CD68 Antikörper)), together with increased expression of IL6 (zeige IL6 Antikörper), IL10RA (zeige IL10RA Antikörper), colony stimulating factor (zeige CSF2 Antikörper) 3 receptor and toll-like receptor 7 (zeige TLR7 Antikörper) in the thalamus in FFI, which explains the seemingly contradictory results of the previous studies.

  9. This study proposes that acquisition of CSF3R mutations may represent a mechanism by which myeloid precursor cells carrying the ELANE (zeige ELANE Antikörper) mutations evade the proapoptotic activity of the Neutrophil Elastase (zeige ELANE Antikörper) mutants in SCN (zeige SRI Antikörper) patients.

  10. CSF3R expression is significantly upregulated in human masticatory mucosa during wound healing

Mouse (Murine) Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) Interaktionspartner

  1. Anti-G-CSF receptor rapidly halted the progression of established disease in collagen Ab-induced arthritis in mice. Neutrophil accumulation in joints was inhibited, without rendering animals neutropenic, suggesting an effect of G-CSF receptor blockade on neutrophil homing to inflammatory sites.

  2. this study shows that dorsal root ganglion neurons cultured in G-CSF (zeige CSF3 Antikörper) failed to respond to G-CSF (zeige CSF3 Antikörper) in vitro, and Csf3r gene expression could not be detected in dorsal root ganglion neurons by single-cell RT-PCR

  3. Thr (zeige TRH Antikörper)-615 and Thr (zeige TRH Antikörper)-618 sites of membrane-proximal mutations are part of an O-linked glycosylation cluster. Mutation at these sites prevents O-glycosylation of CSF3R and increases receptor dimerization.

  4. Fbw7 (zeige FBXW7 Antikörper) together with GSK3beta (zeige GSK3b Antikörper) negatively regulates G-CSFR expression and its downstream signaling.

  5. G-CSFR signaling interacts with retinoic acid receptors in the regulation of myeloid differentiation

  6. Expression of truncated G-CSFR significantly shortens the latency of AML (zeige RUNX1 Antikörper) in a G-CSF (zeige CSF3 Antikörper)-dependent fashion and it is associated with a distinct AML (zeige RUNX1 Antikörper) presentation characterized by higher blast counts and more severe myelosuppression.

  7. G-CSFR signals in bone marrow monocytic cells inhibit the production of trophic factors required for osteoblast lineage cell maintenance, ultimately leading to hematopoietic stem and progenitor cell mobilization.

  8. Signaling mechanisms coupled to tyrosines in the granulocyte colony-stimulating factor receptor orchestrate G-CSF (zeige CSF3 Antikörper)-induced expansion of myeloid progenitor cells.

  9. murine granulocyte colony-stimulating factor receptor binds to a low molecular weight ligand

  10. Mice with truncated G-CSF (zeige CSF3 Antikörper) receptors have neutropenia, susceptibility to infection, and bone marrow maturation arrest similar to severe congenital neutropenic humans, suggesting a role of receptor truncation mutations in SCN (zeige SRI Antikörper) pathology.

Zebrafish Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) Interaktionspartner

  1. GCSF (zeige CSF3 Antikörper)/GCSFR is a conserved signaling system for facilitating the production of multiple myeloid cell lineages, as well as for early myeloid cell migration.

CSF3R Antigen-Profil

Protein Überblick

The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia.

Genbezeichner und Symbole assoziert mit CSF3R

  • colony stimulating factor 3 receptor (CSF3R) Antikörper
  • colony stimulating factor 3 receptor (granulocyte) (Csf3r) Antikörper
  • colony stimulating factor 3 receptor (Csf3r) Antikörper
  • colony stimulating factor 3 receptor (granulocyte) (csf3r) Antikörper
  • colony stimulating factor 3 receptor L homeolog (csf3r.L) Antikörper
  • granulocyte colony-stimulating factor receptor (LOC100433338) Antikörper
  • cd114 Antikörper
  • CSF3R Antikörper
  • Csfgr Antikörper
  • G-CSF-R Antikörper
  • G-CSFR Antikörper
  • gcsfr Antikörper

Bezeichner auf Proteinebene für CSF3R

CD114 antigen , G-CSF receptor , G-CSF-R , granulocyte colony-stimulating factor receptor , colony stimulating factor 3 receptor (granulocyte) , granulocyte stimulating factor receptor , granulocyte colony-stimulating factor receptor-like

GENE ID SPEZIES
1441 Homo sapiens
12986 Mus musculus
100069253 Equus caballus
298518 Rattus norvegicus
100134935 Danio rerio
446770 Xenopus laevis
419620 Gallus gallus
607605 Canis lupus familiaris
456756 Pan troglodytes
713485 Macaca mulatta
100433338 Pongo abelii
100464681 Ailuropoda melanoleuca
101118070 Ovis aries
100717194 Cavia porcellus
511511 Bos taurus
Ausgewählte Anbieter für anti-CSF3R (CSF3R) Antikörper
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