Collectin Sub-Family Member 11 Proteine (COLEC11)

COLEC11 encodes a member of the collectin family of C-type lectins that possess collagen-like sequences and carbohydrate recognition domains. Zusätzlich bieten wir Ihnen COLEC11 Antikörper (42) und COLEC11 Kits (16) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
COLEC11 78989 Q9BWP8
COLEC11 71693 Q3SXB8
Ratte COLEC11 COLEC11 366588  
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Showing 10 out of 11 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
HOST_Mammalian Cells Human His tag   50 μg Anmelden zum Anzeigen 8 bis 9 Tage
341,00 €
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HOST_Baculovirus infected Insect Cells Maus His tag 100 μg Anmelden zum Anzeigen 18 bis 20 Tage
450,00 €
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
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HOST_Human Human His tag   10 μg Anmelden zum Anzeigen 13 bis 15 Tage
190,48 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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Hefe Xenopus laevis His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.503,81 €
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Hefe Huhn His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.503,81 €
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Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.503,81 €
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COLEC11 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , ,
, ,
Mouse (Murine) ,

Weitere Proteine zu Collectin Sub-Family Member 11 (COLEC11) Interaktionspartnern

Human Collectin Sub-Family Member 11 (COLEC11) Interaktionspartner

  1. The exclusion of the MASP1 (zeige MASP1 Proteine) and COLEC11 Loci in two individuals from different consanguineous families and the absence of mutations in four further individuals sequenced for both genes raises the possibility that that there is further genetic heterogeneity of 3MC syndrome

  2. identify collectin (zeige MBL2 Proteine) CL-LK as a novel soluble C-type lectin (zeige MBL2 Proteine) able to bind M. tuberculosis, and characterize mycobacterial mannose-capped lipoarabinomannan as a primary ligand for CL-LK

  3. Data indicate differences in the plasma concentrations of collectin liver 1 (zeige COLEC10 Proteine) and collectin (zeige MBL2 Proteine) kidney 1 (zeige ZNF354A Proteine), M-ficolin (zeige FCN1 Proteine) and H-ficol in systemic lupus erythematosus (SLE) patients compared to a group of healthy controls.

  4. promoter polymorphism COLEC11-9570C>T (rs3820897) was associated with decreased levels of CL-K1.

  5. the sugar specificity of CL-K1 was established.

  6. These results suggest that specific diseases may affect CL-K1 synthesis in an organ dependent manner and that elevated plasma CL-K1 levels are associated with the presence of DIC.

  7. Most plasma CL-K1 was found in complex with CL-L1 (zeige COLEC10 Proteine) in a ratio suggesting a heteromeric subunit of 1 CL-L1 (zeige COLEC10 Proteine) & 2 CL-K1 polypeptides. It associated with MASPs 1, 2 & 3. On binding mannan or DNA in the presence of MASP-2 (zeige MASP2 Proteine), the complex deposited C4b (zeige C4B Proteine).

  8. Data suggest that collectin 11 (CL-11), e.g. via complement, may play a role in response to particles and surfaces presenting extracellular DNA, such as apopototic cells.

  9. collectin-11 associates with all the known MBL (zeige MBL2 Proteine)-associated serine proteases (MASP-1 (zeige MASP1 Proteine), MASP-2 (zeige MASP2 Proteine) and MASP-3 (zeige MASP1 Proteine)) as well as the lectin complement pathway regulator MAP-1 (zeige MASP1 Proteine).

  10. Data show that the concentration of collectin (zeige MBL2 Proteine) kidney 1 (zeige ZNF354A Proteine) (CL-K1, COLEC11) in plasma was 0.34 +/- 0.13 microg/ml and that in mannan-binding lectin (MBL (zeige MBL2 Proteine)) was 1.72 +/- 1.51 microg/ml.

Mouse (Murine) Collectin Sub-Family Member 11 (COLEC11) Interaktionspartner

  1. intrarenal expression of COLEC11 rapidly increases in the postischemic period and colocalizes with complement deposited along the basolateral surface of the proximal renal tubule in association with L-fucose, the potential binding ligand for COLEC11.

  2. identify collectin (zeige MBL2 Proteine) CL-LK as a novel soluble C-type lectin able to bind M. tuberculosis, and characterize mycobacterial mannose-capped lipoarabinomannan as a primary ligand for CL-LK

  3. This profile of CL-K1 expression is unique among the collectins. [CL-K1]

COLEC11 Protein Überblick

Protein Überblick

This gene encodes a member of the collectin family of C-type lectins that possess collagen-like sequences and carbohydrate recognition domains. Collectins are secreted proteins that play important roles in the innate immune system by binding to carbohydrate antigens on microorganisms, facilitating their recognition and removal. The encoded protein binds to multiple sugars with a preference for fucose and mannose. Mutations in this gene are a cause of 3MC syndrome-2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Genbezeichner und Symbole assoziert mit COLEC11

  • collectin sub-family member 11 (COLEC11)
  • collectin sub-family member 11 (LOC100223991)
  • collectin sub-family member 11 (Colec11)
  • collectin sub-family member 11 (colec11)
  • collectin sub-family member 11-like (LOC100345974)
  • 3MC2 Protein
  • 1010001H16Rik Protein
  • CL-K1-I Protein
  • CL-K1-II Protein
  • CL-K1-IIa Protein
  • CL-K1-IIb Protein
  • CLK1 Protein
  • COLEC11 Protein
  • wu:fb82e09 Protein
  • zgc:103572 Protein

Bezeichner auf Proteinebene für COLEC11

collectin sub-family member 11 , collectin kidney protein 1 , collectin-11 , CL-K1 , CL-2 , cCL-2 , collectin 2 , collectin-2

GENE ID SPEZIES
482958 Canis lupus familiaris
707223 Macaca mulatta
743061 Pan troglodytes
100223991 Taeniopygia guttata
78989 Homo sapiens
71693 Mus musculus
613991 Bos taurus
428649 Gallus gallus
366588 Rattus norvegicus
100730989 Cavia porcellus
492459 Danio rerio
380029 Xenopus laevis
100345974 Oryctolagus cuniculus
Ausgewählte Anbieter für COLEC11 Proteine (COLEC11)
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